Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Tim B. Koenen"'
Autor:
Mihai G. Netea, Rinke Stienstra, Edwin J.P. van Asseldonk, Cees J. Tack, Tim B. Koenen, Leo A. B. Joosten
Publikováno v:
Journal of Clinical Endocrinology and Metabolism, 96, 7, pp. 2119-26
Journal of Clinical Endocrinology and Metabolism, 96, 2119-26
Journal of Clinical Endocrinology and Metabolism, 96, 2119-26
Contains fulltext : 98491.pdf (Publisher’s version ) (Open Access) CONTEXT: Obesity induces low-grade inflammation that may promote the development of insulin resistance. IL-1 is one of the key inflammatory factors. OBJECTIVE: The objective of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81ca187e2181e4917c07735d0445a46e
https://doi.org/10.1210/jc.2010-2992
https://doi.org/10.1210/jc.2010-2992
Autor:
Anton F. H. Stalenhoef, Tim B. Koenen, Heidi Lemmers, Martin den Heijer, Suzanne Holewijn, Jacqueline de Graaf, Lambertus J.H. van Tits
Publikováno v:
Biochemical and Biophysical Research Communications, 376, 1, pp. 164-8
Biochemical and Biophysical Research Communications, 376, 164-8
Biochemical and Biophysical Research Communications, 376, 164-8
Contains fulltext : 69561tits.pdf (Publisher’s version ) (Closed access) Adiponectin is secreted from adipocytes in different multimers, of which the high molecular weight (HMW) form is supposed to mediate favorable metabolic and anti-atherogenic e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ac01d6133c3fe946b07e752b607ad2b
https://doi.org/10.1016/j.bbrc.2008.08.111
https://doi.org/10.1016/j.bbrc.2008.08.111
Autor:
Tim B. Koenen, Han Gerrits, Dorette S. van Ingen Schenau, Laura S. Hermens, Nicole E. C. Bakker, Ad J.M. van Disseldorp, Jan A. Gossen, Magda A.M. Krajnc-Franken, Ankie M. Strik
Publikováno v:
genesis. 46:235-245
CXCR7 is a G-protein coupled receptor that was recently deorphanized and shown to have SDF1 and I-TAC as high affinity ligands. Here we describe the characterization of CXCR7-deficient mice that were generated to further investigate the function of t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cbc5e4426850ae327203698cbfe5850f
https://doi.org/10.1002/dvg.20387
https://doi.org/10.1002/dvg.20387
Autor:
H.J. Jansen, Mihai G. Netea, Tim B. Koenen, Cees J. Tack, Rinke Stienstra, P. van Essen, Leo A. B. Joosten
Publikováno v:
Endocrinology, 153(12), 5866-5874
Endocrinology 153 (2012) 12
Endocrinology, 153, 5866-74
Endocrinology, 153, 12, pp. 5866-74
Endocrinology 153 (2012) 12
Endocrinology, 153, 5866-74
Endocrinology, 153, 12, pp. 5866-74
Autophagy, an evolutionary conserved process aimed at recycling damaged organelles and protein aggregates in the cell, also modulates proinflammatory cytokine production in peripheral blood mononuclear cells. Because adipose tissue inflammation accom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39ba9612181bcea52adacdde9003bc7b
https://research.wur.nl/en/publications/autophagy-activity-is-up-regulated-in-adipose-tissue-of-obese-ind
https://research.wur.nl/en/publications/autophagy-activity-is-up-regulated-in-adipose-tissue-of-obese-ind
Autor:
Rinke Stienstra, Anton F. H. Stalenhoef, Anneke Hijmans, Jacqueline de Graaf, J.A. van der Vliet, Lambertus J.H. van Tits, Cees J. Tack, Leo A. B. Joosten, Jeroen F. van Velzen, Mihai G. Netea, Jillis A. Pol, Tim B. Koenen
Publikováno v:
Endocrinology 152 (2011) 10
Endocrinology, 152, 10, pp. 3769-78
Endocrinology, 152, 3769-78
Endocrinology, 152(10), 3769-3778
Endocrinology, 152, 10, pp. 3769-78
Endocrinology, 152, 3769-78
Endocrinology, 152(10), 3769-3778
Contains fulltext : 97441.pdf (Publisher’s version ) (Open Access) The immune competent abdominal adipose tissue, either stored viscerally [visceral adipose tissue (VAT)] or sc [sc adipose tissue (SAT)], has been identified as a source of IL-1beta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee437cb751539e005fbeae6e9d1f7e86
https://hdl.handle.net/https://repository.ubn.ru.nl/handle/2066/97441
https://hdl.handle.net/https://repository.ubn.ru.nl/handle/2066/97441
Autor:
Jacqueline de Graaf, Tim B. Koenen, Lambertus J.H. van Tits, Leo A. B. Joosten, Mihai G. Netea, Rinke Stienstra, Cees J. Tack, Anton F. H. Stalenhoef
Publikováno v:
Diabetes
Diabetes, 60, 517-24
Diabetes, 60, 2, pp. 517-24
Diabetes, 60, 517-24
Diabetes, 60, 2, pp. 517-24
OBJECTIVE Obesity is characterized by elevated levels of proinflammatory cytokines, including interleukin (IL)-1β, that contribute to the development of insulin resistance. In this study, we set out to investigate whether hyperglycemia drives IL-1β
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e20dc69a33d85b0a17276a495e0bff9
https://doi.org/10.2337/db10-0266
https://doi.org/10.2337/db10-0266
Autor:
Edwin J.P. van Asseldonk, Tim B. Koenen, Leo A. B. Joosten, Cees J. Tack, Mihai G. Netea, Lambertus J.H. van Tits, Rinke Stienstra
Publikováno v:
Obesity, 18, 2234-6
Obesity, 18, 11, pp. 2234-6
Obesity, 18, 11, pp. 2234-6
Contains fulltext : 88907.pdf (Publisher’s version ) (Closed access) Obesity is characterized by chronic low-grade inflammation originating from expanding adipose tissue. In the present study, we examined the adipogenic expression levels of IL-1F6
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73cbc0860ada3b0831fbc1d60c12725f
http://hdl.handle.net/2066/88907
http://hdl.handle.net/2066/88907
Autor:
Tim B. Koenen, Peter J. Voshol, Sander Kersten, Janna A. van Diepen, Anneke Hijmans, Giamilla Fantuzzi, Bart Jan Kullberg, Nico van Rooijen, Berry van Tits, Cees J. Tack, Mihai G. Netea, Martin Wabitsch, Michael Müller, Sjoerd A.A. van den Berg, Jos W. M. van der Meer, Rinke Stienstra, Leo A. B. Joosten, Wim B. van den Berg, Patrick C.N. Rensen, Thirumala D. Kanneganti
Publikováno v:
Cell Metabolism, 12(6), 593-605
Cell Metabolism 12 (2010) 6
Cell Metabolism, 12, 6, pp. 593-605
Cell Metabolism, 12, 593-605
Cell Metabolism 12 (2010) 6
Cell Metabolism, 12, 6, pp. 593-605
Cell Metabolism, 12, 593-605
Contains fulltext : 87798.pdf (Publisher’s version ) (Closed access) Obesity-induced inflammation originating from expanding adipose tissue interferes with insulin sensitivity. Important metabolic effects have been recently attributed to IL-1beta a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0d91f90f308fe4662de1063f072ec20
https://research.wur.nl/en/publications/the-inflammasome-mediated-caspase-1-activation-controls-adipocyte
https://research.wur.nl/en/publications/the-inflammasome-mediated-caspase-1-activation-controls-adipocyte
Autor:
Henrique J. Jansen, Edwin J.P. van Asseldonk, Tim B. Koenen, Rinke Stienstra, M.G. Netea, Cees J. Tack
Publikováno v:
Nederlands Tijdschrift voor Diabetologie. 9:142-143
Obesity is associated with inflammation at the level of the fat tissue, but the initiating mechanisms are unclear. Toll like receptors (TLRs) are at the frontline of innate immunity. TLRs sense specific exogenous and endogenous ligands. TLR3 typicall
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5748093ccfed8f5690f6928bd611de20
https://doi.org/10.1007/s12467-011-0101-9
https://doi.org/10.1007/s12467-011-0101-9
Autor:
Janna A. van Diepen, Cees J. Tack, Dov B. Ballak, Rinke Stienstra, Leo A. B. Joosten, Tim B. Koenen, Edwin J.P. van Asseldonk, Mihai G. Netea, H.J. Jansen
Publikováno v:
Nederlands Tijdschrift voor Diabetologie. 11:133-133
Obesity is associated with systemic, chronic low-grade inflammation arising from adipose tissue, leading to the development of insulin resistance and eventually type 2 diabetes. The infiltration of macrophages in adipose tissue is pivotal in the inst
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c703d36d7b805f8f0119692c10a66462
https://doi.org/10.1007/s12467-013-0064-0
https://doi.org/10.1007/s12467-013-0064-0