Zobrazeno 1 - 10
of 72
pro vyhledávání: '"Tim Hofer"'
Publikováno v:
Environment International, Vol 155, Iss , Pp 106592- (2021)
When building the novel public mammalian toxicokinetic database (MamTKDB) we collected and included 3927 elimination half-lives (elimt1/2) for 1407 xenobiotics in various species (rat, human, mouse, dog, monkey, rabbit, cattle, pig, sheep, guinea pig
Externí odkaz:
https://doaj.org/article/78810556d1a54d489790a1edccfb2271
Autor:
Yuqing Zhang, Tianyu Dong, Weiyue Hu, Xu Wang, Bo Xu, Zhongning Lin, Tim Hofer, Pawel Stefanoff, Ying Chen, Xinru Wang, Yankai Xia
Publikováno v:
Environment International, Vol 123, Iss , Pp 325-336 (2019)
Background: The evaluation of the chemical impact on human health is usually constrained to the analysis of the health effects of exposure to a single chemical or a group of similar chemicals at one time. The effects of chemical mixtures are seldom a
Externí odkaz:
https://doaj.org/article/7560c1e1f8824df0aab012c82323ce62
Publikováno v:
Biomolecules, Vol 12, Iss 5, p 714 (2022)
Disruption of cerebral iron regulation appears to have a role in aging and in the pathogenesis of various neurodegenerative disorders. Possible unfavorable impacts of iron accumulation include reactive oxygen species generation, induction of ferropto
Externí odkaz:
https://doaj.org/article/4706b2c9cc26435da025c85e9d8d7171
Autor:
Hanne Friis Berntsen, Nur Duale, Cesilie Granum Bjørklund, Oscar Daniel Rangel-Huerta, Kine Dyrberg, Tim Hofer, Kirsten Eline Rakkestad, Gunn Østby, Ruth Halsne, Gudrun Boge, Ragnhild Elisabeth Paulsen, Oddvar Myhre, Erik Ropstad
Publikováno v:
Environment International, Vol 146, Iss , Pp 106240- (2021)
Exposure to persistent organic pollutants (POPs), encompassing chlorinated (Cl), brominated (Br) and perfluoroalkyl acid (PFAA) compounds is associated with adverse neurobehaviour in humans and animals, and is observed to cause adverse effects in ner
Externí odkaz:
https://doaj.org/article/964b782e25cd440a97fad1469be9d1e1
Autor:
Vicente Mustieles, Shereen Cynthia D'Cruz, Stephan Couderq, Andrea Rodríguez-Carrillo, Jean-Baptiste Fini, Tim Hofer, Inger-Lise Steffensen, Hubert Dirven, Robert Barouki, Nicolás Olea, Mariana F. Fernández, Arthur David
Publikováno v:
Environment International, Vol 144, Iss , Pp 105811- (2020)
Human biomonitoring (HBM) studies have demonstrated widespread and daily exposure to bisphenol A (BPA). Moreover, BPA structural analogues (e.g. BPS, BPF, BPAF), used as BPA replacements, are being increasingly detected in human biological matrices.
Externí odkaz:
https://doaj.org/article/327a077640cd40179f790362185b9a0b
Publikováno v:
Journal of Clinical and Translational Science, Vol 5, Pp 122-123 (2021)
ABSTRACT IMPACT: Grouping patients with potentially high intensity specialty care needs based on their propensity for healthcare continuity patterns can inform the development of personalized care coordination and care navigation interventions OBJECT
Externí odkaz:
https://doaj.org/article/03c1a113cf8f433b94836fdef52b957a
Autor:
Tim Hofer
Publikováno v:
Antioxidants, Vol 10, Iss 8, p 1159 (2021)
This Special Issue (same name as title) focuses on human exposure to foreign chemicals (xenobiotics) that cause oxidative stress [...]
Externí odkaz:
https://doaj.org/article/8900eb421c8840fd92af5ed91e052665
Publikováno v:
Antioxidants, Vol 10, Iss 6, p 824 (2021)
Neuromelanin (NM) accumulates in catecholamine long-lived brain neurons that are lost in neurodegenerative diseases. NM is a complex substance made of melanic, peptide and lipid components. NM formation is a natural protective process since toxic end
Externí odkaz:
https://doaj.org/article/fd930e8613144e91a3b772c663219e7e
Autor:
Tim Hofer, Ragnar Ludvig Olsen
Publikováno v:
Bioingeniøren, Vol 45, Iss 10, Pp 6-12 (2010)
Background: Several medical conditions involve increased lipid peroxidation where free radicals damage cellular membranes. Unsaturated fatty acids oxidize in presence of oxygen after initiation by peroxides in presence of transition metals such as ir
Externí odkaz:
https://doaj.org/article/73efe6ee649e4d15ab8a75875eb04df3
Autor:
Asimina Hiona, Alberto Sanz, Gregory C Kujoth, Reinald Pamplona, Arnold Y Seo, Tim Hofer, Shinichi Someya, Takuya Miyakawa, Chie Nakayama, Alejandro K Samhan-Arias, Stephane Servais, Jamie L Barger, Manuel Portero-Otín, Masaru Tanokura, Tomas A Prolla, Christiaan Leeuwenburgh
Publikováno v:
PLoS ONE, Vol 5, Iss 7, p e11468 (2010)
Aging results in a progressive loss of skeletal muscle, a condition known as sarcopenia. Mitochondrial DNA (mtDNA) mutations accumulate with aging in skeletal muscle and correlate with muscle loss, although no causal relationship has been established
Externí odkaz:
https://doaj.org/article/56ed913504f041fc9522b7a927c5d1cc