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Phosphatidylinositol binding of Saccharomyces cerevisiae Pdr16p represents an essential feature of this lipid transfer protein to provide protection against azole antifungals

Autor: Roman, Holič, Zuzana, Simová, Tim, Ashlin, Vladimír, Pevala, Katarína, Poloncová, Dana, Tahotná, Eva, Kutejová, Shamshad, Cockcroft, Peter, Griač

Publikováno v: Biochimica et Biophysica Acta

Pdr16p is considered a factor of clinical azole resistance in fungal pathogens. The most distinct phenotype of yeast cells lacking Pdr16p is their increased susceptibility to azole and morpholine antifungals. Pdr16p (also known as Sfh3p) of Saccharom

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::596ff62f6511c69f123c2d85df34ef19
https://pubmed.ncbi.nlm.nih.gov/25066473

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