Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Tim D. Aumann"'
Autor:
Catherine G. Y. Ngan, Anita Quigley, Richard J. Williams, Cathal D. O’Connell, Romane Blanchard, Mitchell Boyd-Moss, Tim D. Aumann, Penny McKelvie, Gordon G. Wallace, Peter F. M. Choong, Rob M. I. Kapsa
Publikováno v:
Gels, Vol 7, Iss 4, p 171 (2021)
For decades, the study of tissue-engineered skeletal muscle has been driven by a clinical need to treat neuromuscular diseases and volumetric muscle loss. The in vitro fabrication of muscle offers the opportunity to test drug-and cell-based therapies
Externí odkaz:
https://doaj.org/article/3128f6648e3a4672be41c51ce9119b68
Publikováno v:
Stem Cell Research, Vol 23, Iss C, Pp 143-153 (2017)
The birth of new neurons, or neurogenesis, in the adult midbrain is important for progressing dopamine cell-replacement therapies for Parkinson's disease. Most studies suggest newborn cells remain undifferentiated or differentiate into glia within th
Externí odkaz:
https://doaj.org/article/3d0eebe6a50a40e5aefc146eebc4a375
Autor:
Hiroshi Takeshima, Jenny M. Gunnersen, Martina Pigoni, Stefan F. Lichtenthaler, Tim D. Aumann, Kathryn M. Munro, Amelia Nash
Publikováno v:
Cerebral cortex 30(4), 2167-2184 (2019). doi:10.1093/cercor/bhz230
Seizure-related gene 6 (Sez6), Sez6-Like (Sez6L), and Sez6-Like 2 (Sez6L2) comprise a family of homologous proteins widely expressed throughout the brain that have been linked to neurodevelopmental and psychiatric disorders. Here, we use Sez6 triple
Autor:
Ian P. Everall, Shaun Hopper, Myoung Suk Seo, Elizabeth Scarr, Gursharan Chana, Valentina Vos, Brian Dean, Tim D. Aumann
Publikováno v:
Journal of Psychiatry and Neuroscience. 43:338-346
BACKGROUND: Results of neuroimaging and postmortem studies suggest that people with schizophrenia may have lower levels of muscarinic M1 receptors (CHRM1) in the cortex, but not in the hippocampus or thalamus. Here, we use a novel immunohistochemical
Publikováno v:
Stem Cell Research, Vol 23, Iss C, Pp 143-153 (2017)
The birth of new neurons, or neurogenesis, in the adult midbrain is important for progressing dopamine cell-replacement therapies for Parkinson's disease. Most studies suggest newborn cells remain undifferentiated or differentiate into glia within th
Publikováno v:
Journal of Neurophysiology. 118:254-266
Cerebellar control of voluntary movements is achieved by the integration of external and internal feedback information to adjust and correct properly ongoing actions. In the forelimb of primates, rostral-spinocerebellar tract (RSCT) neurons are thoug
Publikováno v:
Neuroscience Letters. 648:34-40
Generation of new dopamine (DA) neurons in the adult midbrain is a controversial issue in development of better treatments for Parkinson's disease (PD). Previous research suggests Nestin-expressing neural precursor cells (NPCs) have a propensity to d
Autor:
Anupa Dey, Hamzah Baagil, Tim D. Aumann, Parisa Farzanehfar, Malcolm K. Horne, Shi Sheng Lu, Dharshani Musiienko
Publikováno v:
Stem Cell Research, Vol 19, Iss, Pp 82-93 (2017)
Whether or not neurogenesis occurs in the adult substantia nigra pars compacta (SNc) is an important question relevant for developing better treatments for the motor symptoms of Parkinson's disease (PD). Although controversial, it is generally believ
Autor:
Ruili Li, Jessica R. Riseley, Tim D. Aumann, Jeffrey R. Mann, Sarah E.M. Stephenson, Doris Tomas, Juliet M. Taylor, Paul J. Lockhart
Publikováno v:
Scientific Reports
Scientific Reports, Vol 8, Iss 1, Pp 1-11 (2018)
Scientific Reports, Vol 8, Iss 1, Pp 1-11 (2018)
Mutations in PARK2 (parkin) can result in Parkinson’s disease (PD). Parkin shares a bidirectional promoter with parkin coregulated gene (PACRG) and the transcriptional start sites are separated by only ~200 bp. Bidirectionally regulated genes have
Autor:
Tim D. Aumann, Yifat Prut
Publikováno v:
Trends in Neurosciences. 38:77-85
Coherent β-oscillations are a dominant feature of the sensorimotor system yet their function remains enigmatic. We propose that, in addition to cell intrinsic and/or local network interactions, they are supported by activity propagating recurrently