Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Tim van Zutphen"'
Autor:
Brian M. Doornenbal, Tim van Zutphen, Lise F. E. Beumeler, Rimke C. Vos, Mark Derks, Hinke Haisma, M. Elske van den Akker-van Marle, Jessica C. Kiefte-de Jong
Publikováno v:
Journal of Patient-Reported Outcomes, Vol 8, Iss 1, Pp 1-15 (2024)
Abstract Background The concept of Positive Health (PH) has gained increasing attention as a way of measuring individuals’ ability to adapt in the face of contextual challenges. However, a suitable measurement instrument for PH that encompasses con
Externí odkaz:
https://doaj.org/article/2d9b429567a44ec7a6979ae9217e68aa
Autor:
Jiufang Yang, Theo H. van Dijk, Martijn Koehorst, Rick Havinga, Jan Freark de Boer, Folkert Kuipers, Tim van Zutphen
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 4, p 4132 (2023)
Bile acids facilitate the intestinal absorption of dietary lipids and act as signalling molecules in the maintenance of metabolic homeostasis. Farnesoid X receptor (FXR) is a bile acid-responsive nuclear receptor involved in bile acid metabolism, as
Externí odkaz:
https://doaj.org/article/8fe97708e815448d809de3a14f82fda1
Autor:
Lise F E Beumeler, Anja van Wieren, Hanneke Buter, Tim van Zutphen, Gerjan J Navis, E Christiaan Boerma
Publikováno v:
PLoS ONE, Vol 17, Iss 9, p e0273348 (2022)
PurposeMore substantial information on recovery after Intensive Care Unit (ICU) admission is urgently needed. In a previous retrospective study, the proportion of non-recovery patients was 44%. The aim of this prospective follow-up study was to evalu
Externí odkaz:
https://doaj.org/article/740ed2eca3d048a6a20f0ca942cb907b
Autor:
Tim van Zutphen, Johanna H.M. Stroeve, Jiufang Yang, Vincent W. Bloks, Angelika Jurdzinski, Han Roelofsen, Nicolette C.A. Huijkman, Theo H. van Dijk, Roel J. Vonk, Jan van Deursen, Bart Staels, Albert K. Groen, Folkert Kuipers
Publikováno v:
Journal of Lipid Research, Vol 60, Iss 9, Pp 1547-1561 (2019)
The bile acid-activated nuclear receptor, FXR (NR1H4), has been implicated in the control of lipid and energy metabolism, but its role in fat tissue, where it is moderately expressed, is not understood. In view of the recent development of FXR-target
Externí odkaz:
https://doaj.org/article/8840b252e57a440b90ac25aad4d7f14e
Autor:
Lise F E Beumeler, Anja van Wieren, Hanneke Buter, Tim van Zutphen, Nynke A Bruins, Corine M de Jager, Matty Koopmans, Gerjan J Navis, E Christiaan Boerma
Publikováno v:
PLoS ONE, Vol 15, Iss 12, p e0243981 (2020)
Post-intensive care unit (ICU) sequelae, including physical and mental health problems, are relatively unexplored. Characteristics commonly used to predict outcome lack prognostic value when it comes to long-term physical recovery. Therefore, the obj
Externí odkaz:
https://doaj.org/article/d6e00f9a38d442779accb57f5c9df730
Autor:
Marcela Doktorova, Irene Zwarts, Tim van Zutphen, Theo H. van Dijk, Vincent W. Bloks, Liesbeth Harkema, Alain de Bruin, Michael Downes, Ronald M. Evans, Henkjan J. Verkade, Johan W. Jonker
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-10 (2017)
Abstract Peroxisome proliferator-activated receptor δ (PPARδ) is a ligand-activated transcription factor that has an important role in lipid metabolism. Activation of PPARδ stimulates fatty acid oxidation in adipose tissue and skeletal muscle and
Externí odkaz:
https://doaj.org/article/adc9aeb287f8410a912102df98040a2d
Autor:
Beorn Nijenhuis, Marina A.J. Tijssen, Tim van Zutphen, Jan Willem Elting, Aron H.P. Schalkwijk, Egbert Otten, Jeroen van der Eb
Publikováno v:
Clinical Neurophysiology. 149:113-120
Objective: Skater's cramp is a movement disorder in speed skaters. We investigated whether affected skaters matched the disease profile of task-specific dystonia, specifically whether there was evidence of maladaptive muscle activity occurring simult
Autor:
Edith Visser, Kim de Jong, Janneke J. S. Pepels, Huib A. M. Kerstjens, Anneke ten Brinke, Tim van Zutphen
Publikováno v:
European Journal of Nutrition. 62:1635-1645
Purpose Dietary factors have been suggested as drivers of the rising prevalence of adult-onset asthma, but evidence is inconclusive, possibly due to the complex interrelation with obesity. We aim to explore the relation of diet quality and food intak
Autor:
Hilde D. de Vries, Anna Palmiotti, Rumei Li, Milaine V. Hovingh, Niels L. Mulder, Martijn Koehorst, Vincent W. Bloks, Tim van Zutphen, Folkert Kuipers, Jan Freark de Boer
Publikováno v:
Pediatric Research. Nature Publishing Group
Background Cyp2c70-/- mice with a human-like bile acid (BA) composition display features of neonatal cholestasis. We assessed whether perinatal ursodeoxycholic acid (UDCA) exposure prevents neonatal cholestasis in Cyp2c70-/- mice and reduces cholangi
Autor:
Dionne Sizoo, Suzanne P. Stam, Loek J.M. de Heide, Marloes Emous, Tim van Zutphen, Peter R. van Dijk, André P. van Beek
Publikováno v:
Diabetes Research and Clinical Practice, 195:110197. ELSEVIER IRELAND LTD
Objective: The aim of this study is to investigate whether muscle mass is associated with the prevalence and incidence of type 2 diabetes and whether this association differs within men and women of normal weight, overweight or obesity. Methods: Adul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed2f5e82494395f69509eed9b944f773
https://research.rug.nl/en/publications/94211ffc-4dcd-40d5-b61f-97fef595820e
https://research.rug.nl/en/publications/94211ffc-4dcd-40d5-b61f-97fef595820e