Zobrazeno 1 - 10
of 201
pro vyhledávání: '"Tilser I"'
Publikováno v:
In Experimental and Toxicologic Pathology 2001 53(1):71-76
Proteasome inhibitors are novel therapeutic agents for the treatment of cancer and other severe disorders. One of the possible side effects is influencing the metabolism of proteins. The aim of our study was to evaluate the influence of three proteas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::f59397d5d4abec0f54ec09cbc77a65a0
https://ora.ox.ac.uk/objects/uuid:9011eb82-73ea-4649-a35d-2557601a9ff2
https://ora.ox.ac.uk/objects/uuid:9011eb82-73ea-4649-a35d-2557601a9ff2
Autor:
Tilser I, Miroslav Kovarik, Ludek Sispera, Milan Holecek, Oleg V. Larionov, A. De Meijere, Tomas Muthny
Publikováno v:
ResearcherID
The proteasome inhibitors are used as research tools to study of the ATP-dependent ubiquitin-proteasome system. Some of them are at present undergoing clinical trials to be used as therapeutic agents for cancer or inflammation. These diseases are oft
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d809e015b45f451fe87f253d29539440
https://doi.org/10.1007/bf03179064
https://doi.org/10.1007/bf03179064
Publikováno v:
International Journal of Experimental Pathology. 89:64-71
The aim of our study was to evaluate the differences in protein and amino acid metabolism after subcutaneous turpentine administration in the soleus muscle (SOL), predominantly composed of red fibres, and the extensor digitorum longus muscle (EDL) co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::61e1390a964110d9a36a040c635285bd
https://doi.org/10.1111/j.1365-2613.2007.00553.x
https://doi.org/10.1111/j.1365-2613.2007.00553.x
Publikováno v:
European Journal of Clinical Pharmacology. 61:417-423
To analyse whether there exists a socio-economic gradient in utilisation of cardiovascular drugs at the district level in the Czech Republic.The aggregated data on drug utilisation during the period 1997-2000, expressed in defined daily doses per 100
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a42f666400cd2bb783e472af6da4471
https://doi.org/10.1007/s00228-005-0929-2
https://doi.org/10.1007/s00228-005-0929-2
Publikováno v:
ResearcherID
Proteasome inhibitors are novel potential drugs for therapy of many diseases, and their effects are not fully understood. We investigated direct effects of peptide vinylsulfone inhibitor AdaAhx3L3VS on protein and amino acids metabolism in rat skelet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::baa8de3f2c622fbad43569b2c9da1bb0
https://doi.org/10.33549/physiolres.930653
https://doi.org/10.33549/physiolres.930653
Publikováno v:
International Journal of Experimental Pathology. 85:365-371
The ubiquitin–proteasome system (UPS) is a proteolytic system that is localized in cytosol and nucleus and requires ATP and mostly also the cofactor ubiquitin for proteolysis. Proteins to be degraded by UPS are tagged by polyubiquitin chain in a pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e9a6d1eeb69da0c2a2153ac59ed26eaf
https://doi.org/10.1111/j.0959-9673.2004.00405.x
https://doi.org/10.1111/j.0959-9673.2004.00405.x
Publikováno v:
Amino Acids. 10:229-241
We studied the plasma amino acid profiles in four models of hepatic injury in rats. In partially hepatectomized rats (65% of liver was removed) we observed significant increase of aromatic amino acids (AAA; i.e. tyrosine and phenylalanine), taurine,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68ca55c0cb4cc1d22a7739b2d6ab68d9
https://doi.org/10.1007/bf00807325
https://doi.org/10.1007/bf00807325
Publikováno v:
Scopus-Elsevier
The aim of this study was to evaluate the effect of chronic uremia induced by 5/6 nephrectomy (5/6NX) on changes in protein and branched-chain amino acid (BCAA; valine, leucine and isoleucine) metabolism. The control group consisted of sham operated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6620f2481425245dbf5fe8ac7a09a6b3
https://pubmed.ncbi.nlm.nih.gov/11370737
https://pubmed.ncbi.nlm.nih.gov/11370737
Publikováno v:
Journal of Physiology & Biochemistry; Jun2009, Vol. 65 Issue 2, p137-146, 10p