Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Tim, Crea"'
Autor:
Kevin Ronald Condroski, Matt Hickman, Wei Liu, Laurie LeBrun, Gilles Carmel, Joshua Hansen, Gang Lu, Afshin Mahmoudi, Frans Baculi, Correa Matthew D, Tim Crea, Hon-Wah Man, George W. Muller, Chin-Chun Lu, Alexander L. Ruchelman, Fan Vocanson, Weihong Zhang
Publikováno v:
Journal of Medicinal Chemistry. 61:492-503
We previously disclosed the identification of cereblon modulator 3 (CC-885), with potent antitumor activity mediated through the degradation of GSPT1. We describe herein the structure–activity relationships for analogs of 3 with exploration of the
Autor:
Joshua D, Hansen, Kevin, Condroski, Matthew, Correa, George, Muller, Hon-Wah, Man, Alexander, Ruchelman, Weihong, Zhang, Fan, Vocanson, Tim, Crea, Wei, Liu, Gang, Lu, Frans, Baculi, Laurie, LeBrun, Afshin, Mahmoudi, Gilles, Carmel, Matt, Hickman, Chin-Chun, Lu
Publikováno v:
Journal of medicinal chemistry. 61(2)
We previously disclosed the identification of cereblon modulator 3 (CC-885), with potent antitumor activity mediated through the degradation of GSPT1. We describe herein the structure-activity relationships for analogs of 3 with exploration of the st