The effects of acute exercise and inflammation on immune function in early-stage prostate cancer

Autor: Tim Schauer, Sissal Sigmundsdóttir Djurhuus, Casper Simonsen, Klaus Brasso, Jesper Frank Christensen

Publikováno v: Brain, Behavior, & Immunity - Health, Vol 25, Iss , Pp 100508- (2022)

Background: The immune system plays a vital role in cancer development and progression. Strategies mobilizing cytotoxic cells of the immune system to combat immunosuppression in cancer may help to improve the treatment response of patients. To this e

Externí odkaz: https://doaj.org/article/cae376bcbc1f454caffba95e6b229f1a

Pre-treatment levels of inflammatory markers and chemotherapy completion rates in patients with early-stage breast cancer

Autor: Tim Schauer, Anna Henriksson, Emelie Strandberg, Henrik Lindman, Sveinung Berntsen, Ingrid Demmelmaier, Truls Raastad, Karin Nordin, Jesper F. Christensen

Publikováno v: International Journal of Clinical Oncology. 28:89-98

Chemotherapy efficacy is largely dependent on treatment adherence, defined by the relative dose intensity (RDI). Identification of new modifiable risk factors associated with low RDI might improve chemotherapy delivery. Here, we evaluated the associa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71762a164932d3938e84d72f1aea1626
https://doi.org/10.1007/s10147-022-02255-0

A randomized double-blind single center study of testosterone replacement therapy or placebo in testicular cancer survivors with mild Leydig cell insufficiency (Einstein-intervention)

Autor: Michael Kreiberg, Niels Jørgensen, Anders Juul, Jakob Lauritsen, Peter Oturai, Jørn Wulff Helge, Jesper Frank Christensen, Lise Aksglaede, Tim Schauer, Thomas Wagner, Josephine Rosenvilde, Emma Grunwald, Christian Dehlendorff, Gedske Daugaard, Mikkel Bandak

Publikováno v: Kreiberg, M, Jørgensen, N, Juul, A, Lauritsen, J, Oturai, P, Helge, J W, Christensen, J F, Aksglaede, L, Schauer, T, Wagner, T, Rosenvilde, J, Grunwald, E, Dehlendorff, C, Daugaard, G & Bandak, M 2022, ' A randomized double-blind single center study of testosterone replacement therapy or placebo in testicular cancer survivors with mild Leydig cell insufficiency (Einstein-intervention) ', Clinical Genitourinary Cancer, vol. 20, no. 5, pp. 404-414 . https://doi.org/10.1016/j.clgc.2022.04.017

Introduction: Elevated luteinizing hormone (LH) in combination with low-normal testosterone (mild Leydig cell insufficiency) is common in testicular cancer (TC) survivors and is associated with impaired insulin sensitivity and metabolic syndrome. The

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38817562be1f58a12076a17e10a43199
https://curis.ku.dk/portal/da/publications/a-randomized-doubleblind-single-center-study-of-testosterone-replacement-therapy-or-placebo-in-testicular-cancer-survivors-with-mild-leydig-cell-insufficiency-einsteinintervention(2c8e012b-80bc-49b2-9cad-b40bbbb9a5ef).html

Human immune cell mobilization during exercise: effect of IL-6 receptor blockade

Autor: Marie Lund Bay, Regitse Højgaard Christensen, Rikke Krogh-Madsen, Tim Schauer, Sarah E Heywood, Peter Østrup Jensen, Grit Elster Legård, Louise Lang Lehrskov, Anne-Sophie Wedell-Neergaard, Helga Ellingsgaard

Publikováno v: Experimental physiologyREFERENCES. 105(12)

New findings What is the central question of this study? Does blockade of the IL-6 receptor by tocilizumab inhibit immune cell mobilization to the blood stream in humans during an acute bout of exercise? What is the main finding and its importance? B

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ecb22a997cdeb593de4a76063fe1182c
https://pubmed.ncbi.nlm.nih.gov/33006190

Interval Walking Improves Glycemic Control and Body Composition After Cancer Treatment:A Randomized Controlled Trial

Autor: Anders Tolver, Jesper Christensen, Sissal S. Djurhuus, Cecilie K. Olsen, Kirsten Vistisen, Pernille Hojman, Casper Simonsen, Helga Ellingsgaard, Anna Sundberg, Anette B. Nielsen, Bente Klarlund Pedersen, Peter-Martin Krarup, Kell Østerlind, Sarah Thorsen-Streit, Jens Osterkamp, Camilla Stedstrup Mosgaard, Tim Schauer

Publikováno v: Christensen, J F, Sundberg, A, Osterkamp, J, Thorsen-Streit, S, Nielsen, A B, Olsen, C K, Djurhuus, S S, Simonsen, C, Schauer, T, Ellingsgaard, H, Østerlind, K, Krarup, P M, Mosgaard, C, Vistisen, K, Tolver, A, Pedersen, B K & Hojman, P 2019, ' Interval Walking Improves Glycemic Control and Body Composition After Cancer Treatment : A Randomized Controlled Trial ', The Journal of clinical endocrinology and metabolism, vol. 104, no. 9, pp. 3701-3712 . https://doi.org/10.1210/jc.2019-00590

Context Patients with colorectal cancer have increased risk of metabolic diseases including diabetes. Exercise training may counteract metabolic dysregulation, but the impact of exercise training on glycemic control, including postprandial glycemia,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ffc3c5df126c23eea028ad895a53a99
https://curis.ku.dk/portal/da/publications/interval-walking-improves-glycemic-control-and-body-composition-after-cancer-treatment(ded1abe7-e79e-408b-b99f-e206acc39823).html