Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Tim, Michelberger"'
Autor:
Agata N. Makar, Alina Boraman, Peter Mosen, Joanne E. Simpson, Jair Marques, Tim Michelberger, Stuart Aitken, Ann P. Wheeler, Dominic Winter, Alex von Kriegsheim, Noor Gammoh
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Autophagy is a finely orchestrated process required for the lysosomal degradation of cytosolic components. The final degradation step is essential for clearing autophagic cargo and recycling macromolecules. Using a CRISPR/Cas9-based screen,
Externí odkaz:
https://doaj.org/article/6883251db50c4cf790616ebe8bd9529f
Autor:
Gabriele S. Kaminski Schierle, Janine Kirstein, Tanmoyita Nayak, Tim Michelberger, Fan Liu, Sara Maria Ayala Mariscal, Dmytro Puchkov, Christian Gallrein, Manuel Iburg, Alen Koçak
Publikováno v:
Progress in neurobiology. 198
Protein misfolding and aggregation are hallmarks of neurodegenerative diseases such as Alzheimer’s disease (AD). In AD, the accumulation and aggregation of tau and the amyloid-beta peptide Aβ1−42 precedes the onset of AD symptoms. Modelling the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2277f77e88e6c7f2710f989832322bc3
https://pubmed.ncbi.nlm.nih.gov/32926945
https://pubmed.ncbi.nlm.nih.gov/32926945
Publikováno v:
The EMBO Journal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=r3c4b2081b22::8e6b035d6da8bf924abbfe4f950633a1
Autor:
Leo J, Dudley, Ainara G, Cabodevilla, Agata N, Makar, Martin, Sztacho, Tim, Michelberger, Joseph A, Marsh, Douglas R, Houston, Sascha, Martens, Xuejun, Jiang, Noor, Gammoh
Publikováno v:
The EMBO Journal
Membrane targeting of autophagy‐related complexes is an important step that regulates their activities and prevents their aberrant engagement on non‐autophagic membranes. ATG16L1 is a core autophagy protein implicated at distinct phases of autoph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3c6e710a6544b938811cd065b813646f
https://pubmed.ncbi.nlm.nih.gov/30936093
https://pubmed.ncbi.nlm.nih.gov/30936093