Zobrazeno 1 - 10
of 430
pro vyhledávání: '"Tim H M Huang"'
Autor:
Fei Gu, Mark S Doderer, Yi-Wen Huang, Juan C Roa, Paul J Goodfellow, E Lynette Kizer, Tim H M Huang, Yidong Chen
Publikováno v:
PLoS ONE, Vol 8, Iss 4, p e60980 (2013)
DNA methylation of promoter CpG islands is associated with gene suppression, and its unique genome-wide profiles have been linked to tumor progression. Coupled with high-throughput sequencing technologies, it can now efficiently determine genome-wide
Externí odkaz:
https://doaj.org/article/ccc398d9810e4ed0a84d5b8090d4497b
Autor:
Diego Villar, Amaya Ortiz-Barahona, Laura Gómez-Maldonado, Nuria Pescador, Fátima Sánchez-Cabo, Hubert Hackl, Benjamin A T Rodriguez, Zlatko Trajanoski, Ana Dopazo, Tim H M Huang, Pearlly S Yan, Luis Del Peso
Publikováno v:
PLoS ONE, Vol 7, Iss 9, p e45708 (2012)
The transcriptional response driven by Hypoxia-inducible factor (HIF) is central to the adaptation to oxygen restriction. Despite recent characterization of genome-wide HIF DNA binding locations and hypoxia-regulated transcripts in different cell typ
Externí odkaz:
https://doaj.org/article/76a9b84e250f465abfeb1ef0d1b247d2
Autor:
Mingxiang Teng, Curt Balch, Yunlong Liu, Meng Li, Tim H M Huang, Yadong Wang, Kenneth P Nephew, Lang Li
Publikováno v:
PLoS ONE, Vol 7, Iss 3, p e32928 (2012)
It is now established that, as compared to normal cells, the cancer cell genome has an overall inverse distribution of DNA methylation ("methylome"), i.e., predominant hypomethylation and localized hypermethylation, within "CpG islands" (CGIs). Moreo
Externí odkaz:
https://doaj.org/article/99abcbc490c04a4f91be6f24be444edc
Autor:
Guohua Wang, Yadong Wang, Changyu Shen, Yi-wen Huang, Kun Huang, Tim H M Huang, Kenneth P Nephew, Lang Li, Yunlong Liu
Publikováno v:
PLoS ONE, Vol 5, Iss 11, p e13798 (2010)
MicroRNAs are small non-coding RNAs involved in post-transcriptional regulation of gene expression. Due to the poor annotation of primary microRNA (pri-microRNA) transcripts, the precise location of promoter regions driving expression of many microRN
Externí odkaz:
https://doaj.org/article/7cd16091b5f84ef78b23eeaf8c97d375
Autor:
Chia-Nung Hung, Meizhen Chen, Daniel T. DeArmond, Cheryl H.-L. Chiu, Catherine A. Limboy, Xi Tan, Meena Kusi, Chih-Wei Chou, Li-Ling Lin, Zhao Zhang, Chiou-Miin Wang, Chun-Liang Chen, Kohzoh Mitsuya, Pawel A. Osmulski, Maria E. Gaczynska, Nameer B. Kirma, Ratna K. Vadlamudi, Don L. Gibbons, Steve Warner, Andrew J. Brenner, Daruka Mahadevan, Joel E. Michalek, Tim H.-M. Huang, Josephine A. Taverna
Publikováno v:
Cell Reports, Vol 42, Iss 9, Pp 113067- (2023)
Summary: Tumor-associated macrophages (TAMs) are integral to the development of complex tumor microenvironments (TMEs) and can execute disparate cellular programs in response to extracellular cues. However, upstream signaling processes underpinning t
Externí odkaz:
https://doaj.org/article/81e2c4bf9d664349a0f9840fc517001b
Autor:
Xiang Gu, Bingzhi Wang, Haiyan Zhu, You Zhou, Aaron M. Horning, Tim H-M Huang, Yidong Chen, Peter Houghton, Zhao Lai, Joel E. Michalek, Lu-Zhe Sun
Publikováno v:
Breast Cancer Research, Vol 22, Iss 1, Pp 1-15 (2020)
Abstract Background Aging is a comorbidity of breast cancer suggesting that aging-associated transcriptome changes may promote breast cancer progression. However, the mechanism underlying the age effect on breast cancer remains poorly understood. Met
Externí odkaz:
https://doaj.org/article/437e4e0e08814325a16b27c396b42ce4
Autor:
Chun-Lin Lin, Xi Tan, Meizhen Chen, Meena Kusi, Chia-Nung Hung, Chih-Wei Chou, Ya-Ting Hsu, Chiou-Miin Wang, Nameer Kirma, Chun-Liang Chen, Ching-Hung Lin, Kate I. Lathrop, Richard Elledge, Virginia G. Kaklamani, Kohzoh Mitsuya, Tim H.-M. Huang
Publikováno v:
BMC Medical Genomics, Vol 13, Iss 1, Pp 1-18 (2020)
Abstract Background Chromothripsis is an event of genomic instability leading to complex chromosomal alterations in cancer. Frequent long-range chromatin interactions between transcription factors (TFs) and targets may promote extensive translocation
Externí odkaz:
https://doaj.org/article/91f5a5e5bf7c4250aa876d533ff61028
Autor:
Gary D. Stoner, Wendy L. Frankel, Tim H.-M. Huang, Pengyuan Liu, Claire Seguin, Christine L. Sardo Molmenti, Chieh-Ti Kuo, Henrietta Hasson, Carol A. Burke, Li-Shu Wang
PDF file - 10KB, Supplemental Figure 2. Black raspberry (BRB) powder (A)and BRB suppository (B).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::458c30e769066fe13ae9f663f5aa56a8
https://doi.org/10.1158/1940-6207.22525475.v1
https://doi.org/10.1158/1940-6207.22525475.v1
Autor:
Gary D. Stoner, Wendy L. Frankel, Tim H.-M. Huang, Pengyuan Liu, Claire Seguin, Christine L. Sardo Molmenti, Chieh-Ti Kuo, Henrietta Hasson, Carol A. Burke, Li-Shu Wang
PDF file - 16KB, FAP Supplemental Figure 1, Study flow chart.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14b76b642064991a5b305c4c22ada8b0
https://doi.org/10.1158/1940-6207.22525481.v1
https://doi.org/10.1158/1940-6207.22525481.v1
Autor:
Gary D. Stoner, Wendy L. Frankel, Tim H.-M. Huang, Pengyuan Liu, Claire Seguin, Christine L. Sardo Molmenti, Chieh-Ti Kuo, Henrietta Hasson, Carol A. Burke, Li-Shu Wang
PDF file - 24KB, Supplemental Figure 3. APC mutations in 14 FAP patients.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02b65defc856060e572762ac825aa1f9
https://doi.org/10.1158/1940-6207.22525472
https://doi.org/10.1158/1940-6207.22525472