Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Tim W. Böttger"'
Autor:
Mark Schmitt, Fatih Ceteci, Jalaj Gupta, Marina Pesic, Tim W. Böttger, Adele M. Nicolas, Kilian B. Kennel, Esther Engel, Matthias Schewe, Asude Callak Kirisözü, Valentina Petrocelli, Yasamin Dabiri, Julia Varga, Mallika Ramakrishnan, Madina Karimova, Andrea Ablasser, Toshiro Sato, Melek C. Arkan, Frederic J. de Sauvage, Florian R. Greten
Publikováno v:
Nature
Solid cancers exhibit a dynamic balance between cell death and proliferation ensuring continuous tumour maintenance and growth(1,2). Increasing evidence links enhanced cancer cell apoptosis to paracrine activation of cells in the tumour microenvironm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a15b5f6102e61823c51a5240859270f
https://europepmc.org/articles/PMC7613947/
https://europepmc.org/articles/PMC7613947/
Autor:
Claire Conche, Fabian Finkelmeier, Marina Pešić, Adele M Nicolas, Tim W Böttger, Kilian B Kennel, Dominic Denk, Fatih Ceteci, Kathleen Mohs, Esther Engel, Özge Canli, Yasamin Dabiri, Kai-Henrik Peiffer, Stefan Zeuzem, Gabriela Salinas, Thomas Longerich, Huan Yang, Florian R Greten
Publikováno v:
Gut. :gutjnl-2022
ObjectiveInvestigating the effect of ferroptosis in the tumour microenvironment to identify combinatory therapy for liver cancer treatment.DesignGlutathione peroxidase 4 (GPx4), which is considered the master regulator of ferroptosis, was genetically