Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Timao Li"'
Publikováno v:
Molecular and Cellular Biochemistry. 251:9-15
Increased oxidative stress and reduction in antioxidant enzymes have been suggested to be involved in the pathophysiology of congestive heart failure subsequent to myocardial infarction (MI). The objective of the present study was to characterize cha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f5310e055f123b0b9c2960048041399a
https://doi.org/10.1023/a:1025448908694
https://doi.org/10.1023/a:1025448908694
Publikováno v:
Molecular and Cellular Biochemistry. 232:19-26
Increased oxidative stress and antioxidant deficit have been suggested to play a major role in adriamycin-induced cardiomyopathy and congestive heart failure due to multiple treatments with adriamycin (doxorubicin). In this study, we investigated the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ac3805f893ae611fca442b359c912382
https://doi.org/10.1023/a:1014862912783
https://doi.org/10.1023/a:1014862912783
Publikováno v:
Toxicology. 155:17-26
Metallothioneins (MTs) discovered four decades ago as metal binding low molecular weight thiol proteins, in recent years, have generated immense interest due to their involvement in various physiological and pathophysiological events. In spite of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91b023031249536ca288edbd8d574a01
https://doi.org/10.1016/s0300-483x(00)00273-0
https://doi.org/10.1016/s0300-483x(00)00273-0
Autor:
Pawan K. Singal, Timao Li
Publikováno v:
Circulation. 102:2105-2110
Background —The clinical usefulness of adriamycin is restricted by the development of congestive heart failure. It has been suggested that probucol, a strong antioxidant, completely prevents adriamycin-induced cardiomyopathy without interfering wit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65480a6c0f3e1068dbecd1e48528d258
https://doi.org/10.1161/01.cir.102.17.2105
https://doi.org/10.1161/01.cir.102.17.2105
Publikováno v:
Molecular and Cellular Biochemistry. 207:77-86
Adriamycin (doxorubicin) is one of the most effective chemotherapeutic agents against a variety of cancers, but its usefulness is seriously curtailed by the risk of developing heart failure. Available laboratory evidence suggests that an increase in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e11474ec291e1a63be6009c0bd8b383d
https://doi.org/10.1023/a:1007094214460
https://doi.org/10.1023/a:1007094214460
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 277:H2124-H2128
The deficiency of methionine, an essential amino acid, is associated with cardiovascular lesions. Because different types of cardiac pathologies are caused by a decrease in antioxidants, we examined the effects of methionine on myocardial antioxidant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::818001ddab282ab3ac9b169c1c209cec
https://doi.org/10.1152/ajpheart.1999.277.6.h2124
https://doi.org/10.1152/ajpheart.1999.277.6.h2124
Publikováno v:
The FASEB Journal. 11:931-936
Current knowledge about adriamycin cardiomyopathy indicates that the major cause of this condition is increased oxidative stress although the drug's antitumor action in patients may involve other mechanisms. Controversies about the different antioxid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca1154b7668b95e1fc120c9d31995172
https://doi.org/10.1096/fasebj.11.12.9337145
https://doi.org/10.1096/fasebj.11.12.9337145
Publikováno v:
Experimental and clinical cardiology. 8(2)
Recently, drug interactions with grapefruit juice (GFJ) have received considerable attention from basic scientists, physicians, industry and drug regulatory agencies. GFJ has been shown to inhibit cytochrome P-450 3A4 isoenzyme and P-glycoprotein tra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9352a920f06a9a3d94391715955a009b
https://pubmed.ncbi.nlm.nih.gov/19641658
https://pubmed.ncbi.nlm.nih.gov/19641658
Publikováno v:
Experimental and clinical cardiology. 10(4)
Hypertension, myocardial infarction, atherosclerosis, arrhythmias and valvular heart disease, coagulopathies and stroke, collectively known as cardiovascular diseases (CVDs), contribute greatly to the mortality, morbidity and economic burden of illne
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e5c464b68599b329c1c1f4edd281e1b5
https://pubmed.ncbi.nlm.nih.gov/19641674
https://pubmed.ncbi.nlm.nih.gov/19641674
Publikováno v:
Molecular and cellular biochemistry. 232(1-2)
Increased oxidative stress and antioxidant deficit have been suggested to play a major role in adriamycin-induced cardiomyopathy and congestive heart failure due to multiple treatments with adriamycin (doxorubicin). In this study, we investigated the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2b4d6bd82ac1398aec3bcf51fcf2d8c6
https://pubmed.ncbi.nlm.nih.gov/12030376
https://pubmed.ncbi.nlm.nih.gov/12030376