Donation-induced iron depletion is significantly associated with low hemoglobin at subsequent donations.

Autor: Prinsze FJ; Department of Donor Medicine Research, Donor Studies, Sanquin Research, Amsterdam, the Netherlands., de Groot R; Department of Donor Medicine Research, Donor Studies, Sanquin Research, Amsterdam, the Netherlands., Timmer TC; Department of Donor Medicine Research, Donor Studies, Sanquin Research, Amsterdam, the Netherlands., Zalpuri S; Department of Donor Medicine Research, Donor Studies, Sanquin Research, Amsterdam, the Netherlands.; UCB Pharma, Real World Evidence, Breda, the Netherlands., van den Hurk K; Department of Donor Medicine Research, Donor Studies, Sanquin Research, Amsterdam, the Netherlands.

Publikováno v: Transfusion [Transfusion] 2021 Dec; Vol. 61 (12), pp. 3344-3352. Date of Electronic Publication: 2021 Oct 01.

Development and validation of a universal blood donor genotyping platform: a multinational prospective study.

Autor: Gleadall NS; Department of Haematology, University of Cambridge, Cambridge Biomedical Campus, Cambridge, United Kingdom.; NHS Blood and Transplant, Cambridge Biomedical Campus, Cambridge, United Kingdom., Veldhuisen B; Department of Experimental Immunohematology, Sanquin Research and Landsteiner Laboratory, Amsterdam University Medical Center (AUMC), Amsterdam, The Netherlands.; Department of Diagnostic Immunohematology, Sanquin Diagnostic Services, Amsterdam, The Netherlands., Gollub J; Thermo Fisher Scientific, Santa Clara, CA., Butterworth AS; British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom.; National Institute for Health Research Blood and Transplant Research Unit in Donor Health and Genomics, University of Cambridge, Cambridge, United Kingdom.; Health Data Research UK Cambridge, Wellcome Genome Campus and University of Cambridge, Cambridge, United Kingdom., Ord J; Department of Haematology, University of Cambridge, Cambridge Biomedical Campus, Cambridge, United Kingdom.; NHS Blood and Transplant, Cambridge Biomedical Campus, Cambridge, United Kingdom., Penkett CJ; Department of Haematology, University of Cambridge, Cambridge Biomedical Campus, Cambridge, United Kingdom.; NIHR BioResource, Cambridge University Hospitals, Cambridge Biomedical Campus, Cambridge, United Kingdom., Timmer TC; Department of Donor Medicine Research-Donor Studies, Sanquin Research, Amsterdam, The Netherlands.; Department of Public Health and Landsteiner Laboratory, AUMC, University of Amsterdam, Amsterdam, The Netherlands., Sauer CM; Cancer Research UK Cambridge Institute, University of Cambridge, Cambridge Biomedical Campus, Cambridge, United Kingdom., van der Bolt N; Department of Experimental Immunohematology, Sanquin Research and Landsteiner Laboratory, Amsterdam University Medical Center (AUMC), Amsterdam, The Netherlands., Brown C; Histocompatibility and Immunogenetics Laboratory, NHS Blood and Transplant-Colindale Centre, London, United Kingdom., Brugger K; Computational Biology Unit, Department of Informatics, University of Bergen, Bergen, Norway., Dilthey AT; Institute of Medical Microbiology, University Hospital of Dusseldorf, Dusseldorf, Germany.; Genome Informatics Section, Computational and Statistical Genomics Branch, National Human Genome Research Institute, Bethesda, MD., Duarte D; Department of Haematology, University of Cambridge, Cambridge Biomedical Campus, Cambridge, United Kingdom.; NIHR BioResource, Cambridge University Hospitals, Cambridge Biomedical Campus, Cambridge, United Kingdom., Grimsley S; International Blood Group Reference Laboratory, NHS Blood and Transplant, Bristol, United Kingdom., van den Hurk K; Department of Donor Medicine Research-Donor Studies, Sanquin Research, Amsterdam, The Netherlands., Jongerius JM; National Screening Laboratory, Sanquin Research and Laboratory Services, Sanquin Research, Amsterdam, The Netherlands., Luken J; Department of Diagnostic Immunohematology, Sanquin Diagnostic Services, Amsterdam, The Netherlands., Megy K; Department of Haematology, University of Cambridge, Cambridge Biomedical Campus, Cambridge, United Kingdom.; NIHR BioResource, Cambridge University Hospitals, Cambridge Biomedical Campus, Cambridge, United Kingdom., Miflin G; NHS Blood and Transplant, London, United Kingdom., Nelson CS; Thermo Fisher Scientific, Santa Clara, CA., Prinsze FJ; Department of Donor Medicine Research-Donor Studies, Sanquin Research, Amsterdam, The Netherlands., Sambrook J; Department of Haematology, University of Cambridge, Cambridge Biomedical Campus, Cambridge, United Kingdom.; NIHR BioResource, Cambridge University Hospitals, Cambridge Biomedical Campus, Cambridge, United Kingdom., Simeoni I; Department of Haematology, University of Cambridge, Cambridge Biomedical Campus, Cambridge, United Kingdom.; NIHR BioResource, Cambridge University Hospitals, Cambridge Biomedical Campus, Cambridge, United Kingdom., Sweeting M; British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom.; National Institute for Health Research Blood and Transplant Research Unit in Donor Health and Genomics, University of Cambridge, Cambridge, United Kingdom.; Department of Health Sciences, University of Leicester, Leicester, United Kingdom., Thornton N; International Blood Group Reference Laboratory, NHS Blood and Transplant, Bristol, United Kingdom., Trompeter S; NHS Blood and Transplant, London, United Kingdom.; University College London NHS Foundation Trust, London, United Kingdom., Tuna S; Department of Haematology, University of Cambridge, Cambridge Biomedical Campus, Cambridge, United Kingdom.; NIHR BioResource, Cambridge University Hospitals, Cambridge Biomedical Campus, Cambridge, United Kingdom., Varma R; Thermo Fisher Scientific, Santa Clara, CA., Walker MR; British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom.; National Institute for Health Research Blood and Transplant Research Unit in Donor Health and Genomics, University of Cambridge, Cambridge, United Kingdom., Danesh J; British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom.; National Institute for Health Research Blood and Transplant Research Unit in Donor Health and Genomics, University of Cambridge, Cambridge, United Kingdom.; Health Data Research UK Cambridge, Wellcome Genome Campus and University of Cambridge, Cambridge, United Kingdom.; Department of Human Genetics, Wellcome Sanger Institute, Hinxton, United Kingdom., Roberts DJ; National Institute for Health Research Blood and Transplant Research Unit in Donor Health and Genomics, University of Cambridge, Cambridge, United Kingdom.; NHS Blood and Transplant, Oxford, United Kingdom.; NIHR Oxford Biomedical Research Centre-Haematology Theme and Radcliffe Department of Medicine, University of Oxford, John Radcliffe Hospital, Oxford, United Kingdom., Ouwehand WH; Department of Haematology, University of Cambridge, Cambridge Biomedical Campus, Cambridge, United Kingdom.; NHS Blood and Transplant, Cambridge Biomedical Campus, Cambridge, United Kingdom.; National Institute for Health Research Blood and Transplant Research Unit in Donor Health and Genomics, University of Cambridge, Cambridge, United Kingdom.; Department of Human Genetics, Wellcome Sanger Institute, Hinxton, United Kingdom., Stirrups KE; Department of Haematology, University of Cambridge, Cambridge Biomedical Campus, Cambridge, United Kingdom.; NIHR BioResource, Cambridge University Hospitals, Cambridge Biomedical Campus, Cambridge, United Kingdom., Rendon A; Department of Haematology, University of Cambridge, Cambridge Biomedical Campus, Cambridge, United Kingdom.; Genomics England, London, United Kingdom., Westhoff CM; Immunohematology and Genomics, New York Blood Center, New York., Di Angelantonio E; British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom.; National Institute for Health Research Blood and Transplant Research Unit in Donor Health and Genomics, University of Cambridge, Cambridge, United Kingdom.; Health Data Research UK Cambridge, Wellcome Genome Campus and University of Cambridge, Cambridge, United Kingdom., van der Schoot CE; Department of Experimental Immunohematology, Sanquin Research and Landsteiner Laboratory, Amsterdam University Medical Center (AUMC), Amsterdam, The Netherlands., Astle WJ; NHS Blood and Transplant, Cambridge Biomedical Campus, Cambridge, United Kingdom.; National Institute for Health Research Blood and Transplant Research Unit in Donor Health and Genomics, University of Cambridge, Cambridge, United Kingdom.; MRC Biostatistics Unit, Cambridge Biomedical Campus, Cambridge, United Kingdom., Watkins NA; NHS Blood and Transplant, Cambridge Biomedical Campus, Cambridge, United Kingdom., Lane WJ; Department of Pathology, Brigham and Women's Hospital, Boston, MA; and.; Harvard Medical School, Boston, MA.

Publikováno v: Blood advances [Blood Adv] 2020 Aug 11; Vol. 4 (15), pp. 3495-3506.

Donor InSight: characteristics and representativeness of a Dutch cohort study on blood and plasma donors.

Autor: Timmer TC; Department of Donor Medicine Research - Donor Studies, Sanquin Research, Amsterdam, The Netherlands.; Department of Public Health, Landsteiner Laboratory, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands., de Groot R; Department of Donor Medicine Research - Donor Studies, Sanquin Research, Amsterdam, The Netherlands.; Department of Epidemiology and Biostatistics, Amsterdam Public Health Institute, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands., Habets K; Regional Emergency Healthcare Network, Radboudumc, Nijmegen, The Netherlands., Merz EM; Department of Donor Medicine Research - Donor Studies, Sanquin Research, Amsterdam, The Netherlands.; Department of Sociology, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands., Prinsze FJ; Department of Donor Medicine Research - Donor Studies, Sanquin Research, Amsterdam, The Netherlands., Atsma F; Scientific Institute for Quality of Healthcare, Radboudumc, Nijmegen, the Netherlands., de Kort WLAM; Department of Donor Medicine Research - Donor Studies, Sanquin Research, Amsterdam, The Netherlands.; Department of Public Health, Landsteiner Laboratory, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands., van den Hurk K; Department of Donor Medicine Research - Donor Studies, Sanquin Research, Amsterdam, The Netherlands.

Publikováno v: Vox sanguinis [Vox Sang] 2019 Feb; Vol. 114 (2), pp. 117-128. Date of Electronic Publication: 2018 Dec 27.

Loss of imprinting of IGF2 characterises high IGF2 mRNA-expressing type of fibroblast-like synoviocytes in rheumatoid arthritis.

Autor: Martin-Trujillo A; Department of Pathology, VU University Medical Center, Amsterdam, The Netherlands., van Rietschoten JG, Timmer TC, Rodríguez FM, Huizinga TW, Tak PP, Marsal S, Ibrahim SM, Dijkmans BA, van der Pouw Kraan TC, Verweij CL

Publikováno v: Annals of the rheumatic diseases [Ann Rheum Dis] 2010 Jun; Vol. 69 (6), pp. 1239-42. Date of Electronic Publication: 2009 Jun 24.

Fibroblast-like synoviocytes derived from patients with rheumatoid arthritis show the imprint of synovial tissue heterogeneity: evidence of a link between an increased myofibroblast-like phenotype and high-inflammation synovitis.

Autor: Kasperkovitz PV; VU Medical Center, Amsterdam, The Netherlands., Timmer TC, Smeets TJ, Verbeet NL, Tak PP, van Baarsen LG, Baltus B, Huizinga TW, Pieterman E, Fero M, Firestein GS, van der Pouw Kraan TC, Verweij CL

Publikováno v: Arthritis and rheumatism [Arthritis Rheum] 2005 Feb; Vol. 52 (2), pp. 430-41.