Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Tilo Schwientek"'
Autor:
Isabelle Breloy, Tilo Schwientek, Deborah Althoff, Marvin Holz, Tim Koppen, Angelika Krupa, Franz-Georg Hanisch
Publikováno v:
Biomolecules, Vol 6, Iss 1, p 8 (2016)
The Drosophila melanogaster glucuronyltransferases dGlcAT-S and dGlcAT-P were reported to be expressed ubiquitously and results of in vitro activity assays indicate a functional redundancy. We analyzed both transferases in vivo and in vitro and could
Externí odkaz:
https://doaj.org/article/a154136886384475995adf01eaeff62e
Autor:
Usha Menon, Joy Burchell, Aaron S. Nudelman, P. Trinder, R Desai, Hans H. Wandall, Joyce Taylor-Papadimitriou, D. Bueti, Liliana Silva, Celso A. Reis, Anne Dawnay, Hugo Osório, Johannes W. Pedersen, Leonor David, Ulla Mandel, Rachel Hallett, Ian S. Fentiman, Ola Blixt, Henrik Clausen, Alexander Gammerman, Aleksandra Gentry-Maharaj, Ian Jacobs, Rosalind Graham, Bruce Acres, Tilo Schwientek, Jeremy Ford, D. Allen, Evangelia-Ourania Fourkala, Brian Burford, Michael A Hollingsworth
Publikováno v:
British Journal of Cancer; Vol 108
British Journal of Cancer
British Journal of Cancer
Background: Autoantibodies have been detected in sera before diagnosis of cancer leading to interest in their potential as screening/early detection biomarkers. As we have found autoantibodies to MUC1 glycopeptides to be elevated in early-stage breas
Autor:
Eric P. Bennett, Ola Blixt, Henrik Clausen, Wu Yin, Steven B. Levery, Katrine T. Schjoldager, Malene Bech Vester-Christensen, Tilo Schwientek
Publikováno v:
Journal of Biological Chemistry. 285:36293-36303
The angiopoietin-like protein 3 (ANGPTL3) is an important inhibitor of the endothelial and lipoprotein lipases and a promising drug target. ANGPTL3 undergoes proprotein convertase processing (RAPR224↓TT) for activation, and the processing site cont
Autor:
Ulla Mandel, Ya-Wen Chen, Tilo Schwientek, Henrik Clausen, Stephen M. Cohen, Katrine T. Schjoldager, Eric P. Bennett
Publikováno v:
Glycoconjugate Journal. 27:435-444
The Drosophila l(2)35Aa gene encodes a UDP-N-acetylgalactosamine: Polypeptide N-acetylgalactosaminyltransferase, essential for embryogenesis and development (J. Biol. Chem. 277, 22623-22638; J. Biol. Chem. 277, 22616-22). l(2)35Aa, also known as pgan
Autor:
Anthony P. Corfield, Stefan Müller, Udo Roth, Katja Engelmann, Stephan Baldus, Tilo Schwientek, Julia Hommer, Franz-Georg Hanisch, Christos Paraskeva, Hanieh Razawi, Georgios Patsos
Publikováno v:
PROTEOMICS. 10:194-202
This is the first differential expression proteomics study on a human syngeneic cellular in vitro progression model of the colorectal adenoma-to-carcinoma sequence, the anchorage-dependent non-tumorigenic adenoma derived cell line AA/C1 and the deriv
Publikováno v:
PROTEOMICS. 7:3264-3277
Identification of mucin-type O-glycosylated proteins with known functions in model organisms like Drosophila could provide keys to elucidate functions of the O-glycan moiety and proteomic analyses of O-glycoproteins in higher eukaryotes remain a chal
Autor:
Ros Graham, Anne Louise Sørensen, Joy Burchell, Mads Agervig Tarp, Kavitha Ramachandran, Joyce Taylor-Papadimitriou, Henrik Clausen, Michael A. Hollingsworth, Vasanthi Sankaranarayanan, Tilo Schwientek, Celso A. Reis, Ulla Mandel
Publikováno v:
Glycobiology. 16:96-107
The MUC1 mucin represents a prime target antigen for cancer immunotherapy because it is abundantly expressed and aberrantly glycosylated in carcinomas. Attempts to generate strong humoral immunity to MUC1 by immunization with peptides have generally
Autor:
Steven B. Levery, Matthew D. Fuller, Henrik Clausen, Hans H. Wandall, Johannes W. Pedersen, Tilo Schwientek
Publikováno v:
Glycobiology. 15:1286-1301
The major neutral glycosphingolipids (GSLs) of High Five insect cells have been extracted, purified, and characterized. It was anticipated that GSLs from High Five cells would follow the arthro-series pathway, known to be expressed by both insects an
Autor:
Joy Burchell, Joyce Taylor-Papadimitriou, Inka Brockhausen, Stephen Gschmeissner, Henrik Clausen, Caroline A. Whitehouse, Martin Dalziel, Tilo Schwientek, Ian McFarlane
Publikováno v:
Journal of Biological Chemistry. 276:11007-11015
In breast cancer, the O-glycans added to the MUC1 mucin are core 1- rather than core 2-based. We have analyzed whether competition by the glycosyltransferase, ST3Gal-I, which transfers sialic acid to galactose in the core 1 substrate, is key to this
Publikováno v:
Journal of the Chemical Society, Perkin Transactions 1. :880-885
The Tn (GalNAcα-Ser/Thr), T [Galβ(1→3)GalNAcα-Ser/Thr], sialyl-Tn [Neu5Acα(2→6)GalNAcα-Ser/Thr] and 2,3-sialyl-T [Neu5Acα(2→3)Galβ(1→3)GalNAcα-Ser/Thr] antigens are examples of tumor-associated carbohydrate antigens expressed by epith