Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Tim H Gehrke"'
Autor:
Tim H. Gehrke, Thomas Carell, Peter Mayer, Amrei Deutsch, Ines Thoma, Hendrik Zipse, Sidney Becker
Publikováno v:
Science. 352:833-836
Making RNA in the prebiotic world The RNA World hypothesis posits that RNA was one of the first self-replicating molecules leading to the origin of life. The nucleotide bases of RNA—A, U, C, and G—are chemically complex, and it has been unclear h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1feb8e54fcc32dbd2983e6d04f4f1f8
https://doi.org/10.1126/science.aad2808
https://doi.org/10.1126/science.aad2808
Autor:
David S. Stephenson, Ulrike Lischke, Thomas Carell, Tim H. Gehrke, Sabine Schneider, Hendrik Zipse, Karola L. Gasteiger, Simone Arnold, Heiko Müller
Publikováno v:
Nature Chemical Biology. 9:455-461
8-Oxopurines (8-oxodG and 8-oxodA) and formamidopyrimidines (FaPydG and FaPydA) are major oxidative DNA lesions involved in cancer development and aging. Their mutagenicity is believed to result from a conformational shift of the N9-C1' glycosidic bo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed36330a09c9206cd36c34cee067fca0
https://doi.org/10.1038/nchembio.1254
https://doi.org/10.1038/nchembio.1254
Autor:
Tobias A. M. Gulder, Christoph Lambert, Alexander Heckmann, Thomas Kupfer, Krzysztof Radacki, Holger Braunschweig, Torsten Bruhn, Tim H Gehrke, Gerhard Bringmann, Daniel C. G. Götz
Publikováno v:
Journal of the American Chemical Society. 130:17812-17825
In this paper, the synthesis of a new type of intrinsically chiral, directly beta,beta'-linked, octa-meso-aryl-substituted bisporphyrins is described, by using an optimized Suzuki-Miyaura coupling procedure. This strategy leads to a broad variety of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de40857f3875dc6c50ea59f6c80689c7
https://doi.org/10.1021/ja8055886
https://doi.org/10.1021/ja8055886
Autor:
Pierre Aller, Tim H. Gehrke, Kadija Essalhi, Maria Angeles Izquierdo, Thomas Carell, Franck Coste, Bertrand Castaing, Françoise Culard, Yann-Vaï Le Bihan
Publikováno v:
Repositori Universitat Jaume I
Universitat Jaume I
Nucleic Acids Research
Nucleic Acids Research, Oxford University Press, 2011, 39 (14), pp.6277-6290. ⟨10.1093/nar/gkr215⟩
Universitat Jaume I
Nucleic Acids Research
Nucleic Acids Research, Oxford University Press, 2011, 39 (14), pp.6277-6290. ⟨10.1093/nar/gkr215⟩
International audience; DNA base-damage recognition in the base excision repair (BER) is a process operating on a wide variety of alkylated, oxidized and degraded bases. DNA glycosylases are the key enzymes which initiate the BER pathway by recognizi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::703822d61a58bc07cd4ed5b6ae03cc1b
http://hdl.handle.net/10234/41081
http://hdl.handle.net/10234/41081
