Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Tim Marquart"'
Autor:
Rao Kalla, Xiaofen Li, Thao Perry, Mark Micklatcher, Jeff Zablocki, Yuzhi Wu, Tim Marquart, Yuan Li, Elfatih Elzein, Dewan Zeng
Publikováno v:
Bioorganicmedicinal chemistry letters. 17(1)
A series of new selective, high affinity A(1)-AdoR agonists is reported. Compound 23 that incorporated a carboxylic acid functionality in the 4-position of the pyrazole ring displayed K(iL) value of 1 nM for the A(1)-AdoR and5000-fold selectivity ove
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f9c92ff65294ce4103cde14d411ffa1
https://pubmed.ncbi.nlm.nih.gov/17045477
https://pubmed.ncbi.nlm.nih.gov/17045477
Autor:
Tim Marquart, Dewan Zeng, Elfatih Elzein, Suresh S. Kerwar, Nancy Chu, Daniel Soohoo, Prabha Ibrahim, Kevin D. Shenk, Stephanie Meyer, Jeff Zablocki, Kwan Leung, Shirley Wong, Hiba Ahmed
Publikováno v:
Bioorganicmedicinal chemistry letters. 14(4)
We describe the synthesis of novel inhibitors of fatty acid oxidation as potential metabolic modulators for the treatment of stable angina. Replacement of the 2H-benzo[d]1,3-dioxolene ring system in our initial lead 3 with different benzthiazoles, be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0aa93aafef5570a450e7df9908ea66a8
https://pubmed.ncbi.nlm.nih.gov/15013004
https://pubmed.ncbi.nlm.nih.gov/15013004