Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Tim Erkens"'
Autor:
Selina Khan, Sonia Marquez-Martinez, Tim Erkens, Adriaan de Wilde, Lea M. M. Costes, Petra Vinken, Sandra De Jonghe, Wendy Roosen, Chiara Talia, Ronnie Chamanza, Jan Serroyen, Jeroen Tolboom, Roland C. Zahn, Frank Wegmann
Publikováno v:
Vaccines, Vol 11, Iss 12, p 1792 (2023)
Vaccine-induced immune thrombotic thrombocytopenia (VITT) is a very rare but serious adverse reaction that can occur after Ad26.COV2.S vaccination in humans, leading to thrombosis at unusual anatomic sites. One hypothesis is that accidental intraveno
Externí odkaz:
https://doaj.org/article/bfc0bc02614c4b6aaebfac4c8308c882
Autor:
Nick Goeminne, Lieve Lammens, Ruud R.G. Bueters, Marjolein van Heerden, Rob J. Vreeken, Tim Erkens, Filip Cuyckens
Publikováno v:
Journal of Applied Toxicology. 38:1282-1292
The intestinal barrier controls intestinal permeability, and its disruption has been associated with multiple diseases. Therefore, preclinical safety biomarkers monitoring barrier integrity are essential during the development of drugs targeting the
Autor:
Bianca Feyen, Adriana Looszova, Tim Erkens, Jill Witters, Liesbeth Van den Sande, Filip Verbraeken
Publikováno v:
Veterinary Clinical Pathology. 46:416-421
BACKGROUND A marked decrease in thrombocyte count was observed between subsequent measurements of the same EDTA blood sample in several minipigs, but little information was available explaining this finding. OBJECTIVES The objective was to evaluate t
Autor:
Guy Van den Mooter, Marc De Meulder, Tim Erkens, Patrick Sterkens, Pieter Annaert, Sandra De Jonghe, Nicolas Darville, Marjolein van Heerden, An Vynckier, An Vermeulen
Publikováno v:
Toxicologic Pathology. 44:189-210
Long-acting injectable (LAI) drug suspensions consist of drug nano-/microcrystals suspended in an aqueous vehicle and enable prolonged therapeutic drug exposure up to several months. The examination of injection site reactions (ISRs) to the intramusc
Autor:
Tim, Erkens, Ruud, Bueters, Marjolein, van Heerden, Filip, Cuyckens, Rob, Vreeken, Nick, Goeminne, Lieve, Lammens
Publikováno v:
Journal of applied toxicology : JAT. 38(10)
The intestinal barrier controls intestinal permeability, and its disruption has been associated with multiple diseases. Therefore, preclinical safety biomarkers monitoring barrier integrity are essential during the development of drugs targeting the
Publikováno v:
Journal of pharmacological and toxicological methods. 91
Introduction Multiplex immunoassays are an important tool in biomarker research during preclinical drug development. However, information regarding analytical performance of commercial multiplex assays for animal species is often limited. To be able
Autor:
Petra Vinken, L. Van den Sande, Tim Erkens, A. Kegels, Nick Goeminne, M. van Heerden, Dirk Mariën, J. Boonen
Publikováno v:
Toxicology Letters. 295:S83
Autor:
K. Van den Maagdenberg, Anneleen Stinckens, A. Van Zeveren, Luc Peelman, Nadine Buys, Tim Erkens, S. De Smet
Publikováno v:
Czech Journal of Animal Science. 55:200-208
Peroxisome proliferator-activated receptor gamma coactivator 1 alpha (PPARGC1A) is a promising candidate gene for selection on meat and carcass quality traits in the pig industry. In the pig, several SNPs have been reported in both coding and regulat
Association analyses of candidate single nucleotide polymorphisms on reproductive traits in swine1,2
Publikováno v:
Journal of Animal Science. 88:1-15
The ability to identify young females with superior reproduction would have a large econom- ic impact on commercial swine production. Previous studies have discovered SNP associated with economi- cally important traits such as litter size, growth rat
Publikováno v:
Journal of Applied Genetics. 50:361-369
Knowledge of in vivo relationship between the coactivator PPARGC1A and its target genes is very limited, especially in the pig. In this study, a real-time PCR experiment was performed on longissimus dorsi muscle (MLD) and backfat with 10 presumed PPA