Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Tim Miedema"'
Autor:
Felipe Cabral‐Miranda, Giovanni Tamburini, Gabriela Martinez, Alvaro O Ardiles, Danilo B Medinas, Yannis Gerakis, Mei‐Li Diaz Hung, René Vidal, Matias Fuentealba, Tim Miedema, Claudia Duran‐Aniotz, Javier Diaz, Cristobal Ibaceta‐Gonzalez, Carleen M Sabusap, Francisca Bermedo‐Garcia, Paula Mujica, Stuart Adamson, Kaitlyn Vitangcol, Hernan Huerta, Xu Zhang, Tomohiro Nakamura, Sergio Pablo Sardi, Stuart A Lipton, Brian K Kennedy, Juan Pablo Henriquez, J Cesar Cárdenas, Lars Plate, Adrian G Palacios, Claudio Hetz
Publikováno v:
The EMBO Journal. 41
Aging is a major risk factor to develop neurodegenerative diseases and is associated with decreased buffering capacity of the proteostasis network. We investigated the significance of the unfolded protein response (UPR), a major signaling pathway act
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::474993c75fc394a4e5abf662a623e8f9
https://doi.org/10.15252/embj.2022111952
https://doi.org/10.15252/embj.2022111952
Autor:
Thiziri Nait Achour, Nicolas Stankovic-Valentin, Judith Doppel, Carsten Sticht, Frauke Melchior, Lucie M. Wolf, Tim Miedema, Aarushi Vasudeva, Henning Urlaub, Samir Karaca, Sina V. Barysch
Publikováno v:
EMBO Reports
Molecular switches are essential modules in signaling networks and transcriptional reprogramming. Here, we describe a role for small ubiquitin‐related modifier SUMO as a molecular switch in epidermal growth factor receptor (EGFR) signaling. Using q
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2641630292255e0d5281979f96d6f5d
https://hdl.handle.net/21.11116/0000-000A-8392-C21.11116/0000-000A-839C-2
https://hdl.handle.net/21.11116/0000-000A-8392-C21.11116/0000-000A-839C-2
Autor:
Xu Zhang, Cristobal Ibaceta Ibaceta-Gonzalez, Stuart A. Lipton, Stuart S. Adamson, Claudio Hetz, Claudia Duran-Aniotz, Carleen Sabusap, Giovanni Tamburini, Hernan Huerta, Adrian G. Palacios, Kaitlyn Vitangcol, Tomohiro Nakamura, Tim Miedema, Francisca Bermedo, Danilo B. Medinas, S. Pablo Sardi, Felipe Cabral-Miranda, Yannis Gerakis, Alvaro O. Ardiles, Julio Matus, Juan Pablo Henríquez, Gabriela Martínez, Lars Plate, Brian K. Kennedy
Brain ageing is the main risk factor to develop dementia and neurodegenerative diseases, associated with a decay in the buffering capacity of the proteostasis network. We investigated the significance of the unfolded protein response (UPR), a major s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8eaf1474df3730b09b4553264afe5af0
https://doi.org/10.21203/rs.3.rs-83658/v1
https://doi.org/10.21203/rs.3.rs-83658/v1
Autor:
Kaitlyn Vitangcol, Xu Zhang, Giovanni Tamburini, Gabriela Martínez, Yannis Gerakis, Lars Plate, Francisca Bermedo-Garcia, Tomohiro Nakamura, Alvaro Ardilles, Julio Cardenas Cardenas, S. Pablo Sardi, Danilo B. Medinas, Felipe Cabral Miranda, Adrian G. Palacios, Claudia Duran-Aniotz, Juan Pablo Henríquez, Cristobal Ibaceta, Stuart A. Lipton, Carleen Sabusap, Tim Miedema, Stuart S. Adamson, Brian K. Kennedy, Claudio Hetz, Hernan Huerta
Aging is the major risk factor for the development of dementia and neurodegenerative disorders, and the aging brain manifests severe deficits in buffering capacity by the proteostasis network. Accordingly, we investigated the significance of the unfo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b4b13d30da3d9174f42e0ab997d7c97
Autor:
Jens, Meschede, Maria, Šadić, Nikolas, Furthmann, Tim, Miedema, Dominik A, Sehr, A Kathrin, Müller-Rischart, Verian, Bader, Lena A, Berlemann, Anna, Pilsl, Anita, Schlierf, Katalin, Barkovits, Barbara, Kachholz, Katrin, Rittinger, Fumiyo, Ikeda, Katrin, Marcus, Liliana, Schaefer, Jörg, Tatzelt, Konstanze F, Winklhofer
Publikováno v:
Sci Signal
The parkin coregulated gene (PACRG), which encodes a protein of unknown function, shares a bi-directional promoter with parkin (PRKN), which encodes an E3 ubiquitin ligase. Because PRKN is important in mitochondrial quality control and protection aga
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2137f29a64d34864cbaa1fc479e9510d
https://pubmed.ncbi.nlm.nih.gov/32019898
https://pubmed.ncbi.nlm.nih.gov/32019898
Autor:
Katalin Barkovits, Fumiyo Ikeda, Liliana Schaefer, Nikolas Furthmann, Anita Schlierf, Jens Meschede, Tim Miedema, Dominik A. Sehr, Anna Pilsl, Lena A. Berlemann, Jörg Tatzelt, Maria Šadić, Katrin Rittinger, Konstanze F. Winklhofer, Verian Bader, A. Kathrin Müller-Rischart, Barbara Kachholz, Katrin Marcus
Publikováno v:
Science Signaling. 13
The Parkin-coregulated gene (PACRG), which encodes a protein of unknown function, shares a bidirectional promoter with Parkin (PRKN), which encodes an E3 ubiquitin ligase. Because PRKN is important in mitochondrial quality control and protection agai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::13c2d1ffca4c832da65a6cee8b0c3b36
https://doi.org/10.1126/scisignal.aav1256
https://doi.org/10.1126/scisignal.aav1256