Zobrazeno 1 - 10
of 112
pro vyhledávání: '"Tim Tully"'
Neuropeptide F inhibits dopamine neuron interference of long-term memory consolidation in Drosophila
Autor:
Kuan-Lin Feng, Ju-Yun Weng, Chun-Chao Chen, Mohammed Bin Abubaker, Hsuan-Wen Lin, Ching-Che Charng, Chung-Chuan Lo, J. Steven de Belle, Tim Tully, Cheng-Chang Lien, Ann-Shyn Chiang
Publikováno v:
iScience, Vol 24, Iss 12, Pp 103506- (2021)
Summary: Long-term memory (LTM) formation requires consolidation processes to overcome interfering signals that erode memory formation. Olfactory memory in Drosophila involves convergent projection neuron (PN; odor) and dopaminergic neuron (DAN; rein
Externí odkaz:
https://doaj.org/article/cf69f5907c0e4ed6a3bfe10fc136abb1
Autor:
Tim Tully
Publikováno v:
Journal of New Librarianship, Vol 3, Iss 1 (2020)
The growth of the freelance economy has changed the overall business landscape aswell as the landscape of the overall labor force, and these changes have led to the proliferation of co-workingand shared workspaces. Public business librarians can enga
Externí odkaz:
https://doaj.org/article/237307dc1e8347caad9abf215ae3bb82
Autor:
Alex Yen-Yu Chen, Tim Tully
Publikováno v:
Neurobiology of Disease, Vol 114, Iss , Pp 153-163 (2018)
Parkinson's disease (PD) is a progressive motor neurodegenerative disorder, characterized by a selective loss of dopaminergic neurons in the substantia nigra. The complexity of disease etiology includes both genetic and environmental factors. No effe
Externí odkaz:
https://doaj.org/article/258fc95405b143d0a47d4812b090f97a
Publikováno v:
PLoS ONE, Vol 9, Iss 5, p e97758 (2014)
Parkinson's disease (PD) is the most common motor neurodegenerative disorder. Olfactory dysfunction is a prevalent feature of PD. It often precedes motor symptoms by several years and is used in assisting PD diagnosis. However, the cellular and molec
Externí odkaz:
https://doaj.org/article/85237c0d0b3c4933b6d1e494d34969ca
Publikováno v:
Frontiers in Neural Circuits, Vol 3 (2010)
The last decade has witnessed the identification of single-gene defects associated with an impressive number of mental retardation syndromes. Fragile X syndrome, the most common cause of mental retardation for instance, results from disruption of the
Externí odkaz:
https://doaj.org/article/dd384c2ec31147debc36b94f17c1ac16
Autor:
Gengxin Chen, Wanhe Li, Qing-Shuo Zhang, Michael Regulski, Nishi Sinha, Jody Barditch, Tim Tully, Adrian R Krainer, Michael Q Zhang, Josh Dubnau
Publikováno v:
PLoS Computational Biology, Vol 4, Iss 2, p e1000026 (2008)
Drosophila Pumilio (Pum) protein is a translational regulator involved in embryonic patterning and germline development. Recent findings demonstrate that Pum also plays an important role in the nervous system, both at the neuromuscular junction (NMJ)
Externí odkaz:
https://doaj.org/article/9f2e4416206b43d68529a5b18dc65192
Autor:
Shouzhen Xia, Tim Tully
Publikováno v:
PLoS Biology, Vol 5, Iss 10, p e264 (2007)
Molecular and cellular studies have begun to unravel a neurobiological basis of olfactory processing, which appears conserved among vertebrate and invertebrate species. Studies have shown clearly that experience-dependent coding of odor identity occu
Externí odkaz:
https://doaj.org/article/3b9ea36a718743cc9a3c1005c05d6dc7
Autor:
Tim Tully
Publikováno v:
The Serials Librarian. 81:282-294
Autor:
Hsuan-Wen Lin, Chun-Chao Chen, Ruei-Yu Jhang, Linyi Chen, J. Steven de Belle, Tim Tully, Ann-Shyn Chiang
Publikováno v:
Proceedings of the National Academy of Sciences. 119
Learned experiences are not necessarily consolidated into long-term memory (LTM) unless they are periodic and meaningful. LTM depends on de novo protein synthesis mediated by cyclic AMP response element-binding protein (CREB) activity. In Drosophila
Publikováno v:
Proceedings of the National Academy of Sciences. 118
Episodic events are frequently consolidated into labile memory but are not necessarily transferred to persistent long-term memory (LTM). Regulatory mechanisms leading to LTM formation are poorly understood, however, especially at the resolution of id