Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Tim Wesser"'
Autor:
Ye Zhu, Maximilian Blum, Uwe Hoff, Tim Wesser, Mandy Fechner, Christina Westphal, Dennis Gürgen, Rusan Ali Catar, Aurelie Philippe, Kaiyin Wu, Gordana Bubalo, Michael Rothe, Steven M Weldon, Duska Dragun, Wolf-Hagen Schunck
Publikováno v:
PLoS ONE, Vol 11, Iss 1, p e0145645 (2016)
AIM:20-hydroxyeicosatetraenoic acid (20-HETE) and epoxyeicosatrienoic acids (EETs) are cytochrome P450 (CYP)-dependent eicosanoids that play opposite roles in the regulation of vascular tone, inflammation, and apoptosis. 20-HETE aggravates, whereas E
Externí odkaz:
https://doaj.org/article/bf252068991546c0a8d08f0a533dd4f6
Autor:
Adeniyi Michael, Adebesin, Tim, Wesser, Jonnalagadda, Vijaykumar, Anne, Konkel, Mahesh P, Paudyal, Janine, Lossie, Chen, Zhu, Christina, Westphal, Narender, Puli, Robert, Fischer, Wolf-Hagen, Schunck, John R, Falck
Publikováno v:
Journal of medicinal chemistry. 62(22)
17(
Autor:
Narender Puli, Tim Wesser, Janine Lossie, Jonnalagadda Vijaykumar, John R. Falck, Christina Westphal, Wolf-Hagen Schunck, Adeniyi Michael Adebesin, Chen Zhu, Anne Konkel, Robert Fischer, Mahesh P. Paudyal
Publikováno v:
Journal of Medicinal Chemistry.
17(R),18(S)-Epoxyeicosatetraenoic acid (EEQ) is a cytochrome P450 metabolite of eicosapentaenoic acid (EPA) and a powerful negative chronotrope with low nanomolar activity in a neonatal rat cardiomyocyte (NRCM) arrhythmia model. Prior studies identif
Autor:
Christina Westphal, Natalia Alenina, Tim Wesser, Bastian Spallek, Anne Konkel, Michael Bader, Dominik N Müller, Wolf-Hagen Schunck
Publikováno v:
Hypertension. 60
Alterations in cytochrome P450 (CYP)-dependent formation of 20-hydroxyeicosatetraenoic acid (20-HETE) are associated with hypertension and end-organ damage. The cause-and-effect relationships are only partially understood and difficult to dissect due