Zobrazeno 1 - 10
of 176
pro vyhledávání: '"Tim D, Hewitson"'
Publikováno v:
Kidney International Reports, Vol 5, Iss 9, Pp 1432-1447 (2020)
Introduction: Calciprotein particles (CPPs) are potentially modifiable mediators of phosphate toxicity in patients with kidney disease. We compared the effects of calcium carbonate (CC) and the non–calcium-based phosphate binder sevelamer on CPP le
Externí odkaz:
https://doaj.org/article/e094b24163e14763bd5938c8d7c26e1c
Autor:
Irene Ruderman, Tim D. Hewitson, Edward R. Smith, Stephen G. Holt, Belinda Wigg, Nigel D. Toussaint
Publikováno v:
BMC Nephrology, Vol 21, Iss 1, Pp 1-10 (2020)
Abstract Background Vascular calcification (VC) is well described in large- and medium-sized vessels in patients with chronic kidney disease (CKD), especially in those with end-stage kidney disease (ESKD) on dialysis. Medial calcification is particul
Externí odkaz:
https://doaj.org/article/3641f2a27c5e4245bcda62cae4b8fd41
Publikováno v:
BMC Nephrology, Vol 19, Iss 1, Pp 1-12 (2018)
Abstract Background The calcimimetic agent cinacalcet is effective for the management of secondary hyperparathyroidism (SHPT) in dialysis patients. Changes to reimbursement of cinacalcet in Australia provided an opportunity to assess effects of medic
Externí odkaz:
https://doaj.org/article/677d8c90f8b6425c873cc0285daae812
Autor:
Edward R. Smith, Tim D. Hewitson, Michael M. X. Cai, Parisa Aghagolzadeh, Matthias Bachtler, Andreas Pasch, Stephen G. Holt
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-17 (2017)
Abstract Calciprotein particles, nanoscale aggregates of insoluble mineral and binding proteins, have emerged as potential mediators of phosphate toxicity in patients with Chronic Kidney Disease. Although existing immunochemical methods for their det
Externí odkaz:
https://doaj.org/article/4660db06f2274211a15dd40111002799
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-14 (2017)
Abstract In kidney disease, higher circulating levels of the mineral-regulating hormone fibroblast growth factor (FGF)-23 are predictive of disease progression but direct pathogenic effects on the kidney are unknown. We sought evidence of local renal
Externí odkaz:
https://doaj.org/article/aa93e77520674b35bece2d357cb8d726
Autor:
Ursula Thiem, Tim D Hewitson, Nigel D Toussaint, Stephen G Holt, Maria C Haller, Andreas Pasch, Daniel Cejka, Edward R Smith
Publikováno v:
Nephrology Dialysis Transplantation. 38:1282-1296
Background Calciprotein particles (CPPs), colloidal mineral-protein nanoparticles, have emerged as potential mediators of phosphate toxicity in dialysis patients, with putative links to vascular calcification, endothelial dysfunction and inflammation
Autor:
Sven-Jean Tan, Melissa M Chu, Nigel D Toussaint, Michael MX Cai, Tim D Hewitson, Stephen G Holt
Publikováno v:
Journal of Circulating Biomarkers, Vol 7 (2018)
The recently discovered klotho proteins have roles in a diverse range of metabolic processes with the oldest protein, α-klotho, implicated in various cellular pathways in energy, glucose, and phosphate metabolism. Circulating soluble klotho (sKl), d
Externí odkaz:
https://doaj.org/article/61ee42cae4854e2ba3518ff0cb7fc2d2
Autor:
Edward R Smith, Tim D. Hewitson
Publikováno v:
Kidney Int
Fibroblast Growth Factor 23 (FGF23) is a bone-derived hormone that reduces kidney phosphate reabsorption and 1,25(OH)2 vitamin D synthesis via its required co-receptor alpha-Klotho. To identify novel genes that could serve as targets to control FGF23
Autor:
Edward R. Smith, Paul J. Champion de Crespigny, Fatima Vally, Tim D. Hewitson, Nigel D. Toussaint, Thomas J. Cade, Stephen G. Holt
Publikováno v:
Kidney international.
Autor:
Frank Volpato, Edward R Smith, Tim D. Hewitson, Leon J Worth, Jennifer H Yo, Paul Champion de Crespigny, Steve Christov, Connie Karschimkus, Stephen G Holt
Publikováno v:
Internal Medicine Journal
Background Measuring temperature has always been a key observation in the diagnosis of infection. No studies have examined the usefulness of measuring temperature at the wrist to detect infection. Aim We sought to determine whether a watch measuring