Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Tim L. Houck"'
Autor:
Adam E. Goetz, Husein Becirovic, Florian Blasberg, Bo Chen, Hugh J. Clarke, Matteo Colombo, Pedro Daddario, David B. Damon, Christelle Depretz, Yves R. Dumond, Maria D. Grilli, Lu Han, Tim L. Houck, Amber M. Johnson, Kris N. Jones, Jörg Jung, Michel Leeman, Fangfang Liu, Cuong V. Lu, Emilio J. Mangual, Jade D. Nelson, Angela L. A. Puchlopek-Dermenci, Sally Gut Ruggeri, Paul A. Simonds, Barbara Sitter, Daniel E. Virtue, Shuguang Wang, Lixin Yu, Tao Yu
Publikováno v:
Organic Process Research & Development. 26:683-697
Autor:
Alexander Gontcharov, Peter Jones, Steven W. Kortum, David Pattavina, Seungwon Chung, Peter Robert Rose, Jotham Wadsworth Coe, Tim L. Houck, Javier Magano, Lacey Samp, Anil Rane
Publikováno v:
Organic Process Research & Development. 23:1990-2000
A scalable synthesis of a pan-JAK inhibitor is described. The original synthesis by the Medicinal Chemistry group has been modified to develop a new protecting group strategy, a 3-step telescoped s...
Autor:
David R. Bill, Ruggeri Sally G, Weston Neil Philip, Lulin Wei, Michael J. Castaldi, Tim L. Houck, Dennis E. Bourassa, David H. Brown Ripin
Publikováno v:
Organic Process Research & Development. 7:1043-1047
A scalable route to 5-(2-carboxy-pyridin-2-yloxy)-benz[1,2,5]oxadiazole (3) is demonstrated. The synthesis was designed to minimize potential safety issues with a previously practiced route and, in particular, to avoid the handling of 5-hydroxybenzof