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pro vyhledávání: '"Tim Morley"'
Autor:
Peter Dogterom, Camille Omar Farouk Kamlin, Tim Morley, Naseem Amin, Brinley Jackson, Karl Heinz Weiss, Catherine Thompson, Yi-Jin Chiou
Publikováno v:
European Journal of Drug Metabolism and Pharmacokinetics. 46:665-675
Wilson disease (WD) is an autosomal recessive inherited disorder of copper metabolism. Chelation of excessive copper is recommended but data on the pharmacokinetics of trientine are limited. The aim of this study was to compare the pharmacokinetics o
Autor:
Tim Morley, Christian Ward-Deitrich, M. Estela del Castillo Busto, Heidi Goenaga-Infante, Susana Cuello-Nuñez
Publikováno v:
Analytical and Bioanalytical Chemistry. 414:561-573
Exchangeable copper (CuEXC), mainly comprised copper (Cu) bound to albumin, has been proposed as a specific marker of Cu overload in Wilson's disease (WD). To the author's knowledge, there are no methods capable of determining reliably CuEXC to meet
Publikováno v:
Revue Neurologique. 177:S51-S52
Introduction La maladie de Wilson est liee a une accumulation de cuivre dans l’organisme necessitant un traitement a vie. Les sels de trientine, chelateurs du cuivre, sont disponibles en 2nde intention. Objectifs Comparer le profil pharmacocinetiqu
Publikováno v:
Journal of Hepatology. 73:S546-S547
Autor:
Joshua Rhea, Tim Morley, Zhicai Yang, Michael Guaciaro, Ursula Mocek, Ricardo Reategui, Bruce F Molino, Xiaomin Jin
Publikováno v:
Organic letters. 13(20)
A total synthesis of both diastereomers of the originally proposed structure for streptophenazine A (1) has been achieved. However, both synthetic compounds are different from the natural product. Re-examination of NMR data reported for streptophenaz
Autor:
Tim Morley
Publikováno v:
Spinal Cord. 38:774-774
Autor:
Zhicai Yang, Xiaomin Jin, Michael Guaciaro, Bruce F. Molino, Ursula Mocek, Ricardo Reategui, Joshua Rhea, Tim Morley
Publikováno v:
Organic Letters; Oct2011, Vol. 13 Issue 20, p5436-5439, 4p