Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Tim Seedorf"'
Autor:
Moritz Stappert, Daniel Kohnhäuser, Tim Seedorf, Janetta Coetzee, Katharina Rox, Hazel L. S. Fuchs, Katarina Cirnski, Christian Leitner, Jennifer Herrmann, Andreas Kirschning, Rolf Müller, Mark Brönstrup
Publikováno v:
Communications Chemistry, Vol 7, Iss 1, Pp 1-15 (2024)
Abstract Novel scaffolds for broad-spectrum antibiotics are rare and in strong demand because of the increase in antimicrobial resistance. The cystobactamids, discovered from myxobacterial sources, have a unique hexapeptidic scaffold with five arylam
Externí odkaz:
https://doaj.org/article/b595c14c19e3465bb481bd5a0c131d1a
Autor:
Timo Risch, Dominik Kolling, Dietrich Mostert, Tim Seedorf, Dominik Heimann, Daniel Kohnhäuser, Felix Deschner, Franziska Fries, Danny Solga, Jil-Sophie Hilgers, Jan Dastbaz, Stefano Mancini, Anna K. H. Hirsch, Mark Brönstrup, Andreas Kirschning, Stephan A. Sieber, Jennifer Herrmann, Rolf Müller
Publikováno v:
npj Antimicrobials and Resistance, Vol 2, Iss 1, Pp 1-12 (2024)
Abstract Antimicrobial resistance is one of the major health threats of the modern world. Thus, new structural classes of antimicrobial compounds are needed in order to overcome existing resistance. Cystobactamids represent one such new compound clas
Externí odkaz:
https://doaj.org/article/d82bddf7ab0144049f713a0e4128ea79
Autor:
Timm O. Koller, Ullrich Scheid, Teresa Kösel, Jennifer Herrmann, Daniel Krug, Helena I. M. Boshoff, Bertrand Beckert, Joanna C. Evans, Jan Schlemmer, Becky Sloan, Danielle M. Weiner, Laura E. Via, Atica Moosa, Thomas R. Ioerger, Michael Graf, Boris Zinshteyn, Maha Abdelshahid, Fabian Nguyen, Stefan Arenz, Franziska Gille, Maik Siebke, Tim Seedorf, Oliver Plettenburg, Rachel Green, Anna-Luisa Warnke, Joachim Ullrich, Ralf Warrass, Clifton E. Barry, Digby F. Warner, Valerie Mizrahi, Andreas Kirschning, Daniel N. Wilson, Rolf Müller
Publikováno v:
Journal of the American Chemical Society.
Resistance of bacterial pathogens against antibiotics is declared by WHO as a major global health threat. As novel antibacterial agents are urgently needed, we re-assessed the broad-spectrum myxobacterial antibiotic myxovalargin and found it to be ex
Autor:
Timm O. Koller, Ullrich Scheid, Teresa Kösel, Jennifer Herrmann, Daniel Krug, Helena I. Boshoff, Bertrand Beckert, Joanna C. Evans, Jan Schlemmer, Becky Sloan, Danielle M. Weiner, Laura E. Via, Atica Moosa, Thomas R. Ioerger, Franziska Gille, Maik Siebke, Tim Seedorf, Oliver Plettenburg, Anna-Luisa Warnke, Joachim Ullrich, Ralf Warrass, Clifton E. Barry, Digby F. Warner, Valerie Mizrahi, Andreas Kirschning, Daniel N. Wilson, Rolf Müller
Resistance of bacterial pathogens against antibiotics is declared by WHO as a major global health threat. As novel antibacterial agents are urgently needed, we re-assessed the broad-spectrum myxobacterial antibiotic myxovalargin and found it to be ex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c4f6c283c2b8195cb0e7617a3d4e5c55
https://doi.org/10.26434/chemrxiv-2022-vr3hn
https://doi.org/10.26434/chemrxiv-2022-vr3hn
Publikováno v:
Chemistry – A European Journal. 27
Publikováno v:
Chemistry (Weinheim an Der Bergstrasse, Germany)
The term “privileged structure” refers to a single molecular substructure or scaffold that can serve as a starting point for high‐affinity ligands for more than one receptor type. In this report, a hitherto overlooked group of privileged substr