Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Tim den Hartog"'
Autor:
Francesc Sastre, Caroline Versluis, Nicole Meulendijks, Jessica Rodríguez-Fernández, Jorgen Sweelssen, Ken Elen, Marlies K. Van Bael, Tim den Hartog, Marcel A. Verheijen, Pascal Buskens
Publikováno v:
ACS Omega, Vol 4, Iss 4, Pp 7369-7377 (2019)
Externí odkaz:
https://doaj.org/article/b39a171f7d354cc1aa37e7429c76e422
Autor:
Elena Geiser, Nick Wierckx, Walter Leitner, Linda Büttner, Lars M. Blank, Eda Sarikaya, Jürgen Klankermayer, Wiebke Kleineberg, Sandra Przybilla, Meike Engel, Michael Bölker, Tim den Hartog
Publikováno v:
Metabolic Engineering. 38:427-435
The Ustilaginaceae family of smut fungi, especially Ustilago maydis, gained biotechnological interest over the last years, amongst others due to its ability to naturally produce the versatile bio-based building block itaconate. Along with itaconate,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4cc701d1dcc509a89a8d107ddf30957
https://doi.org/10.1016/j.ymben.2016.10.006
https://doi.org/10.1016/j.ymben.2016.10.006
Publikováno v:
Israel Journal of Chemistry. 56:53-61
A case study in the (re)discovery of a non-diazo, catalytic, electrophilic cyclopropanation reaction is presented to illustrate the role of mechanistic concepts in chemical innovation. The specific instance also highlights how specific personalities
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3adfabd14be14dcc3dfdb0a4691b7186
https://doi.org/10.1002/ijch.201500041
https://doi.org/10.1002/ijch.201500041
Publikováno v:
Angewandte Chemie. 127:10817-10821
Nickel wurde als Katalysator fur die Cyclopropanierung von unaktivierten Olefinen durch in situ hergestelltes Lithiomethyltrimethylammoniumtriflat als Methylendonor identifiziert. Eine mechanistische Hypothese wird vorgeschlagen, welche die Entstehun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1ff0af23a98c586aa0710070c452ec89
https://doi.org/10.1002/ange.201505482
https://doi.org/10.1002/ange.201505482
Autor:
Thorsten vom Stein, Tim den Hartog, Julien Buendia, Spas Stoychev, Jakob Mottweiler, Carsten Bolm, Jürgen Klankermayer, Walter Leitner
Publikováno v:
Angewandte Chemie. 127:5957-5961
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bb9a6da51032576738c72d700251df0f
https://doi.org/10.1002/ange.201410620
https://doi.org/10.1002/ange.201410620
Autor:
Martín Fañanás-Mastral, Yange Huang, Manuel Perez, Alena Rudolph, Anne M. Meuwese, Ben L. Feringa, Tim den Hartog, Adriaan J. Minnaard
Publikováno v:
ACS Catalysis, 5(2), 560-574. AMER CHEMICAL SOC
The enantioselective 1,6-addition to unsaturated carbonyl compounds otters unique opportunities to study the range of selectivities one can obtain using Cu catalysis. Here, a substrate-reagent approach to obtain structural information on the mechanis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b81614179be79653a595f975fe80fe2b
https://research.rug.nl/en/publications/dca1ecb2-a8fe-408b-9110-09f4308b7ba2
https://research.rug.nl/en/publications/dca1ecb2-a8fe-408b-9110-09f4308b7ba2
Publikováno v:
Organic letters
Methylenation of electron-rich olefins is a highly challenging reaction, for which we have developed a new methodology exploiting Pd-catalysis and halomethylboronate reagents, the latter replacing diazomethane and zinc carbenoids as methylene donors.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba9906c4ac30fd2d1abd1d0c5dfb6bca
https://doi.org/10.1021/ol403695b
https://doi.org/10.1021/ol403695b
Publikováno v:
Chemical communications
Straightforward deprotonation of soluble tetramethylammonium salts with alkyllithium reagents gives lithiomethyl trimethylammonium reagents. Coordination of the Li cation is crucial to the stability of these ‘N–C ylides’. These reagents were us
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ef494af3c4c0418f9a0fcb234eb5bea
Publikováno v:
ChemInform. 47
The title reaction is performed on unactivated alkenes, including cycloalkenes and 1-substituted alkenes, but fails using α-pinene or 3,4-dihydro-2H-pyrane.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::082d1864631ff870fd567f9679d0001e
https://doi.org/10.1002/chin.201602041
https://doi.org/10.1002/chin.201602041
Publikováno v:
Advanced Synthesis & Catalysis, 352(6), 999-1013. WILEY-V C H VERLAG GMBH
The highly enantioselective synthesis of a- methyl-substituted esters is reported in up to 90% yield and up to 99% ee using copper-TaniaPhos as chiral catalyst. The transformation proved scalable to at least 6.6 mmol (1.7 g scale). The products of th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::deffbc70b1edfd3e73bb152cb486fba2
https://doi.org/10.1002/adsc.201000109
https://doi.org/10.1002/adsc.201000109