Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Timara Kuiper"'
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 11 (2024)
ObjectiveEndothelial-to-mesenchymal transition (EndMT) is a transdifferentiation process in which endothelial cells (ECs) adopt a mesenchymal-like phenotype. Over the past few years, it became clear that EndMT can contribute to several cardiovascular
Externí odkaz:
https://doaj.org/article/0b13d1cee3e243abb4ca3d435ef523ed
Autor:
Sophie F. Ellermann, Rianne M. Jongman, Matthijs Luxen, Timara Kuiper, Josee Plantinga, Jill Moser, Thomas W. L. Scheeren, Gregor Theilmeier, Grietje Molema, Matijs Van Meurs
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Major surgery induces systemic inflammation leading to pro-inflammatory activation of endothelial cells. Endothelial inflammation is one of the drivers of postoperative organ damage, including acute kidney injury Tumour Necrosis Factor alpha (TNF-α)
Externí odkaz:
https://doaj.org/article/cf25c4bc3adc4a79a97601512bf31bd1
Autor:
Peter J. Zwiers, Rianne M. Jongman, Timara Kuiper, Jill Moser, Radu V. Stan, Joachim R. Göthert, Matijs van Meurs, Eliane R. Popa, Grietje Molema
Publikováno v:
PLoS ONE, Vol 17, Iss 6 (2022)
Tyrosine-protein kinase receptor Tie2, also known as Tunica interna Endothelial cell Kinase or TEK plays a prominent role in endothelial responses to angiogenic and inflammatory stimuli. Here we generated a novel inducible Tie2 knockout mouse model,
Externí odkaz:
https://doaj.org/article/87343e3da24d4f7fb9bde788a5e7c178
Autor:
Susanna Skalicky, Peter J Zwiers, Timara Kuiper, Elisabeth Schraml, Matthias Hackl, Grietje Molema
Publikováno v:
BioTechniques, Vol 67, Iss 6, Pp 276-285 (2019)
Neglecting tissue heterogeneity during the analysis of microRNA (miRNA) levels results in average signals from an unknown mixture of different cell types that are difficult to interpret. Here we demonstrate the technical requirements needed to obtain
Externí odkaz:
https://doaj.org/article/6ede8c10699f4dd4a558f7dcfd18bd3e
Autor:
Erna-Zulaikha Dayang, Matthijs Luxen, Timara Kuiper, Rui Yan, Savithri Rangarajan, Matijs van Meurs, Jill Moser, Grietje Molema
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 133, Iss , Pp 111073- (2021)
Sepsis is a life-threatening condition often leading to multiple organ failure for which currently no pharmacological treatment is available. Endothelial cells (EC) are among the first cells to respond to pathogens and inflammatory mediators in sepsi
Externí odkaz:
https://doaj.org/article/99cbdd3d773b4c3fb3f1e9ea53e191f4
Autor:
Elisabeth Schraml, Matthias Hackl, Peter J. Zwiers, Grietje Molema, Timara Kuiper, Susanna Skalicky
Publikováno v:
Biotechniques, 67(6), 276-285. FUTURE SCI LTD
Neglecting tissue heterogeneity during the analysis of microRNA (miRNA) levels results in average signals from an unknown mixture of different cell types that are difficult to interpret. Here we demonstrate the technical requirements needed to obtain
Autor:
Peter J. Zwiers, Rianne M. Jongman, Timara Kuiper, Jill Moser, Radu V. Stan, Joachim R. Göthert, Matijs van Meurs, Eliane R. Popa, Grietje Molema
Publikováno v:
PLoS ONE, 17(6):e0268986. PUBLIC LIBRARY SCIENCE
Tyrosine-protein kinase receptor Tie2, also known as Tunica interna Endothelial cell Kinase or TEK plays a prominent role in endothelial responses to angiogenic and inflammatory stimuli. Here we generated a novel inducible Tie2 knockout mouse model,
Autor:
Rui Yan, Matijs van Meurs, Timara Kuiper, Matthijs Luxen, Savithri Rangarajan, Erna-Zulaikha Dayang, Jill Moser, Grietje Molema
Publikováno v:
Biomedicine & Pharmacotherapy, 133:111073. ELSEVIER FRANCE-EDITIONS SCIENTIFIQUES MEDICALES ELSEVIER
Biomedicine & Pharmacotherapy, Vol 133, Iss, Pp 111073-(2021)
Biomedicine & Pharmacotherapy, Vol 133, Iss, Pp 111073-(2021)
Sepsis is a life-threatening condition often leading to multiple organ failure for which currently no pharmacological treatment is available. Endothelial cells (EC) are among the first cells to respond to pathogens and inflammatory mediators in sepsi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4fc14b98b448ca3945b85465e15e1ae
https://research.rug.nl/en/publications/f17e6853-408a-4c87-ad25-21038ef08611
https://research.rug.nl/en/publications/f17e6853-408a-4c87-ad25-21038ef08611
Autor:
Matijs van Meurs, Peter Heeringa, Grietje Molema, Jan G. Zijlstra, Jan A. A. M. Kamps, Rianne M. Jongman, Anita E. Niemarkt, Eliane R. Popa, Timara Kuiper, Peter J. Zwiers, Jill Moser, Rui Yan
Publikováno v:
Journal of Innate Immunity. 9:546-560
Sepsis is a severe systemic inflammatory response to infection. Endothelial activation and dysfunction play a critical role in the pathophysiology of sepsis and represent an important therapeutic target to reduce sepsis mortality. Interferon regulato
Autor:
Adinda Bisschop, Lidia P. Sashchenko, Sander de Kivit, Kirsten J. Koymans, Jianhong Lu, Andreas Beineke, Jian Ma, Satz Mengensatzproduktion, Ke Li, Heping Xu, Johanna Klemens, Veronica Ayechu Muruzabal, Oliver Goldmann, Ying Zheng, Natalia V. Soshnikova, Xuemei Zhang, Xia Dong, Wiedjai Sital, Kok P. M. van Kessel, Yizhi Liu, Lingyu Wei, Mohajeet B. Bhuckory, Qiurong Ye, Matijs van Meurs, Eliane R. Popa, Weiju Wu, Chengfei Liu, Mary E. Morgan, Atanaska I. Kostadinova, Jill Moser, Johan Garssen, Anita E. Niemarkt, Eva Medina, Olga K. Ivanova, Peter J. Zwiers, Manouk Vrieling, Jos A. G. van Strijp, Chunlin Ou, Jan G. Zijlstra, Wuding Zhou, Carla J. C. de Haas, Léon M.J. Knippels, Jan A. Kamps, Druckerei Stückle, JoAnn Kerperien, Jia Wang, Xiang Zheng, Ulrike Blaschke, Peter Heeringa, Zailong Qin, Liang Ma, Rianne M. Jongman, Guiyuan Li, Denis V. Yashin, Rui Yan, Qun Yan, Emeline F. Nandrot, Elena A. Romanova, Linette E M Willemsen, Yuanjun Lu, Liping Wang, Tatiana N. Sharapova, Aletta D. Kraneveld, Christofer Karlsson, Robert Thänert, Grietje Molema, Qiu Peng, Yuxin Fu, Timara Kuiper, Johan Malmström, Wei Xiong
Publikováno v:
Journal of Innate Immunity. 9:I-IV