Zobrazeno 1 - 10
of 89
pro vyhledávání: '"Tim Hassall"'
Autor:
Sarah M. Trinder, Campbell McKay, Phoebe Power, Monique Topp, Bosco Chan, Santosh Valvi, Geoffrey McCowage, Dinisha Govender, Maria Kirby, David S. Ziegler, Neevika Manoharan, Tim Hassall, Stewart Kellie, John Heath, Frank Alvaro, Paul Wood, Stephen Laughton, Karen Tsui, Andrew Dodgshun, David D. Eisenstat, Raelene Endersby, Stephen J. Luen, Eng-Siew Koh, Hao-Wen Sim, Benjamin Kong, Nicholas G. Gottardo, James R. Whittle, Dong-Anh Khuong-Quang, Jordan R. Hansford
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
The mitogen-activated protein kinase (MAPK) pathway signaling pathway is one of the most commonly mutated pathways in human cancers. In particular, BRAF alterations result in constitutive activation of the rapidly accelerating fibrosarcoma–extracel
Externí odkaz:
https://doaj.org/article/b70dc0b5bc9c4f5f8e61a5acca858e20
Autor:
Brooke E. Kohler, Emmah Baque, Carolina X. Sandler, Denise S. K. Brookes, Caroline O. Terranova, Matthew Rixon, Tim Hassall, Stewart G. Trost
Publikováno v:
BMC Pediatrics, Vol 21, Iss 1, Pp 1-11 (2021)
Abstract Background Posterior fossa brain tumors (PFBT) are the most common solid tumor in children. Recent increases in survival rates are encouraging; however, survivors may experience a plethora of disease- and treatment-related complications that
Externí odkaz:
https://doaj.org/article/880516c754234ddd946d2dc98bc291d4
Autor:
Anthony P. Y. Liu, Sandeep K. Dhanda, Tong Lin, Edgar Sioson, Aksana Vasilyeva, Brian Gudenas, Ruth G. Tatevossian, Sujuan Jia, Geoffrey Neale, Daniel C. Bowers, Tim Hassall, Sonia Partap, John R. Crawford, Murali Chintagumpala, Eric Bouffet, Geoff McCowage, Alberto Broniscer, Ibrahim Qaddoumi, Greg Armstrong, Karen D. Wright, Santhosh A. Upadhyaya, Anna Vinitsky, Christopher L. Tinkle, John Lucas, Jason Chiang, Daniel J. Indelicato, Robert Sanders, Paul Klimo, Frederick A. Boop, Thomas E. Merchant, David W. Ellison, Paul A. Northcott, Brent A. Orr, Xin Zhou, Arzu Onar-Thomas, Amar Gajjar, Giles W. Robinson
Publikováno v:
Acta Neuropathologica. 144:733-746
Methylation profiling has radically transformed our understanding of tumors previously called central nervous system primitive neuro-ectodermal tumors (CNS-PNET). While this marks a momentous step toward defining key differences, reclassification has
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de637cda9026768842fa1f9a26a7ce19
https://doi.org/10.1007/s00401-022-02484-7
https://doi.org/10.1007/s00401-022-02484-7
Autor:
Amar Gajjar, David W. Ellison, Marcel Kool, Thomas E. Merchant, Frederick A. Boop, Kim E. Nichols, Daniel J. Indelicato, Zoltan Patay, Paul Klimo, Robert P. Sanders, Roya Mostafavi, Sridharan Gururangan, Eric Bouffet, Murali Chintagumpala, John R. Crawford, Paul G. Fisher, Sonia Partap, Tim Hassall, Anne E. Bendel, Gregory T. Armstrong, Anna Vinitsky, Ibrahim Qaddoumi, Alberto Broniscer, Ashok Srinivasan, Sandeep Kumar Dhanda, Ruth G. Tatevossian, Catherine A. Billups, Gang Wu, Pascal Johann, Brent A. Orr, Arzu Onar-Thomas, Giles W. Robinson, Santhosh A. Upadhyaya
Supplementary Figures S1 to S5
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::126a7d0e9a9a0e98aa4e6e8e91ef267e
https://doi.org/10.1158/1078-0432.22478771
https://doi.org/10.1158/1078-0432.22478771
Autor:
Amar Gajjar, David W. Ellison, Marcel Kool, Thomas E. Merchant, Frederick A. Boop, Kim E. Nichols, Daniel J. Indelicato, Zoltan Patay, Paul Klimo, Robert P. Sanders, Roya Mostafavi, Sridharan Gururangan, Eric Bouffet, Murali Chintagumpala, John R. Crawford, Paul G. Fisher, Sonia Partap, Tim Hassall, Anne E. Bendel, Gregory T. Armstrong, Anna Vinitsky, Ibrahim Qaddoumi, Alberto Broniscer, Ashok Srinivasan, Sandeep Kumar Dhanda, Ruth G. Tatevossian, Catherine A. Billups, Gang Wu, Pascal Johann, Brent A. Orr, Arzu Onar-Thomas, Giles W. Robinson, Santhosh A. Upadhyaya
Purpose:Report relevance of molecular groups to clinicopathologic features, germline SMARCB1/SMARCA4 alterations (GLA), and survival of children with atypical teratoid rhabdoid tumor (ATRT) treated in two multi-institutional clinical trials.Materials
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b29fb4f16e48c14f46b5194fc53bbec
https://doi.org/10.1158/1078-0432.c.6530039
https://doi.org/10.1158/1078-0432.c.6530039
Autor:
Amar Gajjar, David W. Ellison, Marcel Kool, Thomas E. Merchant, Frederick A. Boop, Kim E. Nichols, Daniel J. Indelicato, Zoltan Patay, Paul Klimo, Robert P. Sanders, Roya Mostafavi, Sridharan Gururangan, Eric Bouffet, Murali Chintagumpala, John R. Crawford, Paul G. Fisher, Sonia Partap, Tim Hassall, Anne E. Bendel, Gregory T. Armstrong, Anna Vinitsky, Ibrahim Qaddoumi, Alberto Broniscer, Ashok Srinivasan, Sandeep Kumar Dhanda, Ruth G. Tatevossian, Catherine A. Billups, Gang Wu, Pascal Johann, Brent A. Orr, Arzu Onar-Thomas, Giles W. Robinson, Santhosh A. Upadhyaya
Germline methodology
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13bef37eeec39cfa3a98bf2f3a814022
https://doi.org/10.1158/1078-0432.22478768
https://doi.org/10.1158/1078-0432.22478768
Autor:
Allison L Bartlett, Adam Lane, Brooklyn Chaney, Nancy Yanez Escorza, Katie Black, Anne Cochrane, Jane Minturn, Ute Bartels, Kathy Warren, Jordan Hansford, David Ziegler, Blanca Diez, Stewart Goldman, Roger Packer, Mark Kieran, Mariko DeWire-Schottmiller, Craig Erker, Michelle Monje-Deisseroth, Lars Wagner, Carl Koschmann, Kathleen Dorris, Chie-Schin Shih, Tim Hassall, Yvan Samson, Paul Fisher, Stacie S Wang, Karen Tsui, Gustavo Sevlever, Xiaoting Zhu, Phillip Dexheimer, Anthony Asher, Christine Fuller, Rachid Drissi, Blaise Jones, James Leach, Maryam Fouladi
Publikováno v:
Neuro Oncol
Background Children ≤36 months with diffuse intrinsic pontine glioma (DIPG) have increased long-term survival (LTS, overall survival (OS) ≥24 months). Understanding distinguishing characteristics in this population is critical to improving outcom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f4fb3bcd22850a5008dff65bb3bb3f7
https://doi.org/10.1093/neuonc/noac123
https://doi.org/10.1093/neuonc/noac123
Autor:
Ira J Dunkel, François Doz, Nicholas K Foreman, Darren Hargrave, Alvaro Lassaletta, Nicolas André, Jordan R Hansford, Tim Hassall, Matthias Eyrich, Sridharan Gururangan, Ute Bartels, Amar Gajjar, Lisa Howell, Deepti Warad, Misena Pacius, Rachel Tam, Yu Wang, Li Zhu, Kenneth Cohen
Publikováno v:
Neuro-Oncology.
Background Therapeutic options are limited in pediatric CNS malignancies. CheckMate 908 (NCT03130959) is an open-label, sequential-arm, phase 1b/2 study investigating nivolumab (NIVO) and NIVO + ipilimumab (IPI) in pediatric patients with high-grade
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f076d6d7f3a01fa38775d857a08f6008
https://doi.org/10.1093/neuonc/noad031
https://doi.org/10.1093/neuonc/noad031
Autor:
Marija Kojic, Mellissa K Maybury, Nicola Waddell, Lambros T Koufariotis, Venkateswar Addala, Amanda Millar, Scott Wood, John V Pearson, Jordan R Hansford, Tim Hassall, Brandon J Wainwright
Publikováno v:
Neuro-Oncology.
Background Brain cancer is the leading cause of cancer-related death in children. Early detection and serial monitoring are essential for better therapeutic outcomes. Liquid biopsy has recently emerged as a promising approach for detecting these tumo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7206558149ba4e749d2e83ec1ae295e8
https://doi.org/10.1093/neuonc/noad032
https://doi.org/10.1093/neuonc/noad032
Autor:
Jane E. Minturn, Ayman El-Sheikh, Gustavo Sevlever, Michelle Monje-Deisseroth, Hetal Dholaria, Karen Tsui, Maryam Fouladi, Pratiti Bandopadhayay, Cynthia Hawkins, Scott L Coven, Lindsay Kilburn, Christopher L. Tinkle, David S. Ziegler, Eric Sandler, Yvan Samson, Jordan R. Hansford, Eric Bouffet, Sylvia Cheng, Sridharan Gururangan, Kathleen Dorris, Tim Hassall, Mohamed S. Zaghloul, Carl Koschmann, Sarah Leary, Mercedes Garcia Lombardi, Blaise V. Jones, Paul G. Fisher, Anthony Asher, Rachid Drissi, Blanca Diez, Kenneth J. Cohen, Jie Ma, Adriana Fonseca, Katie Black, Nicholas G. Gottardo, Stewart Goldman, Christine E. Fuller, Tabitha Cooney, Moatasem El-Ayadi, Adam Lane, Brooklyn Chaney, Mariko DeWire, Robert J. Greiner, Ute Bartels, Margot A Lazow, James L. Leach, Lars M. Wagner, Roger J. Packer
Publikováno v:
Neuro Oncol
Background Diffuse intrinsic pontine glioma (DIPG) remains a clinico-radiologic diagnosis without routine tissue acquisition. Reliable imaging distinction between DIPG and other pontine tumors with potentially more favorable prognoses and treatment c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1eb93f7f10aea819afa4cbaa267e360e
https://doi.org/10.1093/neuonc/noab245
https://doi.org/10.1093/neuonc/noab245