Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Tim J. Vickers"'
Autor:
Alaullah Sheikh, Brunda Tumala, Tim J. Vickers, John C. Martin, Bruce A. Rosa, Subrata Sabui, Supratim Basu, Rita D. Simoes, Makedonka Mitreva, Chad Storer, Erik Tyksen, Richard D. Head, Wandy Beatty, Hamid M. Said, James M. Fleckenstein
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)
Enterotoxigenic Escherichia coli infections have been linked to non-diarrheal sequelae however, the reasons for this are unclear. Here, the authors present an additional role of heat-labile toxin in disrupting the structure and function of intestinal
Externí odkaz:
https://doaj.org/article/9487c8f48bd141909b0d137d3a8d5e13
Autor:
Alaullah Sheikh, Brunda Tumala, Tim J. Vickers, John C. Martin, Bruce A. Rosa, Subrata Sabui, Supratim Basu, Rita D. Simoes, Makedonka Mitreva, Chad Storer, Erik Tyksen, Richard D. Head, Wandy Beatty, Hamid M. Said, James M. Fleckenstein
EnterotoxigenicE. coli(ETEC), produce heat-labile (LT) and/or heat-stable (ST) enterotoxins, and are a common cause of diarrhea in children of resource-poor regions. ETEC have also been linked repeatedly to poorly understood sequelae including entero
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0615e8034874c146ac5b6d3996c1729f
https://doi.org/10.1101/2022.08.24.504189
https://doi.org/10.1101/2022.08.24.504189
Autor:
David M. Alvarado, Firdausi Qadri, Bernhard B. Singer, Tim J. Vickers, Matthew A. Ciorba, James M. Fleckenstein, Brunda Tumala, Alaullah Sheikh, Taufiqur Rahman Bhuiyan
Publikováno v:
Proceedings of the National Academy of Sciences. 117:29055-29062
The enterotoxigenic Escherichia coli (ETEC) are among the most common causes of diarrheal illness and death due to diarrhea among young children in low-/middle-income countries (LMICs). ETEC have also been associated with important sequelae including
Autor:
Tim J. Vickers, S. van der Post, Tamding Wangdi, Rita D. Simoes, Seonyoung Kim, Alaullah Sheikh, B. Aaron, C. Herring, Mark J. Miller, M. P. Palmer, Jeffrey C. Gildersleeve, J. A. Crainic, James M. Fleckenstein, Gunnar C. Hansson
EnterotoxigenicEscherichia coli(ETEC) are a genetically diverse pathologic variant ofE. colidefined by the production of heat-labile (LT) and/or heat-stable (ST) toxins. ETEC are estimated to cause hundreds of millions of cases of diarrheal illness a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2b7cc00ac720ec0202f7e15aa19d82c9
https://doi.org/10.1101/2021.10.22.465536
https://doi.org/10.1101/2021.10.22.465536
Autor:
Heather Wenzel, A. Louis Bourgeois, Doug Molina, Sachin Mani, Tim J. Vickers, Arlo Randall, Michael J. Darsley, James M. Fleckenstein, Philip L. Felgner, R. Reid Townsend, Petra Gilmore, David A. Rasko, Subhra Chakraborty, Xiaowu Liang, Jessica Brubaker, Clayton Harro, Barbara DeNearing, David A. Sack
Publikováno v:
npj Vaccines, Vol 4, Iss 1, Pp 1-9 (2019)
Enterotoxigenic Escherichia coli (ETEC) infections are a common cause of severe diarrheal illness in low- and middle-income countries. The live-attenuated ACE527 ETEC vaccine, adjuvanted with double mutant heat-labile toxin (dmLT), affords clear but
Autor:
Alaullah, Sheikh, Brunda, Tumala, Tim J, Vickers, David, Alvarado, Matthew A, Ciorba, Taufiqur Rahman, Bhuiyan, Firdausi, Qadri, Bernhard B, Singer, James M, Fleckenstein
Publikováno v:
Proc Natl Acad Sci U S A
The enterotoxigenic Escherichia coli (ETEC) are among the most common causes of diarrheal illness and death due to diarrhea among young children in low-/middle-income countries (LMICs). ETEC have also been associated with important sequelae including
Autor:
Elizabeth Cebelinski, Tim J. Vickers, Madeline Pashos, F. Matthew Kuhlmann, John Martin, Firdausi Qadri, Makedonka Mitreva, Oscar G. Gómez-Duarte, Pablo C. Okhuysen, Felipe Del Canto, James M. Fleckenstein, Dave Boxrud, David A. Rasko, Tracy H. Hazen, Roberto Vidal
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 13, Iss 11, p e0007825 (2019)
PLoS Neglected Tropical Diseases
PLoS Neglected Tropical Diseases
Background Enterotoxigenic Escherichia coli (ETEC) cause significant diarrheal morbidity and mortality in children of resource-limited regions, warranting development of effective vaccine strategies. Genetic diversity of the ETEC pathovar has impeded
Autor:
Heather Wenzel, Doug Molina, Petra Gilmore, James M. Fleckenstein, Subhra Chakraborty, A. Louis Bourgeois, Xiaowu Liang, David A. Sack, Raymond R. Townsend, Philip L. Felgner, Tim J. Vickers, Jessica Brubaker, Barbara DeNearing, Arlo Randall, Clayton Harro, David A. Rasko, Michael J. Darsley, Sachin Mani
Publikováno v:
The Journal of Infectious Diseases. 218:1436-1446
Background Enterotoxigenic Escherichia coli (ETEC) is a major cause of diarrheal illness in the developing world. Enterotoxigenic E coli vaccinology has been challenged by genetic diversity and heterogeneity of canonical antigens. Examination of the
Autor:
Jon W Huss, Camilo Orozco, James Goodale, Chunlei Wu, Serge Batalov, Tim J Vickers, Faramarz Valafar, Andrew I Su
Publikováno v:
PLoS Biology, Vol 6, Iss 7, p e175 (2008)
Externí odkaz:
https://doaj.org/article/6598c79cd94f4f018c2f99b028cf1c15
Autor:
Subhra, Chakraborty, Arlo, Randall, Tim J, Vickers, Doug, Molina, Clayton D, Harro, Barbara, DeNearing, Jessica, Brubaker, David A, Sack, A Louis, Bourgeois, Philip L, Felgner, Xiaowu, Liang, Sachin, Mani, Heather, Wenzel, R Reid, Townsend, Petra E, Gilmore, Michael J, Darsley, David A, Rasko, James M, Fleckenstein
Publikováno v:
NPJ Vaccines
Enterotoxigenic Escherichia coli (ETEC) infections are a common cause of severe diarrheal illness in low- and middle-income countries. The live-attenuated ACE527 ETEC vaccine, adjuvanted with double mutant heat-labile toxin (dmLT), affords clear but