Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Tim Fieblinger"'
Autor:
Paul J. Lamothe-Molina, Andreas Franzelin, Lennart Beck, Dong Li, Lea Auksutat, Tim Fieblinger, Laura Laprell, Joachim Alhbeck, Christine E. Gee, Matthias Kneussel, Andreas K. Engel, Claus C. Hilgetag, Fabio Morellini, Thomas G. Oertner
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
In mice, reactivation of neurons that express cFos during fear conditioning induces a behavioural response. Here the authors show that cFos expression in mouse dentate gyrus shifts every day to different neurons, even during highly consistent spatial
Externí odkaz:
https://doaj.org/article/3533e982510d493eb9e861a533fcd010
Autor:
Tim Fieblinger
Publikováno v:
Frontiers in Human Neuroscience, Vol 15 (2021)
The striatum is a very heterogenous brain area, composed of different domains and compartments, albeit lacking visible anatomical demarcations. Two populations of striatal spiny projection neurons (SPNs) build the so-called direct and indirect pathwa
Externí odkaz:
https://doaj.org/article/d75dece44d0b46b983d7e9e1ac9e3c37
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 10, p 5470 (2022)
Non-apoptotic caspase-3 activation is critically involved in dendritic spine loss and synaptic dysfunction in Alzheimer’s disease. It is, however, not known whether caspase-3 plays similar roles in other pathologies. Using a mouse model of clinical
Externí odkaz:
https://doaj.org/article/e6929ad2398a462cb6887815c06c30b9
Publikováno v:
Neurobiology of Disease, Vol 105, Iss , Pp 117-131 (2017)
Striatal neurons forming the indirect pathway (iSPNs) are particularly vulnerable in Huntington's disease (HD). In this study we set out to investigate morphological and physiological alterations of iSPNs in two mouse models of HD with relatively slo
Externí odkaz:
https://doaj.org/article/4022ca194a44473993a15705fb31d781
Publikováno v:
F1000Research, Vol 7 (2018)
Authors of a recent paper demonstrate that, like ERMES (ER-mitochondria encounter structure) in fungal cells, PDZD8 (PDZ domain containing 8) tethers mitochondria to the ER in mammalian cells. However, identifying PDZD8 as a “functional ortholog”
Externí odkaz:
https://doaj.org/article/8afc6a497eed42d69fd920d333e163e2
Autor:
Alberto Perez-Alvarez, Tim Fieblinger, Thomas Oertner, Paul J. Lamothe-Molina, Christine E. Gee
Publikováno v:
EMBO reports. 23
The striatum is a subcortical brain region responsible for the initiation and termination of voluntary movements. Striatal spiny projection neurons receive major excitatory synaptic input from neocortex and thalamus, and cyclic nucleotides have long
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ab2501dbe3cddad57144360ec18be41
https://doi.org/10.15252/embr.202154361
https://doi.org/10.15252/embr.202154361
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 10; Pages: 5470
Non-apoptotic caspase-3 activation is critically involved in dendritic spine loss and synaptic dysfunction in Alzheimer’s disease. It is, however, not known whether caspase-3 plays similar roles in other pathologies. Using a mouse model of clinical
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=multidiscipl::412187d76d13ccda2801a26b758306f8
Autor:
Paul J. Lamothe-Molina, Andreas Franzelin, Lennart Beck, Dong Li, Lea Auksutat, Tim Fieblinger, Laura Laprell, Joachim Alhbeck, Christine E. Gee, Matthias Kneussel, Andreas K. Engel, Claus C. Hilgetag, Fabio Morellini, Thomas G. Oertner
Publikováno v:
Nature communications. 13(1)
Mice display signs of fear when neurons that express cFos during fear conditioning are artificially reactivated. This finding gave rise to the notion that cFos marks neurons that encode specific memories. Here we show that cFos expression patterns in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90aec1ec5ff32704e2c6edeb478cf412
https://pubmed.ncbi.nlm.nih.gov/36289226
https://pubmed.ncbi.nlm.nih.gov/36289226
Autor:
Paul J. Lamothe-Molina, Andreas Franzelin, Lennart Beck, Dong Li, Lea Auksutat, Tim Fieblinger, Laura Laprell, Joachim Alhbeck, Christine E. Gee, Matthias Kneussel, Andreas K. Engel, Claus C. Hilgetag, Fabio Morellini, Thomas G. Oertner
Transgenic cFos reporter mice are used to identify and manipulate neurons that store contextual information during fear learning. It is not clear, however, how spatial information acquired over several training days is integrated in the hippocampus.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ef4d61ecb94becc34c8e82cf5c8ff43c
https://doi.org/10.1101/2020.08.29.273391
https://doi.org/10.1101/2020.08.29.273391
