Zobrazeno 1 - 10
of 152
pro vyhledávání: '"Tim S Bugni"'
Antifungal compounds from Streptomyces associated with attine ants also inhibit Leishmania donovani.
Autor:
Humberto E Ortega, Leonardo L G Ferreira, Weilan G P Melo, Ana Ligia L Oliveira, René F Ramos Alvarenga, Norberto P Lopes, Tim S Bugni, Adriano D Andricopulo, Mônica T Pupo
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 13, Iss 8, p e0007643 (2019)
Bacterial strains isolated from attine ants showed activity against the insect specialized fungal pathogen Escovopsis and also against the human protozoan parasite Leishmania donovani. The bioassay guided fractionation of extracts from cultures of St
Externí odkaz:
https://doaj.org/article/bb8c1e768bed4db6bba3428e89f4f710
Autor:
Gregory A Ellis, Chris S Thomas, Shaurya Chanana, Navid Adnani, Emily Szachowicz, Doug R Braun, Mary Kay Harper, Thomas P Wyche, Tim S Bugni
Publikováno v:
PLoS ONE, Vol 12, Iss 7, p e0176968 (2017)
Bacterial communities associated with marine invertebrates such as sponges and ascidians have demonstrated potential as sources of bio-medically relevant small molecules. Metagenomic analysis has shown that many of these invertebrates harbor populati
Externí odkaz:
https://doaj.org/article/871d33758d394894b03b0345c2ea0554
Autor:
Jason C Kwan, Ma Diarey B Tianero, Mohamed S Donia, Thomas P Wyche, Tim S Bugni, Eric W Schmidt
Publikováno v:
PLoS ONE, Vol 9, Iss 5, p e95850 (2014)
Natural products (secondary metabolites) found in marine invertebrates are often thought to be produced by resident symbiotic bacteria, and these products appear to play a major role in the symbiotic interaction of bacteria and their hosts. In these
Externí odkaz:
https://doaj.org/article/fd3a175f9c684898b06e0a9ed1adbc00
Autor:
Qihao Wu, Bailey A. Bell, Jia-Xuan Yan, Marc G. Chevrette, Nathan J. Brittin, Yanlong Zhu, Shaurya Chanana, Mitasree Maity, Doug R. Braun, Amelia M. Wheaton, Ilia A. Guzei, Ying Ge, Scott R. Rajski, Michael G. Thomas, Tim S. Bugni
Publikováno v:
Journal of the American Chemical Society. 145:58-69
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bb66b0561e4ca0a67d5f0d392c8f53a8
https://doi.org/10.1021/jacs.2c06410
https://doi.org/10.1021/jacs.2c06410
Autor:
Fan Zhang, René F. Ramos Alvarenga, Kurt Throckmorton, Shaurya Chanana, Doug R. Braun, Jen Fossen, Miao Zhao, Sue McCrone, Mary Kay Harper, Scott R. Rajski, Warren E. Rose, David R. Andes, Michael G. Thomas, Tim S. Bugni
Publikováno v:
Organic Letters. 24:3998-4002
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9f5f48ae113e81ba77f48fde277da3bf
https://doi.org/10.1021/acs.orglett.2c01408
https://doi.org/10.1021/acs.orglett.2c01408
Autor:
Kirsten Gotting, Daniel S. May, Jeffrey Sosa-Calvo, Lily Khadempour, Charlotte B. Francoeur, Aileen Berasategui, Margaret W. Thairu, Shelby Sandstrom, Caitlin M. Carlson, Marc G. Chevrette, Mônica T. Pupo, Tim S. Bugni, Ted R. Schultz, J. Spencer Johnston, Nicole M. Gerardo, Cameron R. Currie
Publikováno v:
Daniel Steven May
Fungi shape the diversity of life. Characterizing the evolution of fungi is critical to understanding symbiotic associations across kingdoms. In this study, we investigate the genomic and metabolomic diversity of the genus Escovopsis , a specialized
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::117d31f77e8e60b89f8bb73742c167e6
https://doi.org/10.1073/pnas.2213096119
https://doi.org/10.1073/pnas.2213096119
Autor:
Vladimir Vinnik, Kurt Throckmorton, Taylor B. Cook, Fan Zhang, Hyunjun Park, Michael G. Thomas, Brian F. Pfleger, Tim S. Bugni
Publikováno v:
ACS Chem Biol
Siderophores are iron-chelating molecules produced by microorganisms and plants to acquire exogenous iron. Siderophore biosynthetic enzymology often produces elaborate and unique molecular through unusual reactions to enable specific recognition by t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46479756bb820192b87ff2dcb3504136
https://doi.org/10.1021/acschembio.0c00809
https://doi.org/10.1021/acschembio.0c00809
Autor:
Marc G. Chevrette, Cameron R. Currie, Qihao Wu, Doug R. Braun, Tim S. Bugni, Mitasree Maity, Scott R. Rajski, Michael G. Thomas, Kurt Throckmorton
Publikováno v:
Journal of Natural Products. 84:136-141
Chemical investigation of a marine sponge-associated Bacillus sp. led to the discovery of bacillibactins E and F (1 and 2). Despite containing the well-established cyclic triester core of iron-binding natural products such as enterobactin, bacillibac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::efb7d52f1dae6eaa24350b5a51b8468b
https://doi.org/10.1021/acs.jnatprod.0c01170
https://doi.org/10.1021/acs.jnatprod.0c01170
Autor:
Jack F. V. Hunt, Meng Li, Ryan Risgaard, Gene E. Ananiev, Scott Wildman, Fan Zhang, Tim S. Bugni, Xinyu Zhao, Anita Bhattacharyya
Publikováno v:
Cells; Volume 11; Issue 1; Pages: 69
Cells, Vol 11, Iss 69, p 69 (2022)
Cells
Cells, Vol 11, Iss 69, p 69 (2022)
Cells
Fragile X syndrome (FXS) is the most common inherited cause of autism and intellectual disability. The majority of FXS cases are caused by transcriptional repression of the FMR1 gene due to epigenetic changes that are not recapitulated in current ani
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::091f3a2a608da87b0591f792e1ef71a1
Autor:
Amber Lasek, Jun Wan, Kayla Correia-Staudt, Tim S. Bugni, Kari B. Wisinski, Amber S. Zhou, Stephanie M. McGregor, Amy M. Fowler, Mark E. Burkard, Jonathan Fitzgerald, John B. Tucker, Karla Esbona, Lauren M. Zasadil, Christina M. Scribano, Amye J. Tevaarwerk, Ryan Molini, Beth A. Weaver, Ruth O'Regan, Angela M. Lager, Jennifer Laffin, Rick Chappell
Publikováno v:
Sci Transl Med
Paclitaxel (Taxol) is a cornerstone of cancer treatment. However, its mechanism of cytotoxicity is incompletely understood and not all patients benefit from treatment. We show that patients with breast cancer did not accumulate sufficient intratumora
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c001273086d6d430d83a6c11b9ba2676
https://doi.org/10.1126/scitranslmed.abd4811
https://doi.org/10.1126/scitranslmed.abd4811