Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Tim I. Tree"'
Autor:
Ricardo C. Ferreira, Xaquin Castro Dopico, João J. Oliveira, Daniel B. Rainbow, Jennie H. Yang, Dominik Trzupek, Sarah A. Todd, Mhairi McNeill, Maristella Steri, Valeria Orrù, Edoardo Fiorillo, Daniel J. M. Crouch, Marcin L. Pekalski, Francesco Cucca, Tim I. Tree, Tim J. Vyse, Linda S. Wicker, John A. Todd
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
In systemic lupus erythematosus (SLE), perturbed immunoregulation underpins a pathogenic imbalance between regulatory and effector CD4+ T-cell activity. However, to date, the characterization of the CD4+ regulatory T cell (Treg) compartment in SLE ha
Externí odkaz:
https://doaj.org/article/491641df1e794e1fa267f30eab0edc3f
Autor:
John A Todd, Marina Evangelou, Antony J Cutler, Marcin L Pekalski, Neil M Walker, Helen E Stevens, Linsey Porter, Deborah J Smyth, Daniel B Rainbow, Ricardo C Ferreira, Laura Esposito, Kara M D Hunter, Kevin Loudon, Kathryn Irons, Jennie H Yang, Charles J M Bell, Helen Schuilenburg, James Heywood, Ben Challis, Sankalpa Neupane, Pamela Clarke, Gillian Coleman, Sarah Dawson, Donna Goymer, Katerina Anselmiova, Jane Kennet, Judy Brown, Sarah L Caddy, Jia Lu, Jane Greatorex, Ian Goodfellow, Chris Wallace, Tim I Tree, Mark Evans, Adrian P Mander, Simon Bond, Linda S Wicker, Frank Waldron-Lynch
Publikováno v:
PLoS Medicine, Vol 13, Iss 10, p e1002139 (2016)
BackgroundInterleukin-2 (IL-2) has an essential role in the expansion and function of CD4+ regulatory T cells (Tregs). Tregs reduce tissue damage by limiting the immune response following infection and regulate autoreactive CD4+ effector T cells (Tef
Externí odkaz:
https://doaj.org/article/ce713b3d60664d62831f35693cfd7b82