Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Tim Raemaekers"'
Autor:
Veerle Baert, H. Joseph Yost, Nathalie Jurisch-Yaksi, Przemko Tylzanowski, Tim Raemaekers, Applonia Josephine Rose, Guy Froyen, Wendy Vermeire, Cammon B. Arrington, Huiqi Lu, Roel Vandepoel, Emre Yaksi, Daphne Verleyen, Wim Annaert, Pieter Baatsen, Sebastian Munck, Thomy de Ravel, Suzie J. Scales
Publikováno v:
The Journal of Cell Biology
Rer1p is an ER/cis-Golgi membrane protein that maintains ciliary length and function by reducing γ-secretase complex assembly and activity (thereby balancing Notch signaling) and increasing Foxj1a expression.
Cilia project from the surface of m
Cilia project from the surface of m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0670771d5653c4e13cbdb72f0604ace
http://europepmc.org/articles/PMC3601348
http://europepmc.org/articles/PMC3601348
Autor:
Veerle Baert, Christine Michiels, Ragna Sannerud, Aleksandar Peric, Tim Raemaekers, Ilse Declerck, Wim Annaert, Pieter Baatsen
Publikováno v:
The EMBO Journal. 31:3252-3269
Dendritic filopodia are dynamic structures thought to be the precursors of spines during synapse development. Morphological maturation to spines is associated with the stabilization and strengthening of synapses, and can be altered in various neurolo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6c3725321943b0346f06bf332ee8583d
https://doi.org/10.1038/emboj.2012.182
https://doi.org/10.1038/emboj.2012.182
Autor:
Sarah Denayer, Peter Carmeliet, Tim Raemaekers, Mieke Dewerchin, Sophie Torrekens, Geert Carmeliet, Karen Moermans, An Vanden Bosch, Nico Smets
Publikováno v:
Journal of Cell Science. 123:3244-3255
Mitotic spindle assembly is mediated by two processes: a centrosomal and a chromosomal pathway. RanGTP regulates the latter process by releasing microtubule-associated proteins from inhibitory complexes. NuSAP, a microtubule- and DNA-binding protein,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::898e34b7687e47aeccae8d74f17a0756
https://doi.org/10.1242/jcs.063875
https://doi.org/10.1242/jcs.063875
Autor:
Amantha Thathiah, An Snellinx, Karina Reiss, Elke Maes, Bart De Strooper, Paul Saftig, Ellen Jorissen, Uwe Konietzko, Lutgarde Serneels, Tim Raemaekers, Thomas Tousseyn, Omar Nyabi, Wim Annaert, Dieter Hartmann
Publikováno v:
Journal of Biological Chemistry. 284:11738-11747
ADAM10 is involved in the proteolytic processing and shedding of proteins such as the amyloid precursor protein (APP), cadherins, and the Notch receptors, thereby initiating the regulated intramembrane proteolysis (RIP) of these proteins. Here, we de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ebc6241ab5ad2a3a53a504b1bdb70164
https://doi.org/10.1074/jbc.m805894200
https://doi.org/10.1074/jbc.m805894200
Autor:
Carmen Bartic, Yves Engelborghs, Wim Annaert, Bart Van Meerbergen, Micha E. Spira, Kurt Winters, Tim Raemaekers, Dries Braeken, Gustaaf Borghs
Publikováno v:
Journal of Experimental Nanoscience. 2:101-114
Efficient integration of neuronal cells and electronic devices could result in hybrid bi-directional communication systems that would enable us to interact at fundamental levels with biological structures and gain insight in the mechanisms governing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2fdbd4e3173335b007ac874fd8230198
https://doi.org/10.1080/17458080600900347
https://doi.org/10.1080/17458080600900347
Publikováno v:
Current Biology. 17:230-236
Summary The spindle apparatus is a microtubule (MT)-based machinery that attaches to and segregates the chromosomes during mitosis and meiosis. Self-organization of the spindle around chromatin involves the assembly of MTs, their attachment to the ch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d25eefa71b27cb8bc6e0df49979fcace
https://doi.org/10.1016/j.cub.2006.11.050
https://doi.org/10.1016/j.cub.2006.11.050
Autor:
Wim Annaert, Philippa B. Mills, Monty Krieger, Eliza Vasile, Bryan Winchester, François Foulquier, Tim Raemaekers, Gert Matthijs, Dulce Quelhas, Jacques Jaeken, Nico Callewaert, Els Schollen
Publikováno v:
Proceedings of the National Academy of Sciences. 103:3764-3769
The conserved oligomeric Golgi (COG) complex is a heterooctameric complex that regulates intraGolgi trafficking and the integrity of the Golgi compartment in eukaryotic cells. Here, we describe a patient with a mild form of congenital disorder of gly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c23b2a42c5230a58082a0de352a77c10
https://doi.org/10.1073/pnas.0507685103
https://doi.org/10.1073/pnas.0507685103
Autor:
Katrijn Coen, Sebastian Munck, Bart De Strooper, Giampietro Schiavo, Lujia Zhou, Guillermo Menendez, Aleksandar Peric, Wim Annaert, Baert Veerle, Tim Raemaekers, Ragna Sannerud, Ilse Declerck
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 108(34)
Amyloid β (Aβ) peptides, the primary constituents of senile plaques and a hallmark in Alzheimer's disease pathology, are generated through the sequential cleavage of amyloid precursor protein (APP) by β-site APP cleaving enzyme 1 (BACE1) and γ-se
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4cfd40e970b98cc2105c5c490d6ca7ff
https://pubmed.ncbi.nlm.nih.gov/21825135
https://pubmed.ncbi.nlm.nih.gov/21825135
Autor:
Matthias Landgraf, Ariane Ramaekers, Andrzej Drozdzecki, Tim Raemaekers, Laura Nicolaï, Alex S. Mauss, Wim W. Annaert, Bassem A. Hassan, Jiekun Yan
In recent years, Drosophila melanogaster has emerged as a powerful model for neuronal circuit development, pathology, and function. A major impediment to these studies has been the lack of a genetically encoded, specific, universal, and phenotypicall
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::882e2b79bf41e8bd04dd696c9f44dfea
https://europepmc.org/articles/PMC2996714/
https://europepmc.org/articles/PMC2996714/
Autor:
Dragana Spasic, Veerle Baert, Katleen Dillen, Wim Annaert, Lutgarde Serneels, Ilse Declerck, Tim Raemaekers, Joachim Füllekrug
Publikováno v:
The Journal of Cell Biology
The gamma-secretase complex, consisting of presenilin, nicastrin, presenilin enhancer-2 (PEN-2), and anterior pharynx defective-1 (APH-1) cleaves type I integral membrane proteins like amyloid precursor protein and Notch in a process of regulated int
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c624afd8c287c1a6f11df4a6491cf792
https://pubmed.ncbi.nlm.nih.gov/17325205
https://pubmed.ncbi.nlm.nih.gov/17325205