Extracellular histone release by renal cells after warm and cold ischemic kidney injury: Studies in an ex-vivo porcine kidney perfusion model.

Autor: Tim C van Smaalen, Danielle M H Beurskens, Jasper J H F M Kox, Rasheendra Polonia, Rein Vos, Hans Duimel, Willine J van de Wetering, Carmen López-Iglesias, Chris P Reutelingsperger, L W Ernest van Heurn, Carine J Peutz-Kootstra, Gerry A F Nicolaes

Publikováno v: PLoS ONE, Vol 18, Iss 1, p e0279944 (2023)

Extracellular histones are cytotoxic molecules involved in experimental acute kidney injury. In patients receiving a renal transplant from donors after circulatory death, who suffer from additional warm ischemia, worse graft outcome is associated wit

Externí odkaz: https://doaj.org/article/7fcf7b59f41e4937a8360811da496825

Orgaandonatie na euthanasie

Autor: Walther N.K.A. van Mook, Wim de Jongh, Ernest van Heurn, Jan Bollen, Monique van Smaalen-Croes, Annelieke Hof-van Smaalen, Tim C. van Smaalen

Publikováno v: Huisarts en wetenschap. 61:49-52

Sinds 2012 kunnen in Nederland organen en weefsels na euthanasie gedoneerd worden. Huisartsen doen het leeuwendeel van de euthanasiemeldingen; zij zijn ook bij uitstek in de positie om potentiele orgaandonoren te identificeren. Dat stelt hen geregeld

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::40b5bfebb7576bbbd2febdc9c39c9ee6
https://doi.org/10.1007/s12445-017-1014-7

Presence of Cytotoxic Extracellular Histones in Machine Perfusate of Donation After Circulatory Death Kidneys

Autor: Maarten H. L. Christiaans, Gerry A. F. Nicolaes, Tim C. van Smaalen, Danielle M. H. Beurskens, Chris P. M. Reutelingsperger, L. W. Ernest van Heurn, E. R. Pieter Hoogland, Bjorn Winkens

Publikováno v: van Smaalen, T C, Beurskens, D M H, Hoogland, E R P, Winkens, B, Christiaans, M H L, Reutelingsperger, C P, van Heurn, L W E & Nicolaes, G A F 2017, ' Presence of Cytotoxic Extracellular Histones in Machine Perfusate of Donation After Circulatory Death Kidneys ', Transplantation, vol. 101, no. 4, pp. e93-e101 . https://doi.org/10.1097/TP.0000000000001590
Transplantation, 101(4), e93-e101. Lippincott Williams and Wilkins
Transplantation, 101(4), e93-e101. LIPPINCOTT WILLIAMS & WILKINS
Transplantation

BACKGROUND: Extracellular histones are cytotoxic molecules that are related to cell stress and death. They have been shown to play a crucial role in multiple pathophysiologic processes like sepsis, inflammation, vascular dysfunction, and thrombosis.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb651e9bb3eeaffb78b8efcd8fb2eabb
https://doi.org/10.1097/tp.0000000000001590

Potential number of organ donors after euthanasia in Belgium

Autor: Rankie ten Hoopen, Walther N.K.A. van Mook, Dirk Ysebaert, Tim C. van Smaalen, Ernst van Heurn, Jan Bollen

Publikováno v: Bollen, J, Van Smaalen, T, Hoopen, R T, Van Heurn, E, Ysebaert, D & Van Mook, W 2017, ' Potential number of organ donors after euthanasia in Belgium ', JAMA-Journal of the American Medical Association, vol. 317, no. 14, pp. 1476-1477 . https://doi.org/10.1001/jama.2017.0729
JAMA : the journal of the American Medical Association
JAMA-Journal of the American Medical Association, 317(14), 1476-1477. American Medical Association
JAMA, 317(14), 1476-1477. American Medical Association

Organ donation after euthanasia involves patients whose request to undergo euthanasia has been granted and who voluntarily want to donate their organs after death. It requires patients to undergo euthanasia in the hospital, and organ donation is perf

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0de1349b5567926e9050bdf001ffc64
https://research.vumc.nl/en/publications/19e72564-1a31-4aa6-8a2b-c0a4787c5608

133rd Congress of the German Society of Surgery (DGCH). April 26-29, 2016, Berlin, Germany: Abstracts

Autor: Michael D. Menger, Peter Boor, Ľubomíra Tóthová, Julia Kalenski, Jasper J.H.F.M. Kox, Werner Kneist, Lars Fischer, Jonathan D. Hendrie, Elina Mancina, Axel Heimann, Pramod Kadaba Srinivasan, Rene Tolba, Klaus-Peter Hoffmann, Bjorn Winkens, Anas Preukschas, Felix Nickel, Christian Beckers, Christian Bleilevens, Mathias Montenarh, Christian Stock, Felix Gremse, Utz Settmacher, Tianjiao Zhang, Weiwei Wei, Jonas D Senft, Tim C. van Smaalen, Olaf Dirsch, Mamdouh Afify, Georg R. Linke, Haoshu Fang, Emmanuel Ampofo, Beat P. Müller-Stich, Benedict M. Doorschodt, Hannes Kenngott, Martin Wagner, Druckerei Stückle, Thilo Krüger, Uta Dahmen, Satz Mengensatzproduktion, Moniek G.A.M. Mestrom, Hauke Lang, Junji Iwasaki, Daniela Widmaier, Anne Porschen, Mohamed Salama, Daniel W. Kauff, Karl Friedrich Kowalewski, Matthias W. Laschke, L. W. Ernest van Heurn, N Wachter, Andrea Schenk, Dominik Gross, Pascal Paschenda, Sara Zafarnia, André Homeyer, Bodil Ohlsson

Publikováno v: European surgical research. Europaische chirurgische Forschung. Recherches chirurgicales europeennes. 57(1-2)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e909ef3e10fe4b72ea7357402b7f5b33
https://pubmed.ncbi.nlm.nih.gov/27093433