Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Tim J. Schuijt"'
Autor:
Sukanya Narasimhan, Tim J. Schuijt, Nabil M. Abraham, Nallakkandi Rajeevan, Jeroen Coumou, Morven Graham, Andrew Robson, Ming-Jie Wu, Sirlei Daffre, Joppe W. Hovius, Erol Fikrig
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-17 (2017)
Borrelia burgdorferi, the causative agent of Lyme disease, is transmitted by the tick Ixodes scapularis. Here, the authors show that a tick secreted protein (PIXR) modulates the tick gut microbiota and facilitates B. burgdorferi colonization.
Externí odkaz:
https://doaj.org/article/f8125e0a31f24597bc975085a2deecbb
Autor:
Koen M. van der Sluijs, Esmée A. Bakker, Tim J. Schuijt, Jayaraj Joseph, Maryam Kavousi, Geert-Jan Geersing, Frans H. Rutten, Yvonne A. W. Hartman, Dick H. J. Thijssen, Thijs M. H. Eijsvogels
Publikováno v:
American Journal of Physiology : Heart and Circulatory Physiology, 324, H47-H56
American Journal of Physiology-Heart and Circulatory Physiology, 324(1), H47-H56. American Physiological Society
American Journal of Physiology : Heart and Circulatory Physiology, 324, 1, pp. H47-H56
American Journal of Physiology-Heart and Circulatory Physiology, 324(1), H47-H56. American Physiological Society
American Journal of Physiology : Heart and Circulatory Physiology, 324, 1, pp. H47-H56
Item does not contain fulltext Coronavirus disease 2019 (COVID-19) is reported to have long-term effects on cardiovascular health and physical functioning, even in the nonhospitalized population. The physiological mechanisms underlying these long-ter
Autor:
Wil F. Kopatz, Cornelis van 't Veer, J. Arnoud Marquart, Joost C. M. Meijers, Tom van der Poll, Mettine H.A. Bos, Priyanka Sharma, Gerry A. F. Nicolaes, Tim J. Schuijt, Tilman M. Hackeng, Daniëlle Kruijswijk, Anja Maag
Publikováno v:
Journal of Thrombosis and Haemostasis
Journal of thrombosis and haemostasis, 19(7), 1697-1708. Wiley-Blackwell
Journal of Thrombosis and Haemostasis, 19(7), 1697-1708. WILEY
Journal of Thrombosis and Haemostasis, 19(7), 1697-1708. Wiley
Journal of thrombosis and haemostasis, 19(7), 1697-1708. Wiley-Blackwell
Journal of Thrombosis and Haemostasis, 19(7), 1697-1708. WILEY
Journal of Thrombosis and Haemostasis, 19(7), 1697-1708. Wiley
Background The prothrombinase complex consists of factors Xa (FXa) and Va (FVa) on an anionic phospholipid surface and converts prothrombin into thrombin. Both coagulation factors require activation before complex assembly. We recently identified TIX
Autor:
Kaj Brouwers, Anne Sophie Kruit, Dominique van Midden, Sanna R. Rijpma, Tim J. Schuijt, Erik J. Koers, Her J. H. Zegers, Stefan Hummelink, Dietmar J. O. Ulrich
Publikováno v:
Plastic and Reconstructive Surgery, 150, 1, pp. 81-90
Plastic and Reconstructive Surgery, 150, 81-90
Plastic and Reconstructive Surgery, 150, 81-90
Item does not contain fulltext BACKGROUND: There is a risk for thrombotic complications (2 to 5 percent) associated with microsurgical reconstruction. Current thrombolytic therapy has a salvage rate between 60 and 70 percent, but it is afflicted by b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8dae11d0e3a607d592466102d1c25d50
https://repository.ubn.ru.nl/handle/2066/251619
https://repository.ubn.ru.nl/handle/2066/251619
Autor:
Clint van Duren, Saskia E M Schols, Tim J Schuijt, Joline L Saes, Suzanne A M Zegers, Y. Smit, Waander L. van Heerde
Publikováno v:
Haemophilia, 26, 269-277
Haemophilia
Haemophilia, 26, 2, pp. 269-277
Haemophilia
Haemophilia, 26, 2, pp. 269-277
Contains fulltext : 218269.pdf (Publisher’s version ) (Open Access) INTRODUCTION: The diagnostic trajectory of patients with increased bleeding tendency can be very costly and time-consuming. In addition, previous studies have shown that half of th
Publikováno v:
PLoS Pathogens, Vol 10, Iss 8, p e1004278 (2014)
Borrelia burgdorferi transmission to the vertebrate host commences with growth of the spirochete in the tick gut and migration from the gut to the salivary glands. This complex process, involving intimate interactions of the spirochete with the gut e
Externí odkaz:
https://doaj.org/article/44d4cb67e4e046ca998e3db286758127
Autor:
Wil F. Kopatz, Tom van der Poll, Nienke van Rein, Stella Thomassen, Anja Maag, Rodney M. Camire, Mettine H.A. Bos, Tilman M. Hackeng, Tim J. Schuijt, Daniëlle Kruijswijk, Joost C. M. Meijers, Cornelis van 't Veer
Publikováno v:
Journal of thrombosis and haemostasis. Wiley-Blackwell
Journal of Thrombosis and Haemostasis, 20(2), 328-338. Wiley
Journal of Thrombosis and Haemostasis, 20(2), 328-338. WILEY
Journal of Thrombosis and Haemostasis, 20(2), 328-338. Wiley
Journal of Thrombosis and Haemostasis, 20(2), 328-338. WILEY
Objective: Plasma thrombin generation (TG) provides important information on coagulation status; however, current TG output parameters do not predict major bleeding of patients on anticoagulants. We recently reported that factor V (FV) activation by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09aa79ddd5efbfe74687e858cf3df762
https://pure.amc.nl/en/publications/major-bleeding-during-oral-anticoagulant-therapy-associated-with-factor-v-activation-by-factor-xa(af4a4f98-184f-4181-9cd0-44c5218b3a60).html
https://pure.amc.nl/en/publications/major-bleeding-during-oral-anticoagulant-therapy-associated-with-factor-v-activation-by-factor-xa(af4a4f98-184f-4181-9cd0-44c5218b3a60).html
Autor:
Tim J Schuijt, Sukanya Narasimhan, Sirlei Daffre, Kathleen DePonte, Joppe W R Hovius, Cornelis Van't Veer, Tom van der Poll, Kamran Bakhtiari, Joost C M Meijers, Eric T Boder, Alje P van Dam, Erol Fikrig
Publikováno v:
PLoS ONE, Vol 6, Iss 1, p e15926 (2011)
Repeated exposure of rabbits and other animals to ticks results in acquired resistance or immunity to subsequent tick bites and is partially elicited by antibodies directed against tick antigens. In this study we demonstrate the utility of a yeast su
Externí odkaz:
https://doaj.org/article/e8a59f8366f542689f5da9feb4f453f7
Publikováno v:
Family Practice, 35, 179-185
Family Practice, 35, 2, pp. 179-185
Family Practice, 35, 2, pp. 179-185
Background Bacterial resistance to antibiotics represents a serious global challenge that is associated with high morbidity and mortality. One of the most important causes of this threat is antibiotic overuse. The Dutch College of General Practitione
Autor:
Onno J. de Boer, Alex Wagemakers, Tim J. Schuijt, Jeroen Coumou, Anneke Oei, Jasmin I. Ersoz, Erol Fikrig, Joris J. T. H. Roelofs, Joppe W. Hovius, Sukanya Narasimhan
Publikováno v:
Scientific Reports, 9
Scientific Reports
Scientific reports, 9(1):1431. Nature Publishing Group
Scientific Reports, Vol 9, Iss 1, Pp 1-11 (2019)
Scientific Reports
Scientific reports, 9(1):1431. Nature Publishing Group
Scientific Reports, Vol 9, Iss 1, Pp 1-11 (2019)
The causative agents of Lyme borreliosis, spirochetes belonging to the Borrelia burgdorferi sensu lato group, have developed several ways to protect themselves against killing by the host complement system. In addition, it has been shown that serum s