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pro vyhledávání: '"Tim H.M. Jonckers"'
Autor:
Serge Pieters, David McGowan, Florence Herschke, Frederik Pauwels, Bart Stoops, Stefaan Last, Werner Embrechts, Annick Scholliers, Wendy Mostmans, Kris Van Dijck, Bertrand Van Schoubroeck, Tine Thoné, Dorien De Pooter, Gregory Fanning, Mari Luz Rosauro, Mourad Daoubi Khamlichi, Ioannis Houpis, Eric Arnoult, Tim H.M. Jonckers, Pierre Raboisson
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 28:711-719
The discovery of a novel series of highly potent quinazoline TLR 7/8 agonists is described. The synthesis and structure-activity relationship is presented. Structural requirements and optimization of this series toward TLR 7 selectivity afforded the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ecb247545d952c5e2d61547d1061dea6
https://doi.org/10.1016/j.bmcl.2018.01.014
https://doi.org/10.1016/j.bmcl.2018.01.014
