Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Tim Rehkämper"'
Autor:
Gero Knittel, Tim Rehkämper, Darya Korovkina, Paul Liedgens, Christian Fritz, Alessandro Torgovnick, Yussor Al-Baldawi, Mona Al-Maarri, Yupeng Cun, Oleg Fedorchenko, Arina Riabinska, Filippo Beleggia, Phuong-Hien Nguyen, F. Thomas Wunderlich, Monika Ortmann, Manuel Montesinos-Rongen, Eugen Tausch, Stephan Stilgenbauer, Lukas P. Frenzel, Marco Herling, Carmen Herling, Jasmin Bahlo, Michael Hallek, Martin Peifer, Reinhard Buettner, Thorsten Persigehl, H. Christian Reinhardt
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-13 (2017)
ATM and TP53 mutations are associated with poor prognosis in chronic lymphocytic leukaemia (CLL). Here the authors generate mouse models of Tp53- and Atm-defective CLL mimicking the high-risk form of human disease and show that Atm-deficient CLL is s
Externí odkaz:
https://doaj.org/article/93c8b6674f2b4c01a38589c9951b35af
Autor:
Gero Knittel, Hans Christian Reinhardt, Clemens A. Schmitt, Martin Peifer, Thorsten Persigehl, Anthony Letai, Arndt Borkhardt, Hamid Kashkar, Reinhard Büttner, Philipp Lohneis, Anna Brunn, Manuel Montesinos-Rongen, Sandrine Sander, Ari M. Melnick, Wendy Béguelin, Laura Pasqualucci, Lukas P. Frenzel, Andreas R. Klatt, Janine Altmüller, Martina Deckert, Marcus Krüger, Janica Wiederstein, Arina Riabinska, Maurice Reimann, Jeremy A. Ryan, Alexandra da Palma Guerreiro, Julia Hauer, Heinz Ahlert, Benedikt W. Pelzer, Ilmars Kisis, Moritz Kochanek, Sanil Bhatia, Sebastian Klein, Alessandra Holzem, Pauline Pfeiffer, Pascal Nieper, Tim Rehkämper, Ruth Flümann
Pharmacological Screen IC50 values
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b24c0c678d7d5feb1dbbae1529f6df7
https://doi.org/10.1158/2643-3230.22542673
https://doi.org/10.1158/2643-3230.22542673
Autor:
Gero Knittel, Hans Christian Reinhardt, Clemens A. Schmitt, Martin Peifer, Thorsten Persigehl, Anthony Letai, Arndt Borkhardt, Hamid Kashkar, Reinhard Büttner, Philipp Lohneis, Anna Brunn, Manuel Montesinos-Rongen, Sandrine Sander, Ari M. Melnick, Wendy Béguelin, Laura Pasqualucci, Lukas P. Frenzel, Andreas R. Klatt, Janine Altmüller, Martina Deckert, Marcus Krüger, Janica Wiederstein, Arina Riabinska, Maurice Reimann, Jeremy A. Ryan, Alexandra da Palma Guerreiro, Julia Hauer, Heinz Ahlert, Benedikt W. Pelzer, Ilmars Kisis, Moritz Kochanek, Sanil Bhatia, Sebastian Klein, Alessandra Holzem, Pauline Pfeiffer, Pascal Nieper, Tim Rehkämper, Ruth Flümann
Based on gene expression profiles, diffuse large B-cell lymphoma (DLBCL) is subdivided into germinal center B-cell–like (GCB) and activated B-cell–like (ABC) DLBCL. Two of the most common genomic aberrations in ABC-DLBCL are mutations in MYD88 as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1be2bb69b8adfd9f6af9c3c822eed536
https://doi.org/10.1158/2643-3230.c.6550018
https://doi.org/10.1158/2643-3230.c.6550018
Autor:
Gero Knittel, Hans Christian Reinhardt, Clemens A. Schmitt, Martin Peifer, Thorsten Persigehl, Anthony Letai, Arndt Borkhardt, Hamid Kashkar, Reinhard Büttner, Philipp Lohneis, Anna Brunn, Manuel Montesinos-Rongen, Sandrine Sander, Ari M. Melnick, Wendy Béguelin, Laura Pasqualucci, Lukas P. Frenzel, Andreas R. Klatt, Janine Altmüller, Martina Deckert, Marcus Krüger, Janica Wiederstein, Arina Riabinska, Maurice Reimann, Jeremy A. Ryan, Alexandra da Palma Guerreiro, Julia Hauer, Heinz Ahlert, Benedikt W. Pelzer, Ilmars Kisis, Moritz Kochanek, Sanil Bhatia, Sebastian Klein, Alessandra Holzem, Pauline Pfeiffer, Pascal Nieper, Tim Rehkämper, Ruth Flümann
Figures S1 - S8
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07095ca1356e2aa915992e51cd1bcf4a
https://doi.org/10.1158/2643-3230.22542679.v1
https://doi.org/10.1158/2643-3230.22542679.v1
Autor:
Ari Melnick, Sanil Bhatia, Janine Altmüller, Arina Riabinska, Tim Rehkämper, Julia Hauer, Andreas R. Klatt, Sebastian Klein, Gero Knittel, Marcus Krüger, Ilmars Kisis, Pauline Pfeiffer, Anthony Letai, Arndt Borkhardt, Wendy Béguelin, Clemens A. Schmitt, Ruth Flümann, Laura Pasqualucci, Hans Christian Reinhardt, Pascal Nieper, Janica L Wiederstein, Sandrine Sander, Alessandra Holzem, Alexandra da Palma Guerreiro, Anna Brunn, Philipp Lohneis, Reinhard Büttner, Maurice Reimann, Martina Deckert, Benedikt W. Pelzer, Hamid Kashkar, Martin Peifer, Manuel Montesinos-Rongen, Heinz Ahlert, Lukas P. Frenzel, Thorsten Persigehl, Moritz Kochanek, Jeremy Ryan
Publikováno v:
Blood Cancer Discov
Based on gene expression profiles, diffuse large B-cell lymphoma (DLBCL) is subdivided into germinal center B-cell–like (GCB) and activated B-cell–like (ABC) DLBCL. Two of the most common genomic aberrations in ABC-DLBCL are mutations in MYD88 as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c55b000b92c1e2206c27474cd8da2c79
https://doi.org/10.1158/2643-3230.bcd-19-0059
https://doi.org/10.1158/2643-3230.bcd-19-0059
Autor:
Reinhard Büttner, Maike Wittersheim, Sarah Hermann, Anna Schmitt, Filippo Beleggia, Roman K. Thomas, Jean Philip Weber, Vonn Walter, Julie George, Thorsten Persigehl, Fabian Doerr, H. Christian Reinhardt, Tim Rehkämper
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-16 (2017)
Scientific Reports
Scientific Reports
Small cell lung cancer (SCLC) is a difficult to treat subtype of lung cancer. One of the hallmarks of SCLC is its almost uniform chemotherapy sensitivity. However, chemotherapy response is typically transient and patients frequently succumb to SCLC w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9ad0d9ed388dd9d99340020975dd1d8
http://link.springer.com/article/10.1038/s41598-017-15840-5
http://link.springer.com/article/10.1038/s41598-017-15840-5
Autor:
R. Büttner, Filippo Beleggia, RK Thomas, Hans Christian Reinhardt, Julie George, T Wahlers, F Dörr, K Hekmat, T. Persigehl, Tim Rehkämper, Anna Schmitt
Publikováno v:
Zentralblatt für Chirurgie - Zeitschrift für Allgemeine, Viszeral-, Thorax- und Gefäßchirurgie.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::861f4ff983e8a8050bbc06a2f324618d
https://doi.org/10.1055/s-0038-1668382
https://doi.org/10.1055/s-0038-1668382
Autor:
Pascal Nieper, Gero Knittel, Ruth Flümann, Anna Schmitt, Tim Rehkämper, Hans Christian Reinhardt
Publikováno v:
Current opinion in hematology. 25(4)
Recent lymphoma genome sequencing projects have shed light on the genomic landscape of indolent and aggressive lymphomas, as well as some of the molecular mechanisms underlying recurrent mutations and translocations in these entities. Here, we review
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0c065be5fe54bcbbefce97b62ac9352
https://pubmed.ncbi.nlm.nih.gov/29702521
https://pubmed.ncbi.nlm.nih.gov/29702521
Autor:
Alessandro Torgovnick, Stephan Stilgenbauer, Arina Riabinska, Yupeng Cun, Filippo Beleggia, Manuel Montesinos-Rongen, Eugen Tausch, Marco Herling, Carmen D. Herling, Yussor Al-Baldawi, Martin Peifer, Gero Knittel, Christian Fritz, Reinhard Buettner, Paul Liedgens, Darya Korovkina, Phuong-Hien Nguyen, Mona Al-Maarri, Oleg Fedorchenko, Michael Hallek, F. Thomas Wunderlich, Monika Ortmann, Jasmin Bahlo, Lukas P. Frenzel, Thorsten Persigehl, H. Christian Reinhardt, Tim Rehkämper
Publikováno v:
Nature Communications
Nature Communications, Vol 8, Iss 1, Pp 1-13 (2017)
Nature Communications, Vol 8, Iss 1, Pp 1-13 (2017)
Chronic lymphocytic leukemia (CLL) remains an incurable disease. Two recurrent cytogenetic aberrations, namely del(17p), affecting TP53, and del(11q), affecting ATM, are associated with resistance against genotoxic chemotherapy (del17p) and poor outc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99ed3d22fa864e042dea2936765a7480
https://doi.org/10.1038/s41467-017-00210-6
https://doi.org/10.1038/s41467-017-00210-6
Autor:
R. Büttner, H. Kashkar, A. Holzem, P. Nieper, C. Reinhardt, R. Fluemann, G. Knittel, Tim Rehkämper, T. Persigehl, P. Pfeiffer, M. Peifer
Publikováno v:
HemaSphere. 3:207
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::561e40d468df53bf220721b08c5e38e6
https://doi.org/10.1097/01.hs9.0000560132.56443.09
https://doi.org/10.1097/01.hs9.0000560132.56443.09