Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Tim van Beers"'
Autor:
Xin Shi, Panpan Li, Marc Herb, Hanhan Liu, Maoren Wang, Xiaosha Wang, Yuan Feng, Tim van Beers, Ning Xia, Huige Li, Verena Prokosch
Publikováno v:
Journal of Neuroinflammation, Vol 21, Iss 1, Pp 1-23 (2024)
Abstract Background NADPH oxidase (NOX), a primary source of endothelial reactive oxygen species (ROS), is considered a key event in disrupting the integrity of the blood-retinal barrier. Abnormalities in neurovascular-coupled immune signaling herald
Externí odkaz:
https://doaj.org/article/8cefb59a93cf49a6b18fe067964ea100
Autor:
Salh Nawshirwan, Nicole Heucken, Nadin Piekarek, Tim van Beers, Nicole Fulgham-Scott, Andrea Grandoch, Wolfram F. Neiss, Johannes Vogt, Mohammed Barham
Publikováno v:
Frontiers in Veterinary Science, Vol 10 (2023)
IntroductionSarcocystis is a genus of cyst-forming parasites that infest both humans and livestock. Some parasites cause clinical and subclinical diseases in their hosts, resulting in economic losses.MethodsEsophagus, diaphragm, and skeletal muscle f
Externí odkaz:
https://doaj.org/article/6cdc68d98e1c4e5d99b9cf80ebda1d3a
Publikováno v:
Antioxidants, Vol 11, Iss 10, p 1864 (2022)
Research has been conducted into vascular abnormalities in the pathogenesis of glaucoma, but conclusions remain controversial. Our aim was to test the hypothesis that retinal endothelial dysfunction induced by elevated intraocular pressure (IOP) pers
Externí odkaz:
https://doaj.org/article/0b6534a33b69490894f4524d79362dcc
Autor:
Laura-Marie A. Zimmermann, Ariane G. Furlan, Dennis Mehrkens, Simon Geißen, Alexandra V. Zuk, Galyna Pryymachuk, Nadine Pykarek, Tim van Beers, Dagmar Sonntag-Bensch, Julia Marzi, Katja Schenke-Layland, Jürgen Brinckmann, Paola Zigrino, Maria Grandoch, Stephan Baldus, Gerhard Sengle
Fibrillin-1 assembles into microfibrils that not only define the structural integrity and biomechanics of the aorta but also target and sequester growth factors within the extracellular microenvironment of aortic resident cells. To better understand
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c40401708e9a458b3c61dcb2572801ab
https://doi.org/10.1101/2022.11.30.518511
https://doi.org/10.1101/2022.11.30.518511
Autor:
Nicholas Hanuscheck, Carine Thalman, Micaela Domingues, Samantha Schmaul, Muthuraman Muthuraman, Florian Hetsch, Manuela Ecker, Heiko Endle, Mohammadsaleh Oshaghi, Gianvito Martino, Tanja Kuhlmann, Katarzyna Bozek, Tim van Beers, Stefan Bittner, Jakob von Engelhardt, Johannes Vogt, Christina Francisca Vogelaar, Frauke Zipp
Publikováno v:
Journal of Experimental Medicine. 219
Evidence is emerging that immune responses not only play a part in the central nervous system (CNS) in diseases but may also be relevant for healthy conditions. We discovered a major role for the interleukin-4 (IL-4)/IL-4 receptor alpha (IL-4Rα) sig
Autor:
Wilhelm Bloch, Jörg Dötsch, Mojgan Ghilav, Tobias Kretschmer, Eva Hucklenbruch-Rother, Eva-Maria Turnwald, Peter Zentis, Tim van Beers, Maria Wohlfarth, Sarah Appel, Marion Handwerk, Inga Bae-Gartz, Ruth Janoschek
Publikováno v:
Biology of Reproduction. 103:1260-1274
Evidence suggests that maternal obesity (MO) can aggravate placental function causing severe pathologies during the perinatal window. However, molecular changes and mechanisms of placental dysfunction remain largely unknown. This work aimed to deciph
Autor:
Maoren Wang, Yue Ruan, Marianne B. Müller, Tim van Beers, Karl Mercieca, Verena Prokosch, Harald von Pein, Marija Milic, Adrian Gericke, Hanhan Liu, Subao Jiang
Publikováno v:
Experimental Eye Research. 213:108853
Purpose The roles of vascular dysfunction and chronic stress have been extensively discussed in the pathophysiology of glaucoma. Our aim was to test whether chronic stress causes retinal vascular dysfunction and therewith induces retinal ganglion cel