Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Tim C Roloff"'
Autor:
Florian Lienert, Fabio Mohn, Vijay K Tiwari, Tuncay Baubec, Tim C Roloff, Dimos Gaidatzis, Michael B Stadler, Dirk Schübeler
Publikováno v:
PLoS Genetics, Vol 7, Iss 6, p e1002090 (2011)
Cellular differentiation entails reprogramming of the transcriptome from a pluripotent to a unipotent fate. This process was suggested to coincide with a global increase of repressive heterochromatin, which results in a reduction of transcriptional p
Externí odkaz:
https://doaj.org/article/edf8fc02c7a84692b1783486f21c2db6
Autor:
Albana Gattelli, Ivan Nalvarte, Anne Boulay, Tim C. Roloff, Martin Schreiber, Neil Carragher, Kenneth K. Macleod, Michaela Schlederer, Susanne Lienhard, Lukas Kenner, Maria I. Torres‐Arzayus, Nancy E. Hynes
Publikováno v:
EMBO Molecular Medicine, Vol 5, Iss 9, Pp 1335-1350 (2013)
Abstract We show that elevated levels of Ret receptor are found in different sub‐types of human breast cancers and that high Ret correlates with decreased metastasis‐free survival. The role of Ret in ER+ breast cancer models was explored combinin
Externí odkaz:
https://doaj.org/article/47347e25c8bd4575a7716c866b631f36
Autor:
Tim C. Roloff, Ulrike A. Nuber
Publikováno v:
European Journal of Cell Biology. 84:123-135
Epigenetics is a term that has changed its meaning with the increasing biological knowledge on developmental processes. However, its current application to stem cell biology is often imprecise and is conceptually problematic. This article addresses t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::561f00819a255057fb030b7fa5cd926e
https://doi.org/10.1016/j.ejcb.2004.12.013
https://doi.org/10.1016/j.ejcb.2004.12.013
Autor:
Nancy E. Hynes, Stephan Duss, Dominique S. Meyer, Mohamed Bentires-Alj, Tim-C Roloff, Gwen MacDonald, Nicola Aceto
Publikováno v:
Aceto, Nicola; Duss, Stephan; MacDonald, Gwen; Meyer, Dominique S; Roloff, Tim-C; Hynes, Nancy E; et al.(2012). Co-expression of HER2 and HER3 receptor tyrosine kinases enhances invasion of breast cells via stimulation of interleukin-8 autocrine secretion. Breast Cancer Research, 14(5), R131. doi: http://dx.doi.org/10.1186/bcr3329. Retrieved from: http://www.escholarship.org/uc/item/6106p69m
Breast Cancer Research : BCR
Breast Cancer Research : BCR
Introduction The tyrosine kinase receptors HER2 and HER3 play an important role in breast cancer. The HER2/HER3 heterodimer is a critical oncogenic unit associated with reduced relapse-free and decreased overall survival. While signaling cascades dow
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf4a57e0f3c8533100f036191ad45344
http://www.escholarship.org/uc/item/6106p69m
http://www.escholarship.org/uc/item/6106p69m
Autor:
Jacky Guy, Skirmantas Kriaucionis, Tim C. Roloff, Hans-Hilger Ropers, Megan C. Holmes, Jim Selfridge, Adrian Bird, Christine Steinhoff, Ulrike A. Nuber, Bettina Lipkowitz, Ralph Schulz
Publikováno v:
Human molecular genetics. 14(15)
Rett syndrome (RTT) is a severe form of mental retardation, which is caused by spontaneous mutations in the X-linked gene MECP2. How the loss of MeCP2 function leads to RTT is currently unknown. Mice lacking the Mecp2 gene initially show normal postn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95422fc64b43c7161cb3a40337ef0f84
http://ora.ox.ac.uk/objects/uuid:9946a756-8893-4099-9320-e9cf8f9135a9
http://ora.ox.ac.uk/objects/uuid:9946a756-8893-4099-9320-e9cf8f9135a9