Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Tim D.W. Claridge"'
Autor:
Jude E. Okokon, Idongesit C. Etuk, Paul S. Thomas, Falko P. Drijfhout, Tim D.W. Claridge, Wen-Wu Li
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 151, Iss , Pp 113153- (2022)
Solanum anomalum is a plant used ethnomedically for the treatment of diabetes. The study was aimed to validate ethnomedical claims in rat model and identify the likely antidiabetic compounds. Leaf extract (70–210 mg/kg/day) and fractions (140 mg/kg
Externí odkaz:
https://doaj.org/article/d3987371e41a463ea1607259d0c84580
Autor:
Idowu E. Fadayomi, Okiemute R. Johnson-Ajinwo, Elisabete Pires, James McCullagh, Tim D.W. Claridge, Nicholas R. Forsyth, Wen-Wu Li
Publikováno v:
Molecules, Vol 26, Iss 19, p 5933 (2021)
Objectives: The toxicity of chemotherapeutic anticancer drugs is a serious issue in clinics. Drug discovery from edible and medicinal plants represents a promising approach towards finding safer anticancer therapeutics. Justicia insularis T. Anderson
Externí odkaz:
https://doaj.org/article/266a2d3074ac464e841f62060e2f615c
Autor:
Patrick Rabe, Carla C. Walla, Noelle K. Goodyear, Jordan Welsh, Rebecca Southwart, Ian Clifton, James D.S. Linyard, Anthony Tumber, Tim D.W. Claridge, William K. Myers, Christopher J. Schofield
Publikováno v:
The Journal of biological chemistry. 298(9)
Isopenicillin N synthase (IPNS) catalyzes formation of the β-lactam and thiazolidine rings of isopenicillin N from its linear tripeptide l-δ-(α-aminoadipoyl)-l-cysteinyl-d-valine (ACV) substrate in an iron- and dioxygen (O