Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Tim Haymes"'
Autor:
Sarah Dugdale, Ian Yule, Anthony R Knight, Chen I-Jen, Tim Haymes, Sean Lightowler, Heather Simmonite, Mike Comer, Anthony Padfield, Teresa Brooks, Allan M. Jordan, A Misra, Guy A. Kennett, Angela Merrett, Simon Bedford, K Benwell, Melanie Wong, Karine G. Poullennec, Loic LeStrat, Mark Reece, Burkhard Klenke
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 19:5945-5949
We herein report the discovery of a novel class of antagonists of the human adenosine A2B receptor. This low molecular weight scaffold has been optimized to offer derivatives with potential utility for the alleviation of conditions associated with th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6cca22fbb50c8948de07dce59be48f66
https://doi.org/10.1016/j.bmcl.2009.08.040
https://doi.org/10.1016/j.bmcl.2009.08.040
Autor:
Alexandra Clay, Philip Stephen Jackson, Heather Simmonite, Howard Langh Am Mansell, Richard S. Todd, Ian Yule, Samantha J Bamford, Mona Saadi, Tim Haymes, Stefania Leonardi, Burlchard Klenke, Douglas S. Williamson, Gemma Caroline Stratton, Allan M. Jordan, Jeanette Liu, Suneel Gaur, Roger John Gillespie, Sean Ng
Publikováno v:
Bioorganicmedicinal chemistry. 17(18)
Antagonists of the human A2A receptor have been reported to have potential therapeutic benefit in the alleviation of the symptoms associated with neurodegenerative movement disorders such as Parkinson’s disease. As part of our efforts to discover p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf4a87a3b0742c08b5dafe9adaff4d1b
https://pubmed.ncbi.nlm.nih.gov/19695884
https://pubmed.ncbi.nlm.nih.gov/19695884