Zobrazeno 1 - 10
of 65
pro vyhledávání: '"Tilmann Ott"'
Autor:
Heinrich Repke, Monika Boomgaarden, Reinhard Sohr, Rainer Harhammer, Ute Schäfer, Tilmann Ott, Peter Henklein
Publikováno v:
Journal of Neurochemistry. 62:1426-1431
The structural requirements for the selective binding of cholecystokinin-8 (CCK-8)-related peptides to peripheral (CCKA) receptors are not sufficiently understood. In this study, the interaction of a series of newly shortened analogues of CCK-8 with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1292273647f70833b7a4f8ad72f418c
https://doi.org/10.1046/j.1471-4159.1994.62041426.x
https://doi.org/10.1046/j.1471-4159.1994.62041426.x
Publikováno v:
British Journal of Pharmacology. 130:1571-1574
The ATP-sensitive K(+) (K(ATP)) channel is a complex of a pore-forming inwardly rectifying K(+) channel (Kir6.2) and a sulphonylurea receptor (SUR). The aim of the present study was to gain further insight into the mechanism of block of K(ATP) channe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0683186d526256e6c106b36ff622fbbf
https://doi.org/10.1038/sj.bjp.0703483
https://doi.org/10.1038/sj.bjp.0703483
Publikováno v:
Bundesgesundheitsblatt - Gesundheitsforschung - Gesundheitsschutz. 42:631-638
Die fur die Repolarisation erforderliche Zeit der Ventrikel kann als QT-Intervall im EKG gemessen werden. Dieses Intervall wird vor allem durch Aktivierung des delayed rectifier K+-Stroms (IK) bestimmt, der aus einer schnellen (IKr) und einer langsam
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c4ef6f2480b3849cef7f2e947ac5dd3e
https://doi.org/10.1007/s001030050175
https://doi.org/10.1007/s001030050175
Publikováno v:
European Journal of Medicinal Chemistry. 27:955-959
The synthesis of a series of cholecystokinin analogues derived from the well-known antagonist Ge 410 (Suc-Tyr(SO3)-Met-Gly-Trp-Met-Asp-β-phenethylamide) is reported. Replacements of l -Trp by d -Trp, Asp by Glu and Met by Nle were carried out and th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::da13c4c0fa15325c0bb62d3af0f1b341
https://doi.org/10.1016/0223-5234(92)90028-y
https://doi.org/10.1016/0223-5234(92)90028-y
Publikováno v:
Pharmacology Biochemistry and Behavior. 38:321-325
The open-field test was used to study the involvement of dopaminergic and serotonergic mechanisms in the effects of 2-bromolisuride on locomotor activity in the rat. 2-Bromolisuride produced a dose-dependent inhibition of spontaneous locomotor activi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b8c31512ee25376d9e33372531f1560
https://doi.org/10.1016/0091-3057(91)90285-a
https://doi.org/10.1016/0091-3057(91)90285-a
Publikováno v:
European Journal of Pharmacology. 180:187-190
The effects of tifluadom, a benzodiazepine-κ-opioid-receptor agonist, on cholecystokinin-octapeptide (CCK-8)-induced antinociception were investigated in the mouse writhing test. When given alone, tifluadom produced pronounced, dose-dependent analge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8748b3a6b9e623b3b4a344b469ad612a
https://doi.org/10.1016/0014-2999(90)90609-a
https://doi.org/10.1016/0014-2999(90)90609-a
Autor:
Olavi Pelkonen, Franz Oesch, Diether Neubert, Rob Kroes, Lewis B. Holmes, Sir Colin Berry, Rolf Schulte-Hermann, Erminio Giavini, Heinz Nau, Frank M. Sullivan, Gerald N. Wogan, Tilmann Ott, Elisabeth Robert-Gnansia, Andrew Czeizel, Nigel A. Brown
Publikováno v:
Regulatory toxicology and pharmacology : RTP. 44(3 Suppl 1)
CONCLUSION REGARDING CLASSIFICATION OF GLUFOSINATE-AMMONIUM: Science Partners' Evaluation Group (Evaluation Group) has conducted an independent analysis of the herbicide glufosinate-ammonium (GA) relative to its potential to cause reproductive toxici
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9796c98b7d8c66b7f2417cdf81b6b70
https://pubmed.ncbi.nlm.nih.gov/16510221
https://pubmed.ncbi.nlm.nih.gov/16510221
Publikováno v:
Life sciences. 66(17)
The class Ia antiarrhythmic agent disopyramide blocks native ATP-sensitive K+ (K(ATP)) channels at micromolar concentrations. The K(ATP) channel is a complex of a pore-forming inwardly rectifying K+ channel (Kir6.2) and a sulfonylurea receptor (SUR).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::026fed9da63be476c7be95f182ec5534
https://pubmed.ncbi.nlm.nih.gov/11261596
https://pubmed.ncbi.nlm.nih.gov/11261596
Publikováno v:
NeuroReport. 3:697-699
We have investigated the effect of cholecystokinin-octapeptide (CCK-8) on [Ca2+]i and protein kinase C (PKC) activity in Jurkat T-cells. CCK-8 produced a transient [Ca2+]i increase in the presence of extracellular Ca2+. While CCKB receptor antagonist
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a741b697afc2e66f442eac1c5386b3dc
https://doi.org/10.1097/00001756-199208000-00011
https://doi.org/10.1097/00001756-199208000-00011
Autor:
Tilmann Ott, Michael Gräfe, Berthold Henning, Eckart Fleck, Stephan Kühne, Bernd J. Zünkler, Alfred G. Hildebrandt
Publikováno v:
Pharmacologytoxicology. 85(1)
Vasoactive agonists like adenosine-5'-triphosphate (ATP) increase intracellular Ca 2+ ([Ca 2+ ] i ) in vascular endothelial cells with an initial peak due to inositol 1,4,5-triphosphate-mediated Ca 2 release from intracellular stores followed by a su
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1f23bd3644a83243e77ccbec7c7315f
https://pubmed.ncbi.nlm.nih.gov/10426157
https://pubmed.ncbi.nlm.nih.gov/10426157