Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Timin Hadi"'
Publikováno v:
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-8 (2020)
Scientific Reports, Vol 10, Iss 1, Pp 1-8 (2020)
The ability to quickly and easily assess the activity of large collections of enzymes for a desired substrate holds great promise in the field of biocatalysis. Cell-free synthesis, although not practically amenable for large-scale enzyme production,
Autor:
Alba Diaz-Rodriguez, Gheorghe-Doru Roiban, Kristin K. Brown, Kathleen T. Gallagher, Timin Hadi, Diluar Khan, Markus Schober, Radka Snajdrova, Douglas E. Fuerst, James Patrick Morrison, Michael R. Webb, Justin M. Kaplan
Publikováno v:
Organic Process Research & Development. 22:871-879
Several biocatalytic approaches for the preparation of optically pure methyl 3-oxocyclohexanecarboxylates (S)-, (R)-1 and 3-oxocyclohexanecarbonitriles (S)-, (R)-2 have been successfully demonstrated. Screening of reaction-focused enzyme collections
Autor:
Marcelo Kern, Kristin K. Brown, Lydia Sanchez Jordan, Gheorghe-Doru Roiban, Pei Lyn Tey, Leigh Anne F. Ihnken, Julia F. Hyslop, Zhi Liu, Murray J. B. Brown, Matthew S. Levine, Timin Hadi
Publikováno v:
ChemCatChem. 9:4475-4479
Chiral secondary and tertiary amines are ubiquitous in pharmaceutical, fine, and specialty chemicals, but their synthesis typically suffers from significant sustainability and selectivity challenges. Biocatalytic alternatives, such as enzyme-catalyze
Publikováno v:
ACS Med Chem Lett
[Image: see text] The use of biocatalysis in the manufacture of small molecule active pharmaceutical ingredients has seen a marked increase over the past decade. Driven by academic and industrial interest in the application of enzymes as catalysts fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d99340139655fc426d94070b3d62adc
https://europepmc.org/articles/PMC6792145/
https://europepmc.org/articles/PMC6792145/
Publikováno v:
Archives of Biochemistry and Biophysics. 540:53-61
Glyceraldehyde 3-phosphate dehydrogenase (GAPDH) is a glycolytic protein responsible for the conversion of glyceraldehyde 3-phosphate (G3P), inorganic phosphate and nicotinamide adenine dinucleotide (NAD(+)) to 1,3-bisphosphoglycerate (1,3-BPG) and t
Publikováno v:
Biochemistry. 52:9286-9293
Isocitrate lyase (ICL) catalyzes the reversible retro-aldol cleavage of isocitrate to generate glyoxylate and succinate. ICL is the first enzyme of the glyoxylate shunt, which allows for the anaplerosis of citric acid cycle intermediates under nutrie
Publikováno v:
Biochemistry. 52:1765-1775
Mycobacterium tuberculosis (Mtb) is the leading cause of death due to a bacterial infection. The success of the Mtb pathogen has largely been attributed to the nonreplicating, persistence phase of the life cycle, for which the glyoxylate shunt is req
Publikováno v:
Biology of Reproduction. 72:179-187
One-cell-stage embryos derived from most random-bred and inbred female mice exhibit an in vitro developmental block at the two-cell stage in classical embryo culture media. However, embryos derived from many F1 hybrids develop easily past the two-cel
Publikováno v:
Biochemistry. 52(51)
The breakdown and recycling of peptidoglycan, an essential polymeric cell structure, occurs in a number of bacterial species. A key enzyme in the recycling pathway of one of the components of the peptidoglycan layer, N-acetylmuramic acid (MurNAc), is
Publikováno v:
The Journal of organic chemistry. 76(4)
Peptidoglycan is the component of the bacterial cell wall that is essential for maintaining the shape and rigidity of the cell. As such, its polymeric structure, consisting of alternating units of N-acetylglucosamine (GlcNAc) and N-acetylmuramic acid