Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Tim P. Hogervorst"'
Autor:
Rui-Jun Eveline Li, Tim P. Hogervorst, Silvia Achilli, Sven C. M. Bruijns, Sander Spiekstra, Corinne Vivès, Michel Thépaut, Dmitri V. Filippov, Gijs A. van der Marel, Sandra J. van Vliet, Franck Fieschi, Jeroen D. C. Codée, Yvette van Kooyk
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
Langerhans cells (LCs) are antigen-presenting cells that reside in the skin. They uniquely express high levels of the C-type lectin receptor Langerin (CD207), which is an attractive target for antigen delivery in immunotherapeutic vaccination strateg
Externí odkaz:
https://doaj.org/article/85f1597e8e6748afb698b1efd024ac0c
Autor:
Rui-Jun Eveline Li, Tim P. Hogervorst, Silvia Achilli, Sven C. Bruijns, Tim Arnoldus, Corinne Vivès, Chung C. Wong, Michel Thépaut, Nico J. Meeuwenoord, Hans van den Elst, Herman S. Overkleeft, Gijs A. van der Marel, Dmitri V. Filippov, Sandra J. van Vliet, Franck Fieschi, Jeroen D. C. Codée, Yvette van Kooyk
Publikováno v:
Frontiers in Chemistry, Vol 7 (2019)
Dendritic cells (DCs) are important initiators of adaptive immunity, and they possess a multitude of Pattern Recognition Receptors (PRR) to generate an adequate T cell mediated immunity against invading pathogens. PRR ligands are frequently conjugate
Externí odkaz:
https://doaj.org/article/7fddd65bb74d4e4eab8466df32613fe6
Autor:
Tim P Hogervorst, Lorenzo Albertazzi, Ward Doelman, Jeroen D. C. Codée, Evangelia Bolli, Roger Riera, Silvia Pujals, Sander I. van Kasteren, Yan Ni
Publikováno v:
Nature Chemical Biology
Nature Chemical Biology, 17, 1281-1288
Nature Chemical Biology, 17(12). Nature Publishing Group
Nature Chemical Biology, 17, 1281-1288
Nature Chemical Biology, 17(12). Nature Publishing Group
Most lectins bind carbohydrate ligands with relatively low affinity, making the identification of optimal ligands challenging. Here we introduce a point accumulation in nanoscale topography (PAINT) super-resolution microscopy method to capture weak g
Autor:
Toroa McGlinn, Gijsbert A. van der Marel, Elena Tondini, Nico J. Meeuwenoord, Ferry Ossendorp, Dmitri V. Filippov, Niels R. M. Reintjens, Jeroen D. C. Codée, Herman S. Overkleeft, Tim P Hogervorst, Christopher A. Vis
Publikováno v:
ChemBioChem, 22(2), 434-440. WILEY-V C H VERLAG GMBH
Chembiochem
ChemBioChem, 22(2), 434-440
ChemBioChem
Chembiochem
ChemBioChem, 22(2), 434-440
ChemBioChem
Mannose‐6‐phosphate (M6P) is recognized by the mannose‐6‐phosphate receptor and plays an important role in the transport of cargo to the endosomes, making it an attractive tool to improve endosomal trafficking of vaccines. We describe herein
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fae0a8e759212651fbd10f130e035f3c
https://doi.org/10.1002/cbic.202000538
https://doi.org/10.1002/cbic.202000538
Autor:
Roger, Riera, Tim P, Hogervorst, Ward, Doelman, Yan, Ni, Silvia, Pujals, Evangelia, Bolli, Jeroen D C, Codée, Sander I, van Kasteren, Lorenzo, Albertazzi
Publikováno v:
Nature chemical biology. 17(12)
Most lectins bind carbohydrate ligands with relatively low affinity, making the identification of optimal ligands challenging. Here we introduce a point accumulation in nanoscale topography (PAINT) super-resolution microscopy method to capture weak g
Autor:
Romà Surís-Valls, Tim P. Hogervorst, Sandra M. C. Schoenmakers, Marco M. R. M. Hendrix, Lech Milroy, Ilja K. Voets
Publikováno v:
Biomacromolecules, 23(2), 520-529. American Chemical Society
Biomacromolecules, 23(2), 520. American Chemical Society : Division of Carbohydrate Chemistry
Biomacromolecules, 23(2), 520. American Chemical Society : Division of Carbohydrate Chemistry
While most native ice-binding proteins are rigid, artificial (macro)molecular ice-binders are usually flexible. Realizing a regular array with precisely positioned ice-binding motifs on synthetic proteins, (macro)molecular ice-binders are thus challe
Autor:
Michel Thépaut, Franck Fieschi, Corinne Vivès, Sandra J. van Vliet, Hans van den Elst, Tim Arnoldus, Sven C. M. Bruijns, Rui Jun Eveline Li, Nico J. Meeuwenoord, Gijs A. van der Marel, Herman S. Overkleeft, Tim P Hogervorst, Dmitri V. Filippov, Jeroen D. C. Codée, Silvia Achilli, Yvette van Kooyk, Chung C. Wong
Publikováno v:
Frontiers in Chemistry, 7:650. Bentham Science Publishers B.V.
Frontiers in Chemistry
Frontiers in Chemistry, Vol 7 (2019)
Frontiers in chemistry, 7, 650
Li, R J E, Hogervorst, T P, Achilli, S, Bruijns, S C, Arnoldus, T, Vivès, C, Wong, C C, Thépaut, M, Meeuwenoord, N J, van den Elst, H, Overkleeft, H S, van der Marel, G A, Filippov, D V, van Vliet, S J, Fieschi, F, Codée, J D C & van Kooyk, Y 2019, ' Systematic Dual Targeting of Dendritic Cell C-Type Lectin Receptor DC-SIGN and TLR7 Using a Trifunctional Mannosylated Antigen ', Frontiers in Chemistry, vol. 7, 650 . https://doi.org/10.3389/fchem.2019.00650
Frontiers in Chemistry, Frontiers Media, 2019, 7, pp.650. ⟨10.3389/fchem.2019.00650⟩
Frontiers in chemistry
Frontiers in Chemistry, 2019, 7, pp.650. ⟨10.3389/fchem.2019.00650⟩
Frontiers in Chemistry
Frontiers in Chemistry, Vol 7 (2019)
Frontiers in chemistry, 7, 650
Li, R J E, Hogervorst, T P, Achilli, S, Bruijns, S C, Arnoldus, T, Vivès, C, Wong, C C, Thépaut, M, Meeuwenoord, N J, van den Elst, H, Overkleeft, H S, van der Marel, G A, Filippov, D V, van Vliet, S J, Fieschi, F, Codée, J D C & van Kooyk, Y 2019, ' Systematic Dual Targeting of Dendritic Cell C-Type Lectin Receptor DC-SIGN and TLR7 Using a Trifunctional Mannosylated Antigen ', Frontiers in Chemistry, vol. 7, 650 . https://doi.org/10.3389/fchem.2019.00650
Frontiers in Chemistry, Frontiers Media, 2019, 7, pp.650. ⟨10.3389/fchem.2019.00650⟩
Frontiers in chemistry
Frontiers in Chemistry, 2019, 7, pp.650. ⟨10.3389/fchem.2019.00650⟩
International audience; Dendritic cells (DCs) are important initiators of adaptive immunity, and they possess a multitude of Pattern Recognition Receptors (PRR) to generate an adequate T cell mediated immunity against invading pathogens. PRR ligands
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e0098e3e9ff9a53aaf120a1be6af189
https://research.vumc.nl/en/publications/72064e25-c174-48a8-a11c-864231636f40
https://research.vumc.nl/en/publications/72064e25-c174-48a8-a11c-864231636f40
Autor:
Tim P Hogervorst, Jeroen D. C. Codée, Xianwen Lou, E. W. Meijer, Gijsbert A. van der Marel, René P. M. Lafleur, Simone I. S. Hendrikse, Lu Su
Publikováno v:
Journal of the American Chemical Society
Journal of the American Chemical Society, 141(35), 13877-13886
Journal of the American Chemical Society, 141(35), 13877-13886. American Chemical Society
Journal of the American Chemical Society, 141(35), 13877-13886
Journal of the American Chemical Society, 141(35), 13877-13886. American Chemical Society
Polysaccharides present in the glycocalyx and extracellular matrix are highly important for a multitude of functions. Oligo- and polysaccharides-based biomaterials are being developed to mimic the glycocalyx, but the spatial functionalization of thes
Autor:
Geoffroy P.P. Gential, Ferry Ossendorp, Tim P Hogervorst, Herman S. Overkleeft, Gijsbert A. van der Marel, Michel J. van de Graaff, Jeroen D. C. Codée, Elena Tondini, Dmitri V. Filippov
Publikováno v:
Bioorganic and Medicinal Chemistry Letters, 29(11), 1340-1344
Bioorganic and Medicinal Chemistry Letters
Bioorganic and Medicinal Chemistry Letters
Covalent linking of immunogenic oligopeptides with synthetic Toll-like receptor ligands is a useful approach to develop self-adjuvanting vaccines. In particular, small-molecule based agonists of Toll-like receptor 7 (TLR7) that are derived from 8-oxo