Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Tim Olsson"'
Publikováno v:
Current Genetics. 26:553-556
The histone-encoding genes in Schizosaccharomyces pombe were physically mapped by hybridisation to filters containing cosmid and P1 genomic libraries. The H2A.2 gene and the H2A.1-H2B.1 gene pair mapped between the ade6 and rikI genes on chromosome I
Publikováno v:
Current genetics. 35(2)
We have investigated the effects of inhibition of histone de-acetylase activity on silencing at the silent mating-type loci in fission yeast. Treatment of exponentially growing cells with the histone deacetylase inhibitor, trichostatin A (TSA), resul
Publikováno v:
Molecular biology of the cell. 9(3)
We have studied telomere length in Schizosaccharomyces pombe strains carrying mutations affecting cell cycle checkpoints, DNA repair, and regulation of the Cdc2 protein kinase. Telomere shortening was found in rad1,rad3, rad17, and rad26mutants. Telo
Publikováno v:
Cell. 91(7)
Histone acetylation may act to mark and maintain transcriptionally active or inactive chromosomal domains through the cell cycle and in different lineages. A novel role for histone acetylation in centromere regulation has been identified. Exposure of
Autor:
Stephen J. Miller, John MacLaughlin, Rolf Ohlsson, Ulf J. Eriksson, Marcel Pilartz, Tharappel C. James, Ragnar Mattsson, Parri Wentzel, Kristian Svensson, Tim Olsson
Publikováno v:
Development (Cambridge, England). 125(1)
Transcriptional silencing can reflect heritable, epigenetic inactivation of genes, either singly or in groups, during the life-time of an organism. This phenomenon is exemplified by parent-of-origin-specific inactivation events (genomic imprinting) f
Publikováno v:
Nucleic acids research. 21(4)
We show that in fission yeast two DNA fragments at the silent P mating type locus provide plasmids with the capability of autonomous replication. Bacterial vectors containing these sequences replicate in a polymeric form in fission yeast very much li
Trans-acting factors and properly positioned DNA elements repress mating-type genes in fission yeast
Publikováno v:
Current genetics. 21(4-5)
Repression of the mating-type P genes at the silent mat2-P locus in fission yeast is dependent on four cis-acting DNA elements, two on each side of the coding sequences. The mechanism by which these elements exert their influence on the mating-type p