Zobrazeno 1 - 10
of 241
pro vyhledávání: '"Tim, Harrison"'
Publikováno v:
IET Intelligent Transport Systems, Vol 18, Iss 10, Pp 1931-1942 (2024)
Abstract The UK rail network is subject to costly disruption due to the operational effects of adhesion variation between the wheel and rail. Causes of this are often environmental introduction of contaminants that require a wide‐scale approach to
Externí odkaz:
https://doaj.org/article/4f8bf2160035488cbe2a6b6f4bbb40a9
Publikováno v:
Railway Engineering Science, Vol 32, Iss 2, Pp 162-176 (2024)
Abstract The main contribution of this paper is the development and demonstration of a novel methodology that can be followed to develop a simulation twin of a railway track switch system to test the functionality in a digital environment. This is im
Externí odkaz:
https://doaj.org/article/b0945cafa4d843388bd0ce318d218584
Autor:
Pepa Bruce, Lee Hatter, Claire Houghton, Ciléin Kearns, Mark Holliday, Augustus J. Anderson, Allie Eathorne, John Martindale, Alex Semprini, Mark Weatherall, Ian Pavord, Tim Harrison, Alberto Papi, Rob Horne, Richard Beasley
Publikováno v:
ERJ Open Research, Vol 9, Iss 5 (2023)
Background The stepwise approach to long-term asthma management, which traditionally incorporates short-acting β2-agonist reliever therapy, has been a core feature of asthma guidelines for over 30 years. There have been no studies, however, directly
Externí odkaz:
https://doaj.org/article/67199b054e7140a283abd401565a550f
Autor:
Richard Beasley, Irene Braithwaite, Ian Pavord, Mark Holliday, Tim Harrison, Helen Reddel, Juliet Foster
Publikováno v:
BMJ Open, Vol 12, Iss 1 (2022)
Externí odkaz:
https://doaj.org/article/bd35790498424be29d721bb957fa80ae
Autor:
Alexandra Jauhiainen, Lieke E.J.M. Scheepers, Anne L. Fuhlbrigge, Tim Harrison, James Zangrilli, Esther Garcia Gil, Per Gustafson, Malin Fagerås, Carla A. Da Silva
Publikováno v:
ERJ Open Research, Vol 6, Iss 4 (2020)
Background CompEx Asthma, a novel composite end-point combining severe exacerbations (SevEx) with asthma-worsening events, was recently developed. Further characterisation of CompEx Asthma is needed to illustrate the applicability of this end-point.
Externí odkaz:
https://doaj.org/article/a93aa734816d49f7a9fba264c3903b98
Autor:
Tim Harrison, Ian D. Pavord, James D. Chalmers, Glenn Whelan, Malin Fagerås, Annika Rutgersson, Laura Belton, Shahid Siddiqui, Per Gustafson
Publikováno v:
ERJ Open Research, Vol 6, Iss 2 (2020)
Asthma is a chronic inflammatory airway disease. Increase in airway inflammation is hypothesised to contribute to worsening of asthma symptoms and deterioration in lung function, resulting in the use of reliever medication. Short-acting β2-agonists
Externí odkaz:
https://doaj.org/article/20f211cb9ac4460b951a67b66f2a5c1c
Autor:
Judith E Pekelharing, Francis Gatluak, Tim Harrison, Fernando Maldonado, M Ruby Siddiqui, Koert Ritmeijer
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 14, Iss 1, p e0007992 (2020)
INTRODUCTION:Visceral leishmaniasis (VL) is endemic in South Sudan, where outbreaks occur frequently. Because of changes in the immune system during pregnancy, pregnant women are considered particularly vulnerable for developing complications of VL d
Externí odkaz:
https://doaj.org/article/cafe50bad0c34c41b34735311fae8b0f
Autor:
Catherine E. Hanratty, John G. Matthews, Joseph R. Arron, David F. Choy, Ian D. Pavord, P. Bradding, Christopher E. Brightling, Rekha Chaudhuri, Douglas C. Cowan, Ratko Djukanovic, Nicola Gallagher, Stephen J. Fowler, Tim C. Hardman, Tim Harrison, Cécile T. Holweg, Peter H. Howarth, James Lordan, Adel H. Mansur, Andrew Menzies-Gow, Sofia Mosesova, Robert M. Niven, Douglas S. Robinson, Dominick E. Shaw, Samantha Walker, Ashley Woodcock, Liam G. Heaney, on behalf of the RASP-UK (Refractory Asthma Stratification Programme) Consortium
Publikováno v:
Trials, Vol 19, Iss 1, Pp 1-13 (2018)
Abstract Background Patients with difficult-to-control asthma consume 50–60% of healthcare costs attributed to asthma and cost approximately five-times more than patients with mild stable disease. Recent evidence demonstrates that not all patients
Externí odkaz:
https://doaj.org/article/8b2b5c94718a45699e6b6b269b64f460
Autor:
Tricia McKeever, Kevin Mortimer, Lucy Bradshaw, Rebecca Haydock, Ian Pavord, Bernard Higgins, Samantha Walker, Andrew Wilson, David Price, Mike Thomas, Graham Devereux, Christopher Brightling, Charlotte Renwick, Steve Parrott, Eleanor Mitchell, Lelia Duley, Tim Harrison
Publikováno v:
Health Technology Assessment, Vol 22, Iss 70 (2018)
Background: Asthma exacerbations affect the quality of life of patients with asthma and have a major effect on the overall costs of asthma care. An asthma self-management plan that advises the temporary quadrupling of inhaled corticosteroid dose may
Externí odkaz:
https://doaj.org/article/97ff7a927ea44209b5097aa60be450df
Publikováno v:
Applied Sciences, Vol 11, Iss 2, p 702 (2021)
This paper focuses on modelling, control, realisation and performance analysis of a full-scale demonstrator for a novel railway track switch. For over a century, railway track switches (or points) have been allowing trains to safely change between ro
Externí odkaz:
https://doaj.org/article/64c1a77f5c57466b94df56aeb07980e9