Výsledky vyhledávání - "Tim Babinchak"

Safety and Clinical Outcomes of an Equine-derived Heptavalent Botulinum Antitoxin Treatment for Confirmed or Suspected Botulism in the United States

Autor: Hugo Astacio, Deborah M. Anderson, Jason S. Richardson, Harpreet Sahota, Christine Hall, Tim Babinchak, Geraldine S Parrera

Publikováno v: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. 70(9)

Background Botulism is a rare, life-threatening paralytic illness. Botulism Antitoxin Heptavalent (A,B,C,D,E,F,G)-(Equine) (BAT) manufactured by Emergent BioSolutions Canada Inc is an equine-derived heptavalent botulinum antitoxin product indicated f

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42984285019a9ad3b23d4bcc62969ecd
https://pubmed.ncbi.nlm.nih.gov/31209461

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Comparative treatment-related adverse event cost burden in immune thrombocytopenic purpura

Autor: Gregg Little, J. Munakata, Tim Babinchak, P. Donga, S.P. Bilir

Aims: Real-world evidence on the safety profile and costs associated with immune thrombocytopenic purpura (ITP) treatment in adults is lacking. This study quantifies and compares adverse event (AE) crude rates and costs associated with ITP treatments

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A Phase 3, open-label, non-comparative study of tigecycline in the treatment of patients with selected serious infections due to resistant Gram-negative organisms including Enterobacter species, Acinetobacter baumannii and Klebsiella pneumoniae

Autor: Krasimir, Vasilev, Galina, Reshedko, Remus, Orasan, Miguel, Sanchez, Juri, Teras, Tim, Babinchak, Gary, Dukart, Angel, Cooper, Nathalie, Dartois, Hassan, Gandjini, Russ, Orrico, Evelyn, Ellis-Grosse, Silvestrs, Zebolds

Publikováno v: Journal of Antimicrobial Chemotherapy. 62:i29-i40

Objectives To evaluate the efficacy and safety of tigecycline in patients with selected serious infections caused by resistant Gram-negative bacteria, or failures who had received prior antimicrobial therapy or were unable to tolerate other appropria

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1de5b3fee3c48efe12119c2c3c05239e
https://doi.org/10.1093/jac/dkn249

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Methicillin-resistant Staphylococcus aureus infection epidemiology and clinical response from tigecycline soft tissue infection trials

Autor: Tim Babinchak, Michele Wible, Alvaro Quintana, Paul C. McGovern, Laura A Puzniak

Publikováno v: Diagnostic microbiology and infectious disease. 79(2)

Given increasing resistance, therapeutic options to treat MRSA soft tissue infections should be evaluated. This pooled analysis evaluated data from subjects enrolled in 6 tigecycline clinical trials with documented MRSA complicated skin and skin stru

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9680e0055c88935557a88e97e47a367e
https://pubmed.ncbi.nlm.nih.gov/24725736

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Trends in susceptibility of selected gram-negative bacilli isolated from intra-abdominal infections in North America: SMART 2005-2010

Autor: Robert E. Badal, Tim Babinchak, Samuel K. Bouchillon, Meredith Hackel, Stephen Hawser, Sibylle H. Lob, Daryl J. Hoban

Publikováno v: Diagnostic microbiology and infectious disease. 76(3)

This report summarizes data from the Study for Monitoring Antimicrobial Resistance Trends 2005-2010 to identify trends in susceptibility from intra-abdominal infections in North America. Escherichia coli and Klebsiella pneumoniae were the most freque

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01cf30e8c9463a6a3fe7a98d808229cd
https://pubmed.ncbi.nlm.nih.gov/23541118

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Efficacy of tigecycline versus ceftriaxone plus metronidazole for the treatment of complicated intra-abdominal infections: results from a randomized, controlled trial

Autor: Heidi Leister-Tebbe, Ronald Pedersen, Brian Warren, Tim Babinchak, Niels Qvist, Edward T Zito, Paul C. McGovern

Publikováno v: Qvist, N, Warren, B, Leister-Tebbe, H, Zito, E T, Pedersen, R, McGovern, P C & Babinchak, T 2012, ' Efficacy of tigecycline versus ceftriaxone plus metronidazole for the treatment of complicated intra-abdominal infections : results from a randomized, controlled trial ', Surgical Infections, vol. 13, no. 2, pp. 102-9 . https://doi.org/10.1089/sur.2011.048

This randomized, open-label, multi-center trial compared tigecycline (TGC), a broad-spectrum glycylcycline, with ceftriaxone-metronidazole (CTX/MET) for the treatment of complicated intra-abdominal infections (cIAI).Eligible subjects were randomized

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4762ff3df5d1415d7ba911a1759f0e55
https://pubmed.ncbi.nlm.nih.gov/22439781

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Rising incidence of Staphylococcus aureus with reduced susceptibility to vancomycin and susceptibility to antibiotics: a global analysis 2004-2009

Autor: Tim Babinchak, Michael J. Dowzicky, Stephen Hawser, Daryl J. Hoban, Samuel K. Bouchillon

Publikováno v: International journal of antimicrobial agents. 37(3)

During 2004-2009, 20004 isolates of Staphylococcus aureus were collected from the Tigecycline Evaluation and Surveillance Trial (T.E.S.T.). Of these isolates, 8249 (41.2%) were meticillin-resistant S. aureus (MRSA) and 11755 (58.8%) were meticillin-s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::427fad89c5b418cfb28031d70325f2a0
https://pubmed.ncbi.nlm.nih.gov/21239146

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COLONIZATION OF ORTHOPAEDIC TRAUMA IMPLANTS IN PATIENTS WITHOUT EVIDENCE OF INFECTION

Autor: Brian Divelbiss, Maureen Murphy, Spencer L. Butterfield, Tim Babinchak, Barry L. Riemer

Publikováno v: The Journal of Trauma: Injury, Infection, and Critical Care. 45:1111

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f214b19e05e55512d25b722742b298c8
https://doi.org/10.1097/00005373-199812000-00048

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