Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Tim Peakman"'
Autor:
Aiden Doherty, Dan Jackson, Nils Hammerla, Thomas Plötz, Patrick Olivier, Malcolm H Granat, Tom White, Vincent T van Hees, Michael I Trenell, Christoper G Owen, Stephen J Preece, Rob Gillions, Simon Sheard, Tim Peakman, Soren Brage, Nicholas J Wareham
Publikováno v:
PLoS ONE, Vol 12, Iss 2, p e0169649 (2017)
BACKGROUND:Physical activity has not been objectively measured in prospective cohorts with sufficiently large numbers to reliably detect associations with multiple health outcomes. Technological advances now make this possible. We describe the method
Externí odkaz:
https://doaj.org/article/ccd18cb32c254941b0dca48a1b08c10e
Autor:
Cathie Sudlow, John Gallacher, Naomi Allen, Valerie Beral, Paul Burton, John Danesh, Paul Downey, Paul Elliott, Jane Green, Martin Landray, Bette Liu, Paul Matthews, Giok Ong, Jill Pell, Alan Silman, Alan Young, Tim Sprosen, Tim Peakman, Rory Collins
Publikováno v:
PLoS Medicine, Vol 12, Iss 3, p e1001779 (2015)
Cathie Sudlow and colleagues describe the UK Biobank, a large population-based prospective study, established to allow investigation of the genetic and non-genetic determinants of the diseases of middle and old age.
Externí odkaz:
https://doaj.org/article/c2a625d7ee1c47e2895de5cb79fcf5f2
Autor:
Stephen Kaptoge, Emanuele Di Angelantonio, Carmel Moore, Matthew Walker, Jane Armitage, Willem H Ouwehand, David J Roberts, John Danesh, Simon G Thompson, Jenny Donovan, Ian Ford, Rachel Henry, Beverley J Hunt, Bridget le Huray, Susan Mehenny, Gail Miflin, Jane Green, Mike Stredder, Nicholas A Watkins, Alan McDermott, Clive Ronaldson, Claire Thomson, Zoe Tolkien, Lorna Williamson, David Allan, Jennifer Sambrook, Tracey Hammerton, David Bruce, Fizzah Choudry, Cedric Ghvaert, Kirstie Jonston, Anne Kelly, Andrew King, Alfred Mo, Lizanne Page, Penny Richardson, Peter Senior, Yagnesh Umrania, Henna Wong, Brendan Burchell, John Gallacher, Gavin Murphy, Adrian C Newland, Keith Wheatley, Michael Greaves, Marc Turner, Tahir Aziz, Richard Brain, Christine Davies, Ruth Turner, Paula Wakeman, Alison Dent, Alan Wakeman, Ben Anthony, Desmond Bland, Willem H Parrondo, Helen Vincent, Candy Weatherill, Andrea Forsyth, Carol Butterfield, Tracey Wright, Karen Ellis, Kristie Johnston, Pat Poynton, Carolyn Brooks, Emma Martin, Lara Littler, Lindsay Williamson, Donna Blair, Karen Ackerley, Lynn Woods, Sophie Stanley, Gemma Walsh, Gayle Franklin, Cheryl Howath, Sarah Sharpe, Deborah Smith, Lauren Botham, Caroline Williams, Claire Alexander, Gareth Sowerbutts, Diane Furnival, Michael Thake, Shilpa Patel, Carolyn Roost, Sandra Sowerby, Mary Joy Appleton, Eileen Bays, Geoff Bowyer, Steven Clarkson, Stuart Halson, Kate Holmes, Gareth Humphreys, Lee Parvin-Cooper, Jason Towler, Joanne Addy, Patrica Barrass, Louise Stennett, Susan Burton, Hannah Dingwell, Victoria Clarke, Maria Potton, Thomas Bolton, Michael Daynes, Sarah Spackman, Michael Walker, Abudu Momodu, James Fenton, Adam King, Omer Muhammad, Nicholas Oates, Tim Peakman, Christine Ryan, Kristian Spreckley, Craig Stubbins, Joanna Williams, James Brannan, Cedric Mochon, Samantha Taylor, Kimberly Warren, Jonathan Mant
Publikováno v:
The Lancet. Haematology
Summary Background The INTERVAL trial showed that, over a 2-year period, inter-donation intervals for whole blood donation can be safely reduced to meet blood shortages. We extended the INTERVAL trial for a further 2 years to evaluate the longer-term
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8822578de35e1c32b53e6517fd8d63d
https://www.repository.cam.ac.uk/handle/1810/293604
https://www.repository.cam.ac.uk/handle/1810/293604
Autor:
Emanuele Di Angelantonio, Simon G Thompson, Stephen Kaptoge, Carmel Moore, Matthew Walker, Jane Armitage, Willem H Ouwehand, David J Roberts, John Danesh, Jenny Donovan, Ian Ford, Rachel Henry, Beverley J Hunt, Bridget Le Huray, Susan Mehenny, Gail Miflin, Jane Green, Mike Stredder, Nicholas A Watkins, Alan McDermott, Clive Ronaldson, Claire Thomson, Zoe Tolkien, Lorna Williamson, David Allen, Jennifer Sambrook, Tracey Hammerton, David Bruce, Fizzah Choudry, Cedric Ghevaert, Kirstie Johnston, Anne Kelly, Andrew King, Alfred Mo, Lizanne Page, Penny Richardson, Peter Senior, Yagnesh Umrania, Henna Wong, Gavin Murphy, Adrian C Newland, Keith Wheatley, Michael Greaves, Marc Turner, Tahir Aziz, Richard Brain, Christine Davies, Ruth Turner, Paula Wakeman, Alison Dent, Alan Wakeman, Ben Anthony, Desmond Bland, Will Parrondo, Helen Vincent, Candy Weatherill, Andrea Forsyth, Carol Butterfield, Tracey Wright, Karen Ellis, Pat Poynton, Carolyn Brooks, Emma Martin, Lara Littler, Lindsay Williams, Donna Blair, Karen Ackerley, Lynn Woods, Sophie Stanley, Gemma Walsh, Gayle Franklin, Cheryl Howath, Sarah Sharpe, Deborah Smith, Lauren Botham, Caroline Williams, Claire Alexander, Gareth Sowerbutts, Diane Furnival, Michael Thake, Shilpa Patel, Carolyn Roost, Sandra Sowerby, Mary Joy Appleton, Eileen Bays, Geoff Bowyer, Steven Clarkson, Stuart Halson, Kate Holmes, Gareth Humphries, Lee Parvin-Cooper, Jason Towler, Joanne Addy, Patricia Barrass, Louise Stennett, Susan Burton, Hannah Dingwall, Victoria Clarke, Maria Potton, Thomas Bolton, Michael Daynes, Sarah Spackman, Abudu Momodu, James Fenton, Adam King, Omer Muhammed, Nicholas Oates, Tim Peakman, Christine Ryan, Kristian Spreckley, Craig Stubbins, Joanna Williams, James Brennan, Cedric Mochon, Samantha Taylor, Kimberley Warren, Jonathan Mant
Publikováno v:
Lancet (London, England)
Summary Background Limits on the frequency of whole blood donation exist primarily to safeguard donor health. However, there is substantial variation across blood services in the maximum frequency of donations allowed. We compared standard practice i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ce482ff9edb4af9b37f4a1a81be945a
https://ora.ox.ac.uk/objects/uuid:0ad1a9fe-f44c-4172-8ef2-52dfb55e8ac0
https://ora.ox.ac.uk/objects/uuid:0ad1a9fe-f44c-4172-8ef2-52dfb55e8ac0
Autor:
Nicholas J. Wareham, Aiden R. Doherty, Rob Gillions, Malcolm H. Granat, Dan Jackson, Tim Peakman, Stephen J. Preece, Christoper G. Owen, Michael I. Trenell, Vincent T. van Hees, Nils Y. Hammerla, Thomas E. White, Patrick Olivier, Thomas Plötz, Soren Brage, S.M. Sheard
Publikováno v:
PLoS ONE
PLoS ONE, Vol 12, Iss 2, p e0169649 (2017)
PLoS ONE, Vol 12, Iss 2, p e0169649 (2017)
Background Physical activity has not been objectively measured in prospective cohorts with sufficiently large numbers to reliably detect associations with multiple health outcomes. Technological advances now make this possible. We describe the method
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56c517237c2d01b9a2f9a913915c8741
https://openaccess.sgul.ac.uk/id/eprint/108480/7/journal.pone.0169649.pdf
https://openaccess.sgul.ac.uk/id/eprint/108480/7/journal.pone.0169649.pdf
Publikováno v:
International Journal of Epidemiology
Background: Errors, introduced through poor assessment of physical measurement or because of inconsistent or inappropriate standard operating procedures for collecting, processing, storing or analysing haematological and biochemistry analytes, have a
Autor:
Pamela M. Marcus, Rory Collins, J. Michael Gaziano, John R. McLaughlin, Robert N. Hoover, Francis S. Collins, Nancy L. Pedersen, Tim Sprosen, Teri A. Manolio, Chris Berg, Alpa V. Patel, Catherine A. McCarty, Catherine C. Cowie, Steven Hirschfeld, Tim Peakman, Catherine Schaefer, Brenda K. Weis, Joan Scott, Barnett S. Kramer, Mark Walport, Daniel R. Masys, Wendy Ewart, Kathy L. Hudson
Publikováno v:
American Journal of Epidemiology
Large prospective cohort studies are critical for identifying etiologic factors for disease, but they require substantial long-term research investment. Such studies can be conducted as multisite consortia of academic medical centers, combinations of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09d7b7b167ac74a82b90a0234df7a48a
https://doi.org/10.1093/aje/kwr453
https://doi.org/10.1093/aje/kwr453
Publikováno v:
BMC Genomics
Background UK Biobank is a large prospective cohort study in the UK established by the Medical Research Council (MRC) and the Wellcome Trust to enable approved researchers to investigate the role of genetic factors, environmental exposures and lifest
Autor:
Paul Downey, Tim Peakman
Publikováno v:
International Journal of Epidemiology. 37:i46-i50
BACKGROUND UK Biobank is a prospective study that is collecting biological samples and health and lifestyle data from 500 000 volunteer participants over a 4-year period. These data will be used to facilitate biological and medical research. METHODS
Autor:
Tim Peakman, Naomi E. Allen, Jane Green, Cathie Sudlow, Paul M. Matthews, Martin J Landray, Paul Elliott, Alan Young, Bette Liu, Paul Downey, Jill P. Pell, Rory Collins, John Gallacher, Valerie Beral, Paul Burton, Alan J. Silman, John Danesh, Tim Sprosen, Giok Ong
Publikováno v:
PLoS Medicine, Vol 12, Iss 3, p e1001779 (2015)
PLoS Medicine
Sudlow, C, Gallacher, J, Allen, N, Beral, V, Burton, P, Danesh, J, Downey, P, Elliott, P, Green, J, Landray, M, Liu, B, Matthews, P, Ong, G, Pell, J, Silman, A, Young, A, Sprosen, T, Peakman, T & Collins, R 2015, ' UK biobank: an open access resource for identifying the causes of a wide range of complex diseases of middle and old age ', PLoS Medicine, vol. 12, no. 3, e1001779 . https://doi.org/10.1371/journal.pmed.1001779
PLoS Medicine
Sudlow, C, Gallacher, J, Allen, N, Beral, V, Burton, P, Danesh, J, Downey, P, Elliott, P, Green, J, Landray, M, Liu, B, Matthews, P, Ong, G, Pell, J, Silman, A, Young, A, Sprosen, T, Peakman, T & Collins, R 2015, ' UK biobank: an open access resource for identifying the causes of a wide range of complex diseases of middle and old age ', PLoS Medicine, vol. 12, no. 3, e1001779 . https://doi.org/10.1371/journal.pmed.1001779
The challenge of understanding the determinants of common life-threatening and disabling conditions is substantial. These conditions are typically caused by a combination of lifestyle, environmental, and genomic factors, with individually modest effe