Výsledky vyhledávání - "Tim P. Keith"

Mutations in the human 5-lipoxygenase gene

Autor: Eric S. Silverman, Kwang Ho In, Tim P. Keith, David R. Beier, Koichiro Asano, Andrew R. Fischer, George T. De Sanctis, Kristina Serino, Chandri N. Yandava, Jeffrey M. Drazen

Publikováno v: Clinical Reviews in Allergy & Immunology. 17:59-69

Our data demonstrate the presence of a naturally occurring family of alleles in the core promoter of the 5-LO gene, which is characterized by the deletion or addition of consensus Sp1 (-GGGCGG) and Egr-1 (-GCGGGGGCG-) binding motifs. Each of the vari

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa6148043de6f284d1ff428fbb15817d
https://doi.org/10.1007/bf02737597

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Association of asthma with a functional promoter polymorphism in the IL16 gene

Autor: Kristin M, Burkart, Sheila J, Barton, John W, Holloway, Ian A, Yang, Julie A, Cakebread, William, Cruikshank, Frederic, Little, Xiaoyi, Jin, Lindsay A, Farrer, Joanne B, Clough, Tim P, Keith, Stephen, Holgate, David M, Center, George T, O'Connor

Publikováno v: The Journal of allergy and clinical immunology. 117(1)

Background IL-16, a multifunctional cytokine with increased expression in the airways of asthmatic subjects, inhibits allergic airway inflammation in animal models. A T→C single nucleotide polymorphism (SNP) at the −295 position in the promoter r

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::845344c63b1f4b9c5c0d38db1f066198
https://pubmed.ncbi.nlm.nih.gov/16387589

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