Zobrazeno 1 - 10
of 197
pro vyhledávání: '"Tim, Lahm"'
Publikováno v:
BMJ Medicine, Vol 2, Iss 1 (2023)
Pulmonary hypertension is a progressive and often fatal cardiopulmonary condition characterised by increased pulmonary arterial pressure, structural changes in the pulmonary circulation, and the formation of vaso-occlusive lesions. These changes lead
Externí odkaz:
https://doaj.org/article/4b23ca39c071452db571e0fb6d5778dd
Autor:
Mariana DuPont, Savanna Lambert, Antonio Rodriguez‐Martin, Okaeri Hernandez, Mark Lagatuz, Taygan Yilmaz, Andrew Foderaro, Grayson L. Baird, Patricia Parsons‐Wingerter, Tim Lahm, Maria B. Grant, Corey E. Ventetuolo
Publikováno v:
Pulmonary Circulation, Vol 12, Iss 1, Pp n/a-n/a (2022)
Abstract Pulmonary arterial hypertension (PAH) is classically considered an isolated small vessel vasculopathy of the lungs with peripheral pulmonary vascular obliteration. Systemic manifestations of PAH are increasingly acknowledged, but data remain
Externí odkaz:
https://doaj.org/article/692067a621a946f5ad2018c46d95fa04
Autor:
R. Dale Brown, Kendall S. Hunter, Min Li, Maria G. Frid, Julie Harral, Greta M. Krafsur, Timothy N. Holt, Jason Williams, Hui Zhang, Suzette R. Riddle, Michael G. Edwards, Sushil Kumar, Cheng-Jun Hu, Brian B. Graham, Lori A. Walker, Franklyn B. Garry, Peter M. Buttrick, Tim Lahm, Vitaly O. Kheyfets, Kirk C. Hansen, Kurt R. Stenmark
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 324:H804-H820
Using a large animal model and employing a comprehensive approach integrating hemodynamic, transcriptomic, proteomic, and immunohistochemical analyses, we examined the early (2 wk) effects of severe PH on the RV. We observed that RV remodeling during
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e426dd05eb030a8846d9667ad5f8d584
https://doi.org/10.1152/ajpheart.00614.2022
https://doi.org/10.1152/ajpheart.00614.2022
Autor:
Mariana DuPont, John Hunsicker, Simona Shirley, William Warriner, Annabelle Rowland, Reddhyia Taylor, Michael DuPont, Mark Lagatuz, Taygan Yilmaz, Andrew Foderaro, Tim Lahm, Corey E. Ventetuolo, Maria B. Grant
Publikováno v:
Life, Vol 12, Iss 12, p 1985 (2022)
(1) Background: Retinal vascular imaging plays an essential role in diagnosing and managing chronic diseases such as diabetic retinopathy, sickle cell retinopathy, and systemic hypertension. Previously, we have shown that individuals with pulmonary a
Externí odkaz:
https://doaj.org/article/ad79ee7e03c443a4abdd10b60f8cae1f
SOX17 Deficiency Mediates Pulmonary Hypertension: At the Crossroads of Sex, Metabolism, and Genetics
Autor:
Shreya Sangam, Xutong Sun, Tae-Hwi Schwantes-An, Manivannan Yegambaram, Qing Lu, Yinan Shi, Todd Cook, Amanda Fisher, Andrea L. Frump, Anna Coleman, Yanan Sun, Shuxin Liang, Howard Crawford, Katie A. Lutz, Avinash D. Maun, Michael W. Pauciulo, Jason H. Karnes, Ketul R. Chaudhary, Duncan J. Stewart, Paul R. Langlais, Mohit Jain, Mona Alotaibi, Tim Lahm, Yan Jin, Haiwei Gu, Haiyang Tang, William C. Nichols, Stephen M. Black, Ankit A. Desai
Publikováno v:
American Journal of Respiratory and Critical Care Medicine. 207:1055-1069
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1ee02d45241d5750f5085b868b68ea01
https://doi.org/10.1164/rccm.202203-0450oc
https://doi.org/10.1164/rccm.202203-0450oc
Autor:
Andrea L. Frump, Bakhtiyor Yakubov, Avram Walts, Amanda Fisher, Todd Cook, Naomi C. Chesler, Tim Lahm
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology. 68:341-344
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::577e8f3f2ce3c0f9acdacad79500437c
https://doi.org/10.1165/rcmb.2022-0224le
https://doi.org/10.1165/rcmb.2022-0224le
Autor:
Michael C Honigberg, Aniruddh P Patel, Tim Lahm, Malissa J Wood, Jennifer E Ho, Puja Kohli, Pradeep Natarajan
Publikováno v:
PLoS ONE, Vol 16, Iss 3, p e0247398 (2021)
BackgroundSeveral forms of pulmonary hypertension (PH) disproportionately affect women. Animal and human studies suggest that estradiol exerts mixed effects on the pulmonary vasculature. Whether premature menopause represents a risk factor for PH is
Externí odkaz:
https://doaj.org/article/dd1c31530f7443ca91b46ef7fa79ef2b
Publikováno v:
Pulmonary Circulation, Vol 10 (2020)
Immune checkpoint inhibitors successfully treat various malignancies by inducing an immune response to tumor cells. However, their use has been associated with a variety of autoimmune disorders, such as diabetes, hepatitis, and pneumonitis. Pulmonary
Externí odkaz:
https://doaj.org/article/6cea22bdf2e94802a6a6d9ed76418d87
Autor:
Gary Marshall Long, Ashley D. Troutman, Derrick A. Gray, Amanda J. Fisher, Tim Lahm, Andrew R. Coggan, Mary Beth Brown
Publikováno v:
American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. 323:R561-R570
Pulmonary arterial hypertension (PAH) is characterized by exercise intolerance. Muscle blood flow may be reduced during exercise in PAH; however, this has not been directly measured. Therefore, we investigated blood flow during exercise in a rat mode
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::164b803d4db4ec3a8c07d8e080438c85
https://doi.org/10.1152/ajpregu.00327.2021
https://doi.org/10.1152/ajpregu.00327.2021
Autor:
Derek Strassheim, Timothy Sullivan, David C. Irwin, Evgenia Gerasimovskaya, Tim Lahm, Dwight J. Klemm, Edward C. Dempsey, Kurt R. Stenmark, Vijaya Karoor
Publikováno v:
Cells, Vol 10, Iss 12, p 3347 (2021)
G protein-coupled receptors (GPCRs) have originally been described as a family of receptors activated by hormones, neurotransmitters, and other mediators. However, in recent years GPCRs have shown to bind endogenous metabolites, which serve functions
Externí odkaz:
https://doaj.org/article/4cf5369074f34c7fa9694ff0f0312039