Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Tim Worbs"'
Autor:
Rieke Martens, Marc Permanyer, Kathrin Werth, Kai Yu, Asolina Braun, Olga Halle, Stephan Halle, Gwendolyn E. Patzer, Berislav Bošnjak, Friedemann Kiefer, Anika Janssen, Michaela Friedrichsen, Jenny Poetzsch, Karan Kohli, Yvonne Lueder, Rodrigo Gutierrez Jauregui, Nadine Eckert, Tim Worbs, Melanie Galla, Reinhold Förster
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
Immune cells mostly enter lymph nodes (LN) from blood circulation, but whether afferent lymphatics contributes to LN entry is unclear. Here, the authors show, using a photo-convertible reporter, that T cells in afferent lymphatics frequently enter LN
Externí odkaz:
https://doaj.org/article/b8963b2416da4786a23a0db5ee2b12ab
Autor:
Moritz Kleine, Tim Worbs, Harald Schrem, Florian W R Vondran, Alexander Kaltenborn, Jürgen Klempnauer, Reinhold Förster, Christine Josenhans, Sebastian Suerbaum, Hüseyin Bektas
Publikováno v:
PLoS ONE, Vol 9, Iss 6, p e99713 (2014)
Helicobacter hepaticus can lead to chronic hepatitis and hepatocellular carcinoma in certain strains of mice. Until now the pathogenic role of Helicobacter species on human liver tissue is still not clarified though Helicobacter species identificatio
Externí odkaz:
https://doaj.org/article/e18d58d5fb594c5f8ec5c27e2eca840c
Autor:
Nicolas Kurpiers, Tim Worbs, Kai Lindkamp, Tanja Schwier, Anja Nieder, Alexander Pohl, Tim Vogler, Konstantin A. Krauth
Publikováno v:
Archives of Physical Health and Sports Medicine. 1:46-55
Publikováno v:
Nature Reviews Immunology. 17:30-48
Dendritic cells (DCs) are potent and versatile antigen-presenting cells, and their ability to migrate is key for the initiation of protective pro-inflammatory as well as tolerogenic immune responses. Recent comprehensive studies have highlighted the
Autor:
Annika Reinhardt, Siegfried Weiss, Tim Worbs, Tetyana Yevsa, Linda Oberdörfer, Stefan Lienenklaus, Inga Sandrock, Immo Prinz, Reinhold Förster, Thomas Korn
Publikováno v:
Arthritis & Rheumatology. 68:2476-2486
Objective The spondyloarthritides (SpA) are a group of rheumatic diseases characterized by ossification and inflammation of entheseal tissue, the region where tendon attaches to bone. Interleukin-23 (IL-23) is involved in the pathogenesis of SpA by a
Publikováno v:
Immunity. 44(1):9-11
Chemokine receptors are known to signal through heterotrimeric G proteins. In this issue, Hauser et al. (2016) report that inflammatory cues can induce tetramers of the chemokine receptor CCR7 that serve as scaffolds integrating G protein with Src ki
Autor:
Annegret Reinhold, Xiaoqian Wang, Bernhard Meineke, Tim Worbs, Friedemann Kiefer, Christian Freund, Janine Degen, Burkhart Schraven, Markus Moser, Irene Patzak, Mauro Togni, Reinhold Förster, Stefanie Kliche
Publikováno v:
Blood; Vol 119
Blood
Blood
The β2-integrin lymphocyte function-associated antigen-1 (LFA-1) plays a crucial role within the immune system. It regulates the interaction between T cells and antigen-presenting cells and facilitates T-cell adhesion to the endothelium, a process t
Autor:
Annika, Reinhardt, Tetyana, Yevsa, Tim, Worbs, Stefan, Lienenklaus, Inga, Sandrock, Linda, Oberdörfer, Thomas, Korn, Siegfried, Weiss, Reinhold, Förster, Immo, Prinz
Publikováno v:
Arthritisrheumatology (Hoboken, N.J.). 68(10)
The spondyloarthritides (SpA) are a group of rheumatic diseases characterized by ossification and inflammation of entheseal tissue, the region where tendon attaches to bone. Interleukin-23 (IL-23) is involved in the pathogenesis of SpA by acting on I
Autor:
Jasmin Bölter, Stephan Halle, Tim Worbs, Katharina Hoffmann, Anika Münk, Asolina Braun, Reinhold Förster, G. Leandros Moschovakis
Publikováno v:
Nature Immunology. 12:879-887
Little is known about the molecular mechanisms that determine the entry into the lymph node and intranodal positioning of lymph-derived cells. By injecting cells directly into afferent lymph vessels of popliteal lymph nodes, we demonstrate that lymph
Autor:
Verena Thies, Sebastian Seth, Rebecca Hyde, Reinhold Förster, Linda Oberdörfer, Kirstin Hoff, Susanne Schmitz, Tim Worbs
Publikováno v:
The Journal of Immunology. 186:3364-3372
The chemokine receptor CCR7 represents an important determinant for circulating lymphocytes to enter lymph nodes (LN) via high endothelial venules. High endothelial venules also represent the major site of entry for plasmacytoid dendritic cells (pDC)